scholarly journals Gonadal Steroids Differentially Modulate the Actions of Orphanin FQ/Nociceptin at A Physiologically Relevant Circuit Controlling Female Sexual Receptivity

2014 ◽  
Vol 26 (5) ◽  
pp. 329-340 ◽  
Author(s):  
A. Borgquist ◽  
V. M. Rivas ◽  
M. Kachani ◽  
K. Sinchak ◽  
E. J. Wagner
Keyword(s):  
Gonadal Steroids ◽  
Sexual Receptivity ◽  
Orphanin Fq ◽  
Female Sexual Receptivity

Sex hormone binding globulin stimulates female sexual receptivity

2000 ◽  
Vol 874 (1) ◽  
pp. 24-29 ◽  
Author(s):  
J.D. Caldwell ◽  
B.D. Moe ◽  
J. Hoang ◽  
T. Nguyen
Keyword(s):  
Sex Hormone ◽  
Sex Hormone Binding Globulin ◽  
Sexual Receptivity ◽  
Hormone Binding ◽  
Female Sexual Receptivity

scholarly journals Drosulfakinin signaling modulates female sexual receptivity in Drosophila

2021 ◽  
Author(s):  
Chuan Zhou ◽  
Tao Wang ◽  
Biyang Jing ◽  
Bowen Deng ◽  
Kai Shi ◽  
...  
Keyword(s):  
Sexual Behavior ◽  
Neuronal Activity ◽  
Input Signal ◽  
Sexual Receptivity ◽  
Innate Behavior ◽  
Female Sexual Behavior ◽  
Downstream Signaling ◽  
Biological Importance ◽  
Survival And Reproduction ◽  
Female Sexual Receptivity

Female sexual behavior as an innate behavior is of prominent biological importance for survival and reproduction. However, molecular and circuit mechanisms underlying female sexual behavior is not well understood. Here, we identify the Cholecystokinin-like peptide Drosulfakinin (DSK) promotes female sexual behavior in Drosophila. Manipulation both Dsk and DSK neuronal activity impact female sexual receptivity. In addition, we reveal that Dsk-expressing neurons receive input signal from R71G01GAL4 neurons to promote female sexual receptivity. Based on intersectional technique, we further found the regulation of female sexual behavior relies mainly on medial DSK neurons rather than lateral DSK neurons, and medial DSK neurons modulate female sexual behavior by acting on its receptor CCKLR-17D3. Thus, we characterized DSK/CCKLR-17D3 as R71G01GAL4 neurons downstream signaling to regulate female sexual behavior.

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