Glycine release from astrocytes via functional reversal of GlyT1

2016 ◽  
Vol 140 (3) ◽  
pp. 395-403 ◽  
Author(s):  
Koji Shibasaki ◽  
Nobutake Hosoi ◽  
Ryosuke Kaneko ◽  
Makoto Tominaga ◽  
Katsuya Yamada
Keyword(s):  
Glycine Release

scholarly journals Glycine Release from Radial Cells Modulates the Spontaneous Activity and Its Propagation during Early Spinal Cord Development

2010 ◽  
Vol 30 (1) ◽  
pp. 390-403 ◽  
Author(s):  
A.-L. Scain ◽  
H. Le Corronc ◽  
A.-E. Allain ◽  
E. Muller ◽  
J.-M. Rigo ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spontaneous Activity ◽  
Spinal Cord Development ◽  
Glycine Release

Voltage dependence of conductance changes evoked by glycine release in the zebrafish brain

1995 ◽  
Vol 73 (6) ◽  
pp. 2404-2412 ◽  
Author(s):  
P. Legendre ◽  
H. Korn
Keyword(s):  
Voltage Dependence ◽  
Reversal Potential ◽  
Voltage Sensitivity ◽  
M Cell ◽  
Open Probability ◽  
Similar Time ◽  
Whole Cell ◽  
Glycine Release ◽  
Cell Recording ◽  
Voltage Dependent

1. The kinetics and mechanisms underlying the voltage dependence of inhibitory postsynaptic currents (IPSCs) recorded in the Mauthner cell (M cell) were investigated in the isolated medulla of 52-h-old zebrafish larvae, with the use of whole cell and outside-out patch-clamp recordings. 2. Spontaneous miniature IPSCs (mIPSCs) were recorded in the presence of 10(-6) M tetrodotoxin (TTX), 10 mM MgCl2, and 0.1 mM [CaCl2]o. Depolarizing the cell from -50 to +50 mV did not evoke any significant change in the distribution of mIPSC amplitudes, whereas synaptic currents were prolonged at positive voltages. The average decay time constant was increased twofold at +50 mV. 3. The voltage dependence of the kinetics of glycine-activated channels was first investigated during whole cell recording experiments. Currents evoked by voltage steps in the presence of glycine (50 microM) were compared with those obtained without glycine. The increase in chloride conductance (gCl-) evoked by glycine was time and voltage dependent. Inactivation and reactivation of the chloride current were observed during voltage pulses from 0 to -50 mV and from -50 to 0 mV, respectively, and they occurred with similar time constants (2-3 s). During glycine application, voltage-ramp analysis revealed a shift in the reversal potential (ECl-) occurring at all [Cl-]i tested. 4. The basis of the voltage sensitivity of glycine-evoked gCl- was first analyzed by measuring the relative changes in the total open probability (NPo) of glycine-activated channels with voltage.(ABSTRACT TRUNCATED AT 250 WORDS)

scholarly journals Substance P Abolishes the Facilitatory Effect of ATP on Spontaneous Glycine Release in Neurons of the Trigeminal Nucleus Pars Caudalis

2001 ◽  
Vol 21 (9) ◽  
pp. 2983-2991 ◽  
Author(s):  
Zhi-Ming Wang ◽  
Shutaro Katsurabayashi ◽  
Jeong-Seop Rhee ◽  
Malcolm Brodwick ◽  
Norio Akaike
Keyword(s):  
Substance P ◽  
Facilitatory Effect ◽  
Trigeminal Nucleus ◽  
Glycine Release

Characterization of glycine release mediated by glycine transporter 1 stably expressed in HEK-293 cells

1997 ◽  
Vol 49 (1-2) ◽  
pp. 89-94 ◽  
Author(s):  
Kazuko Sakata ◽  
Kohji Sato ◽  
Patrick Schloss ◽  
Heinrich Betz ◽  
Shoichi Shimada ◽  
...  
Keyword(s):  
Hek 293 ◽  
Hek 293 Cells ◽  
Glycine Release ◽  
Glycine Transporter 1 ◽  
Glycine Transporter ◽  
293 Cells

Effects of persistent nociception on periaqueductal gray glycine release

Neuroscience ◽  
2000 ◽  
Vol 97 (2) ◽  
pp. 311-316 ◽  
Author(s):  
S Maione ◽  
I Marabese ◽  
F.sca Rossi ◽  
L Berrino ◽  
E Palazzo ◽  
...  
Keyword(s):  
Periaqueductal Gray ◽  
Glycine Release
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