Role of AMPA and NMDA receptors on vasopressin and oxytocin secretion induced by hypertonic extracellular volume expansion

2018 ◽  
Vol 30 (8) ◽  
pp. e12633 ◽  
Author(s):  
Tatiane Vilhena-Franco ◽  
Evandro Valentim-Lima ◽  
Luís C. Reis ◽  
Lucila L. K. Elias ◽  
Jose Antunes-Rodrigues ◽  
...  
Keyword(s):  
Nmda Receptors ◽  
Volume Expansion ◽  
Extracellular Volume ◽  
Ampa And Nmda Receptors ◽  
Extracellular Volume Expansion

Role of Oxytocin in the Natriuresis of Extracellular Volume Expansion

1969 ◽  
Vol 130 (4) ◽  
pp. 1276-1279 ◽  
Author(s):  
S. G. Massry ◽  
H. Vorherr ◽  
C. R. Kleeman
Keyword(s):  
Volume Expansion ◽  
Extracellular Volume ◽  
Extracellular Volume Expansion

Role of the locus coeruleus on blood pressure response and atrial natriuretic peptide secretion following extracellular volume expansion

1999 ◽  
Vol 50 (3) ◽  
pp. 173-177 ◽  
Author(s):  
Janete A Anselmo-Franci ◽  
Maria José A Rocha ◽  
Vera Lúcia Peres-Polon ◽  
Eliane Resende Moreira ◽  
José Antunes-Rodrigues ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Atrial Natriuretic Peptide ◽  
Locus Coeruleus ◽  
Natriuretic Peptide ◽  
Volume Expansion ◽  
Blood Pressure Response ◽  
Extracellular Volume ◽  
Extracellular Volume Expansion ◽  
Peptide Secretion

Role of Cyclic AMP in the Natriuresis of Extracellular Fluid Volume Expansion in the Dog

1977 ◽  
Vol 53 (6) ◽  
pp. 563-571
Author(s):  
R. M. Friedler ◽  
C. Descoeudres ◽  
K. Kurokawa ◽  
W.-J. Kreusser ◽  
S. G. Massry
Keyword(s):  
Body Weight ◽  
Cyclic Amp ◽  
Renal Vein ◽  
Volume Expansion ◽  
Renal Plasma Flow ◽  
Extracellular Volume ◽  
Extracellular Fluid ◽  
Net Production ◽  
Extracellular Volume Expansion

1. The effect of extracellular volume expansion (ECVE) on renal production of cyclic AMP was evaluated in 19 thyroparathyroidectomized dogs. ECVE was produced by the infusion of Ringer bicarbonate solution at a rate of 2 ml min−1 kg−1 body weight; cyclic AMP was measured in plasma obtained from the aorta and renal vein and in the urine. 2. During the natriuresis of ECVE urinary excretion of cyclic AMP, the clearance of cyclic AMP, net nephrogenous cyclic AMP added both to urine and to the renal vein and hence total nephrogenous cyclic AMP increased significantly. 3. This rise in net production of cyclic AMP and a significant natriuresis by the kidney persisted for 60–90 min after discontinuation of active ECVE and return of renal plasma flow to normal. 4. The results support the notion that an increase in the production of cyclic AMP by the kidney may play a role in the natriuresis of ECVE.

Kinin and tubuloglomerular feedback in normal and hydronephrotic rats

1991 ◽  
Vol 260 (6) ◽  
pp. F868-F873 ◽  
Author(s):  
P. Morsing ◽  
A. E. Persson
Keyword(s):  
Volume Expansion ◽  
Turning Point ◽  
Extracellular Volume ◽  
Tubuloglomerular Feedback ◽  
Glomerular Function ◽  
Flow Pressure ◽  
Extracellular Volume Expansion ◽  
And Control ◽  
Stop Flow

The role of bradykinin in resetting the tubuloglomerular feedback (TGF) mechanism was studied with the stop-flow technique in control and hydronephrotic Inactin-anesthetized rats. Glomerular function was assessed by measuring stop-flow pressure (Psf); the maximal decrease in stop-flow pressure (delta Psf) with increased loop of Henle perfusion and the perfusion that elicited half-maximal delta Psf, the turning point (TP), were determined. Bradykinin infusion resulted in resetting of TGF in both control and hydronephrotic rats but in different directions. A decreased sensitivity was found in control rats (TP increased from 18.6 to 26.4 and 16.8 to 22.1 nl/min on systemic and intratubular administration, respectively). In hydronephrotic rats the sensitivity of TGF increased. TP decreased from 19.9 to 15.2 nl/min with bradykinin administered systemically and from 18.4 to 15.0 nl/min on intratubular administration. These results show that exogenous kinin administration mimics the effects of extracellular volume expansion on TGF resetting and demonstrate a difference in resetting in hydronephrotic and control kidneys.

Vascular and renal effects of dopamine during extracellular volume expansion: Role of nitric oxide pathway

Life Sciences ◽  
2006 ◽  
Vol 78 (14) ◽  
pp. 1543-1549 ◽  
Author(s):  
María A. Costa ◽  
Rosana Elesgaray ◽  
Analía Loria ◽  
Ana María Balaszczuk ◽  
Cristina Arranz
Keyword(s):  
Nitric Oxide ◽  
Volume Expansion ◽  
Extracellular Volume ◽  
Renal Effects ◽  
Extracellular Volume Expansion ◽  
Nitric Oxide Pathway

Role of prostaglandins on the renal effects of angiotensin and interstitial pressure during volume expansion

1993 ◽  
Vol 265 (6) ◽  
pp. R1469-R1474 ◽  
Author(s):  
J. M. Pinilla ◽  
A. Alberola ◽  
J. D. Gonzalez ◽  
T. Quesada ◽  
F. J. Salazar
Keyword(s):  
Volume Expansion ◽  
Left Kidney ◽  
Extracellular Volume ◽  
Isotonic Saline ◽  
Sodium Reabsorption ◽  
Ang Ii ◽  
Synthesis Inhibitor ◽  
Extracellular Volume Expansion ◽  
The Right

This study was undertaken to determine, in anesthetized dogs, the role of renal prostaglandins (PG) in mediating the natriuretic response to increased renal interstitial hydrostatic pressure (RIHP) during extracellular volume expansion (ECVE) with isotonic saline. It was also determined if the intrarenal angiotensin II (ANG II) effects during ECVE are potentiated by the inhibition of PG synthesis. ECVE induced similar elevations of RIHP, natriuresis, and fractional lithium excretion in dogs treated (n = 7) and not treated with a PG synthesis inhibitor (n = 5). In other experimental groups, the effects of the intrarenal maintenance of ANG II levels (n = 6) by infusing captopril and ANG II into the right renal artery were compared with those induced by the simultaneous infusion of captopril, ANG II, and a PG synthesis inhibitor (n = 6). In response to ECVE, renal blood flow and glomerular filtration rate were similar in both kidneys when ANG II levels were maintained constant and were significantly higher in the left kidney when ANG II levels were maintained constant and PG synthesis was inhibited in the right kidney. However, when compared with the left kidney, the ECVE-induced increments of natriuresis and RIHP in the right kidney were reduced by the same magnitude when intrarenal ANG II was maintained constant with (36 and 53%, respectively) and without (40 and 54%, respectively) the simultaneous PG synthesis inhibition. Our results indicate that during ECVE, renal PGs do not play an important role in mediating the RIHP-induced increments in natriuresis and decrements in proximal sodium reabsorption. (ABSTRACT TRUNCATED AT 250 WORDS)

scholarly journals Role of extracellular volume expansion in the development of DOC-salt hypertension in the rat.

Hypertension ◽  
1982 ◽  
Vol 4 (5) ◽  
pp. 620-624 ◽  
Author(s):  
M F Villamil ◽  
C Amorena ◽  
J Ponce-Hornos ◽  
A Müller ◽  
A C Taquini
Keyword(s):  
Volume Expansion ◽  
Extracellular Volume ◽  
Salt Hypertension ◽  
Extracellular Volume Expansion

Role of nitric oxide pathway in hypotensive and renal effects of furosemide during extracellular volume expansion

2004 ◽  
Vol 22 (8) ◽  
pp. 1561-1569 ◽  
Author(s):  
Mar??a A Costa ◽  
Anal??a Loria ◽  
Rosana Elesgaray ◽  
Ana Mar??a Balaszczuk ◽  
Cristina Arranz
Keyword(s):  
Nitric Oxide ◽  
Volume Expansion ◽  
Extracellular Volume ◽  
Renal Effects ◽  
Extracellular Volume Expansion ◽  
Nitric Oxide Pathway
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