In vitro behavior of poly-lactic-co-glycolic acid microspheres containing minocycline, metronidazole, and ciprofloxacin

2016 ◽  
Vol 8 (2) ◽  
pp. e12201 ◽  
Author(s):  
Maryam Torshabi ◽  
Hanieh Nojehdehian ◽  
Fahimeh S. Tabatabaei
Keyword(s):  
Glycolic Acid

scholarly journals Comparison of the Cerumenolytic Activities of New and Currently Used Agents

2021 ◽  
pp. 014556132098606
Author(s):  
Nguyen Quynh Anh ◽  
Pawin Numthavaj ◽  
Thongchai Bhongmakapat
Keyword(s):  
Salicylic Acid ◽  
Sodium Bicarbonate ◽  
Potassium Hydroxide ◽  
Glycolic Acid ◽  
Statistical Significance ◽  
In Vitro Study ◽  
Distilled Water ◽  
Moderate Amount ◽  
All Solutions

Objectives: This study compared the cerumen dissolution activities of 7.5% sodium bicarbonate, 5% potassium hydroxide, 10% lactic acid, 3% salicylic acid, 10% glycolic acid, and distilled water. Methods: An in vitro study was conducted with 36 cerumen samples. The cerumenolytic activities of the 6 agents were assessed by recording the degree of cerumen disintegration using digital photography at 15 minutes, 30 minutes, 1 hour, 2 hours, and 12 hours. The undissolved cerumen that remained after 12 hours was removed from the solutions and weighed after drying. Results: Potassium hydroxide showed the fastest cerumenolytic activity, dissolving a moderate amount of cerumen at 30 minutes, while glycolic acid and salicylic acid caused no visible changes in the cerumen samples. Samples treated with potassium hydroxide and sodium bicarbonate exhibited higher degrees of disintegration compared to samples treated with distilled water (odds ratio and 95% CI: 273.237 [0.203-367 470.4] and 1.129 [0.002-850.341], respectively). The greatest reduction in cerumen weight was associated with the use of sodium bicarbonate; however, this result did not reach statistical significance. Conclusions: Among the solutions tested, 5% potassium hydroxide showed the fastest dissolution activity, yielding moderate disintegration within only 30 minutes. In terms of residual cerumen weight within 12 hours, all solutions exhibited equivalent effectiveness in the disintegration of cerumen.

Cytotoxicity of different concentrations of glycolic acid and its effects on root dentin microhardness – An in vitro study

2021 ◽  
Author(s):  
Matheus A. Souza ◽  
Karolina F. Bischoff ◽  
Bárbara D. C. Rigo ◽  
Larissa Piuco ◽  
Ana V. L. Didoné ◽  
...  
Keyword(s):  
Glycolic Acid ◽  
In Vitro Study ◽  
Vitro Study ◽  
Root Dentin
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