Comparison of indirect and direct blood pressure measurements in baboons during ketamine anaesthesia

2014 ◽  
Vol 43 (4) ◽  
pp. 217-224 ◽  
Author(s):  
Kristen R. Yeung ◽  
Joanne M. Lind ◽  
Scott J. Heffernan ◽  
Neroli Sunderland ◽  
Annemarie Hennessy ◽  
...  
Author(s):  
Christopher K. Smith ◽  
Anthony L. Ashley ◽  
Xiaojuan Zhu ◽  
Andrew C. Cushing

Abstract OBJECTIVE To evaluate the level of agreement (LOA) between direct and oscillometric blood pressure (BP) measurements and the ability of oscillometric measurements to accurately detect hypotension in anesthetized chimpanzees (Pan troglodytes). ANIMALS 8 captive, adult chimpanzees. PROCEDURES During prescheduled annual examinations, each chimpanzee underwent general anesthesia and patient monitoring for their examination, echocardiography for a concurrent study, and measurement of direct BP with the use of tibial artery catheterization and oscillometry with the use of a cuff placed around a brachium and a cuff placed around the second digit of the contralateral forelimb for the present study. Bland-Altman plots were generated to compare results for direct and oscillometric BP measurements. Mean bias and 95% LOAs were calculated for oscillometric measurements of systolic arterial pressure (SAP), diastolic arterial pressure (DAP), and mean arterial pressure (MAP) for each cuff site. Sensitivity and specificity in detecting hypotension were also determined for each cuff site. RESULTS There were 74 paired direct and brachial oscillometric measurements of each, SAP, MAP, and DAP and 66 paired direct and digit oscillometric measurements of each, SAP, MAP, and DAP. Only brachial oscillometric measurements of MAP had adequate sensitivity (78%) and specificity (95%) to accurately detect hypotension, and this technique also had the least mean bias (0.8 mm Hg; 95% LOA, –29 to 31 mm Hg). CONCLUSIONS AND CLINICAL RELEVANCE Results indicated that brachial oscillometric measurement of MAP provided reasonable agreement with tibial arterial direct MAP measurement and performed well in diagnosing hypotension in anesthetized chimpanzees.


1981 ◽  
Vol 15 (1) ◽  
pp. 37-40 ◽  
Author(s):  
Wayne T. Corbett ◽  
Harry M. Schey ◽  
Noel D. M. Lehner ◽  
A. Wayne Greene

Blood pressures obtained from anaesthetized non-human primates by this indirect, noninvasive method correlate well with direct blood pressure measurements on anaesthetized animals (systolic R = 0·959, diastolic R = 0·946) and on conscious subjects (R = 0·84). Between- and within-animal variances of indirectly-obtained blood pressure recordings in anaesthetized animals were relatively small. The systolic blood pressure standard deviation was 11·566 among animals and 2·233 within animals, diastolic 7·618 and 0·475 respectively.


1976 ◽  
Vol 41 (5) ◽  
pp. 806-809 ◽  
Author(s):  
C. A. McMahan ◽  
H. S. Wigodsky ◽  
G. T. Moore

The accuracy and precision of indirect blood pressure measurements in baboons were studied by comparing the results of indirect measurements with simultaneous direct measurements. The indirect measurements were made by four observers using a Doppler ultrasound instrument. A statistically significant difference between the two methods was found for systolic blood pressure but not for diastolic blood pressure. The indirect systolic averaged 13.8mmHg higher than direct systolic and was found to be more precise than the indirect diastolic. The difference in blood pressure obtained by the two methods varied over animals and observers with an interaction between animalsand observers. The effect of arm was examined by performing direct blood pressure measurements in both arms. No statistically significant arm effect was found.


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