scholarly journals Evaluation of the guaiac fecal occult blood test for detection of gastrointestinal bleeding in the rhesus macaque ( Macaca mulatta )

2019 ◽  
Vol 49 (1) ◽  
pp. 16-25
Author(s):  
Rachel Elizabeth Cooper ◽  
Eric Kenneth Hutchinson ◽  
Jessica Marie Izzi
Keyword(s):  
Gastrointestinal Bleeding ◽  
Rhesus Macaque ◽  
Macaca Mulatta ◽  
Blood Test ◽  
Fecal Occult Blood Test ◽  
Occult Blood ◽  
Fecal Occult Blood ◽  
Occult Blood Test ◽  
Fecal Occult

scholarly journals A comparative study of chemical and immunological method of fecal occult blood test in the diagnosis of occult lower gastrointestinal bleeding

2014 ◽  
Vol 39 (2) ◽  
pp. 52-56 ◽  
Author(s):  
F Yeasmin ◽  
MA Ali ◽  
MA Rahman ◽  
T Sultana ◽  
MQ Rahman ◽  
...  
Keyword(s):  
Gastrointestinal Bleeding ◽  
Blood Test ◽  
Chemical Method ◽  
Fecal Occult Blood Test ◽  
False Positive Rate ◽  
Occult Blood ◽  
Fecal Occult Blood ◽  
Occult Blood Test ◽  
Immunological Method ◽  
Fecal Occult

Fecal occult blood test is the most widely used screening test for diagnosis of gastrointestinal bleeding disorders specially colorectal carcinoma. Among the various methods of fecal occult blood tests, chemical method is being used commonly, but the method has some drawbacks like low participation rate, high false positive rate, low sensitivity etc. To overcome these short comings, newer immunological method was introduced. This study evaluated the role of immunological method of fecal blood test in the diagnosis of occult lower GIT bleeding. Stool samples from two hundred patients were examined by both chemical and immunological method. The patients who were positive by any or both methods of occult blood test, were advised for colonoscopy. During colonoscopy tissues were taken for histopathology which was the gold standard of this study. Among 110 OBT positive patients pathological lesions were detected in 65 patients by colonoscopy and histopathology. The diseases detected by colonoscopy and histopathology 18 colorectal polyp, 8 colorectal cancer, 24 ulcerative lesions and 5 inflammatory bowel disease etc. Regarding comparative analysis of chemical and immunological method, the higher sensitivity (95.4% vs. 49.2%), specificity (44.4% vs. 37.8%), accuracy (74.5% vs. 44.5%), PPV (71.3% vs. 53.3%) and NPV (87% vs. 34%) of immunological method than chemical method was observed. Thus immunological method of fecal occult blood test was appeared to be a better alternative to conventional chemical method of fecal occult blood test in the diagnosis of occult lower GIT bleeding. DOI: http://dx.doi.org/10.3329/bmrcb.v39i2.19641 Bangladesh Med Res Counc Bull 2013; 39: 52-56

scholarly journals Clinical analysis of gastrointestinal bleeding in patients with severe coronavirus disease (COVID-19): A retrospective observational study

2020 ◽  
Author(s):  
Jinfen Dai ◽  
Song Hu ◽  
Yi Chen ◽  
Pengbo Wu ◽  
Mei Liu
Keyword(s):  
Blood Transfusion ◽  
Gastrointestinal Bleeding ◽  
Blood Test ◽  
Fecal Occult Blood Test ◽  
Occult Blood ◽  
Antiplatelet Drugs ◽  
Fecal Occult Blood ◽  
Severe Bleeding ◽  
Occult Blood Test ◽  
Fecal Occult

Abstract Background: The epidemic of Novel coronavirus disease 2019(COVID-19) has attracted the great attention of people all over the world. Gastrointestinal bleeding in patients with COVID-19 has been studied rarely. We mean to investigate the clinical characteristics of gastrointestinal bleeding in patients with severe coronavirus disease (COVID-19).Methods: Nineteen severe COVID-19 patients with gastrointestinal bleeding were retrospectively studied. Clinical data, including medical history, symptoms, laboratory characteristics, and treatment, were collected and analyzed. We also compared the characteristics of patients with different degrees of bleeding.Results: Fourteen patients (73.6%) were men. Mean age was 63.8 (±15.6) years. Most patients (89.4%) had no history of gastrointestinal bleeding. The most common presentation of gastrointestinal bleeding was a positive fecal occult blood test (15/19 cases, 78.9%). Fifteen patients (78.9%) did not require blood transfusion. Five of 15 patients (33%) received anticoagulants and antiplatelet drugs before gastrointestinal bleeding in the mild bleeding group, and 2/4 (50%) in the severe bleeding group. Four of 15 patients (27%) died in the mild bleeding group and no patients died in the severe bleeding group.Conclusions: The presentations of gastrointestinal bleeding in severe COVID-19 patients are not obvious, and frequent fecal occult blood test is needed to detect gastrointestinal bleeding early. Patients receiving anticoagulants and antiplatelet drugs need a close observation for gastrointestinal bleeding. Gastrointestinal bleeding may not increase the mortality, after giving blood transfusion support therapy.

Sa107 THE ROLE OF FECAL OCCULT BLOOD TEST IN THE EVALUATION OF ANEMIA IN THE INTENSIVE-CARE UNIT: A RETROSPECTIVE STUDY ASSESSING THE CLINICAL UTILITY OF THE TEST

2021 ◽  
Vol 160 (6) ◽  
pp. S-423-S-424
Author(s):  
Thanita Thongtan ◽  
Anasua Deb ◽  
Ashley Maveddat ◽  
Paibul Suriyawongpaisal ◽  
Passisd Laoveeravat ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Blood Test ◽  
Clinical Utility ◽  
Fecal Occult Blood Test ◽  
Occult Blood ◽  
Fecal Occult Blood ◽  
Occult Blood Test ◽  
Fecal Occult
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