scholarly journals SNP-based genetic characterization of the Tulane National Primate Research Center's conventional and specific pathogen-free rhesus macaque (Macaca mulatta ) populations

2017 ◽  
Vol 47 (1) ◽  
pp. 29-34
Author(s):  
Sree Kanthaswamy ◽  
Jillian Ng ◽  
Robert F. Oldt ◽  
Kathrine Phillippi-Falkenstein ◽  
H. Michael Kubisch
Keyword(s):  
Rhesus Macaque ◽  
Macaca Mulatta ◽  
Genetic Characterization ◽  
Primate Research ◽  
Specific Pathogen Free ◽  
Specific Pathogen ◽  
National Primate Research

scholarly journals Trauma rates and patterns in specific pathogen free (SPF) rhesus macaque (Macaca mulatta ) groups

2018 ◽  
Vol 80 (3) ◽  
pp. e22742 ◽  
Author(s):  
Ronda C. Stavisky ◽  
Jacklyn K. Ramsey ◽  
Tracy Meeker ◽  
Melissa Stovall ◽  
Maria M. Crane
Keyword(s):  
Rhesus Macaque ◽  
Macaca Mulatta ◽  
Specific Pathogen Free ◽  
Specific Pathogen

scholarly journals Mitigating Chinese-Indian rhesus macaque (Macaca mulatta) hybridity at the California National Primate Research Center (CNPRC)

2016 ◽  
Vol 45 (6) ◽  
pp. 333-335 ◽  
Author(s):  
Sree Kanthaswamy ◽  
Jillian Ng ◽  
Jennifer Broatch ◽  
Jennifer Short ◽  
Jeffrey Roberts
Keyword(s):  
Rhesus Macaque ◽  
Macaca Mulatta ◽  
Research Center ◽  
Primate Research ◽  
Indian Rhesus Macaque ◽  
National Primate Research

scholarly journals Interpretation of serological test results for Simian herpes B virus

2001 ◽  
Vol 35 (4) ◽  
pp. 315-320 ◽  
Author(s):  
S. E. Wolfensohn ◽  
R. Gopal
Keyword(s):  
Macaca Mulatta ◽  
Macaca Fascicularis ◽  
Screening Programme ◽  
Serological Test ◽  
Test Results ◽  
Specific Pathogen Free ◽  
B Virus ◽  
Specific Pathogen ◽  
Herpes B Virus ◽  
Experimental Group

In 1992 an annual Simian herpes B virus (BV) screening programme for an experimental group of macaque monkeys ( Macaca mulatta and Macaca fascicularis) was initiated with the aim of establishing a specific pathogen free (SPF) colony. In June 1999 one animal was found to be unexpectedly BV positive (non-negative). The investigation of this result highlights some of the issues and difficulties that may be encountered in such a programme.

scholarly journals Molecular Characterization and Pathogenicity of Chicken Parvovirus (ChPV) in Specific Pathogen-Free Chicks Infected Experimentally

Pathogens ◽  
2020 ◽  
Vol 9 (8) ◽  
pp. 606
Author(s):  
Luis Fabian N. Nuñez ◽  
Silvana H. Santander-Parra ◽  
David I. De la Torre ◽  
Lilian R. M. de Sá ◽  
Marcos R. Buim ◽  
...  
Keyword(s):  
Plasma Cells ◽  
Genetic Characterization ◽  
Molecular Level ◽  
Molecular Characteristics ◽  
Intestinal Segments ◽  
Specific Pathogen ◽  
Infiltrating Lymphocytes ◽  
Experimental Group ◽  
Experimental Challenge

Chicken parvovirus (ChPV) is an agent frequently associated with runting stunting syndrome (RSS). This syndrome has been reported in association with ChPV in many countries, including Brazil; however, studies characterizing the virus on a molecular level are scarce, and ChPV pathogenicity in day-old chicks remains unclear. The aim of the present work was to establish the molecular characteristics of ChPV, determine the pathogenicity of ChPV in SPF chicks and detect and quantify ChPV by qPCR in several tissues and chicks of different ages. The experimental challenge was performed at one day of age, and daily and weekly observations were performed and five birds from each experimental group (mock and infected birds) were euthanized to perform the different analysis. ChPV genome copies were detected and quantified by qPCR in gut, spleen, thymus, kidney, pancreas, proventriculus and bursa. Clinically, the infected group presented with diarrhea 24 h post-infection, which persisted until 42 days of age. The small intestine was distended, and its contents were aqueous and foamy. Enteritis and dilated crypts with cyst shapes were observed in intestinal segments. Acute pancreatitis associated with lymphocytic nodules, infiltrating lymphocytes and plasma cells between the pancreatic acinus was observed. Koch’s postulate was demonstrated and the genetic characterization of the VP1 gene showed that the Brazilian ChPV isolate belongs to the ChPV II group.

scholarly journals Pathogenicity of Mycoplasma synoviae in Broiler Chickens

1998 ◽  
Vol 35 (3) ◽  
pp. 178-190 ◽  
Author(s):  
S. B. Lockaby ◽  
F. J. Hoerr ◽  
L. H. Lauerman ◽  
S. H. Kleven
Keyword(s):  
Broiler Chickens ◽  
Specific Pathogen Free ◽  
Skeletal System ◽  
Chain Reaction ◽  
Lesion Development ◽  
Mycoplasma Synoviae ◽  
Specific Pathogen ◽  
Upper Respiratory ◽  
Polymerase Chain

Six isolates of Mycoplasma synoviae, identified as WVU 1853, K1968, K1858, 92D8034, F10–2AS, and FMT, were compared for pathogenicity in broiler chickens. Specific-pathogen-free chickens were inoculated, in two groups of 20, with each isolate by footpad or eyedrop inoculation at 1 day of age and were examined at necropsy 7, 14, 28, and 42 days postinoculation. Specimens were taken for histopathology, culture, polymerase chain reaction assay, and hemagglutination-inhibition serology. Isolates were grouped according to pathogenicity on the basis of differences in lesion development and tissue distribution in the respiratory system, other viscera, and the skeletal system. K1968 (pathogenic) induced lesions in all sites examined in both the footpad and eyedrop inoculation groups. It was detected in all sites following footpad inoculation and in all sites except viscera following eyedrop inoculation. WVU 1853, K1858, and 92D8034 (moderately pathogenic) induced lesions and were detected in all sites following footpad inoculation. With eyedrop inoculation, lesions were identified only in upper and lower respiratory sites, and organisms were detected only in upper respiratory sites. F10–2AS (moderately pathogenic) was similar; however, footpad inoculation failed to induce visceral lesions or permit organism detection in any site. F10–2AS was detected in upper and lower respiratory tissues following eyedrop inoculation. FMT (mildly pathogenic) induced only upper respiratory lesions when either footpad or eyedrop inoculation was used, and detection was restricted to upper respiratory sites following eyedrop inoculation. These results are useful in comparative evaluations of the virulence of other M. synoviae isolates and form a basis for characterization of virulence factors of M. synoviae.

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