scholarly journals Dehydroepiandrosterone Heightens Aggression and Increases Androgen Receptor and Aromatase mRNA Expression in the Brain of a Male Songbird

2016 ◽  
Vol 28 (12) ◽  
Author(s):  
D. W. Wacker ◽  
S. Khalaj ◽  
L. J. Jones ◽  
T. L. Champion ◽  
J. E. Davis ◽  
...  
Keyword(s):  
Androgen Receptor ◽  
Mrna Expression ◽  
Aromatase Mrna ◽  
The Brain

Distribution of aromatase mRNA and protein in the brain and pituitary of female rainbow trout: Comparison with estrogen receptor ?

2003 ◽  
Vol 462 (2) ◽  
pp. 180-193 ◽  
Author(s):  
Arnaud Menuet ◽  
Isabelle Anglade ◽  
Remy Le Guevel ◽  
Elisabeth Pellegrini ◽  
Farzad Pakdel ◽  
...  
Keyword(s):  
Estrogen Receptor ◽  
Rainbow Trout ◽  
Aromatase Mrna ◽  
The Brain

Abstract 814: Atorvastatin Attenuates Oxidative Stress And Improves Neuronal Nitric Oxide Synthase In The Brain Stem Of Heart Failure Mice

Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Joseph Francis ◽  
Li Yu ◽  
Anuradha Guggilam ◽  
Srinivas Sriramula ◽  
Irving H Zucker
Keyword(s):  
Oxidative Stress ◽  
Nitric Oxide ◽  
Myocardial Infarction ◽  
Heart Failure ◽  
Brain Stem ◽  
Mrna Expression ◽  
Natriuretic Peptide ◽  
Left Ventricular ◽  
Neuronal Nos ◽  
The Brain

3-Hydroxyl-3-methylglutaryl coenzyme A reductase inhibitors (statins) have been shown to reduce the incidence of myocardial infarction independent of their lipid-lowering effects. Nitric oxide (NO) in the central nervous system contributes to cardiovascular regulatory mechanisms. Imbalance between nitric oxide (NO) and superoxide anion (O 2 . − ) in the brain may contribute to enhanced sympathetic drive in heart failure (HF). This study was done to determine whether treatment with atorvastatin (ATS) ameliorates the imbalance between NO and O 2 . − production in the brain stem and contributes to improvement of left ventricular (LV) function. Methods and Results: Myocardial infarction (MI) was induced by ligation of the left coronary artery or sham surgery. Subsequently, mice were treated with ATS (10 μg/kg) (MI + ATS), or vehicle (MI + V). After 5 weeks, echocardiography revealed left ventricular dilatation in MI mice. Realtime RT-PCR indicated an increase in the mRNA expression of the LV hypertrophy markers, atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP). Neuronal NOS (nNOS) and endothelial NOS (eNOS) mRNA expression were significantly reduced, while that of NAD(P)H oxidase subunit (gp91phox) expression was elevated in the brain stem of MI mice. Compared with sham-operated mice, ATS-treated mice showed reduced cardiac dilatation, decreased ANP and BNP in the LV. ATS also reduced gp91phox expression and increased nNOS mRNA expression in the brain stem, while no changes in eNOS and iNOS were observed. Conclusion: These findings suggest that ATS reduces oxidative stress and increases neuronal NOS in the brain stem, and improves left ventricular function in heart failure.

Cloning of the rat Gadd45 cDNA and its mRNA expression in the brain

Gene ◽  
1994 ◽  
Vol 151 (1-2) ◽  
pp. 253-255 ◽  
Author(s):  
Toru Yoshida ◽  
Edward L. Schneider ◽  
Nozomu Mori
Keyword(s):  
Mrna Expression ◽  
The Brain

Activation of Androgen Receptor-Associated Protein 70 (ARA70) mRNA Expression in Ovarian Cancer

2001 ◽  
Vol 80 (2) ◽  
pp. 132-138 ◽  
Author(s):  
Patricia A. Shaw ◽  
Paula V.C. Rittenberg ◽  
Theodore J. Brown
Keyword(s):  
Ovarian Cancer ◽  
Androgen Receptor ◽  
Mrna Expression ◽  
Receptor Associated Protein
Sign in / Sign up

Export Citation Format

Share Document