Lifestyle Risk Factors and Cognitive Outcomes from the Multidomain Dementia Risk Reduction Randomized Controlled Trial, Body Brain Life for Cognitive Decline ( BBL‐CD )

2020 ◽  
Vol 68 (11) ◽  
pp. 2629-2637
Author(s):  
Mitchell McMaster ◽  
Sarang Kim ◽  
Linda Clare ◽  
Susan J. Torres ◽  
Nicolas Cherbuin ◽  
...  
PLoS ONE ◽  
2021 ◽  
Vol 16 (6) ◽  
pp. e0251662
Author(s):  
Mark Kaddumukasa ◽  
Josephine Najjuma ◽  
Scovia Nalugo Mbalinda ◽  
Martin N. Kaddumukasa ◽  
Jane Nakibuuka ◽  
...  

Introduction Stroke burden is rapidly increasing globally. Modifiable risk factors offer an opportunity to intervene, and targeting hypertension is a key actionable target for stroke risk reduction in sub-Saharan Africa. This 3-site planned randomized controlled trial builds on promising preliminary data. Methods A total of 246 Ugandan adults will be recruited randomized to experimental intervention vs. enhanced treatment control. Intervention participants will receive six weekly group-format stroke risk reduction self-management training sessions, and the controls will receive information on cardiovascular risk. The primary study outcome is systolic B.P. measured at baseline, 13-week, 24 weeks (6 months). Secondary outcomes include other biological and behavioral stroke risk factors. Discussion The curriculum-guided self-management TargetEd MAnageMent Intervention (TEAM) program is anticipated to reduce the stroke burden in Uganda. Trial registration ClinicalTrials.gov identifier: NCT04685408, registered on 28 December 2020.


2020 ◽  
Vol 141 ◽  
pp. 106302
Author(s):  
María Barroso ◽  
M. Dolors Zomeño ◽  
Jorge L. Díaz ◽  
Silvia Pérez-Fernández ◽  
Ruth Martí-Lluch ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document