scholarly journals Older Sepsis Survivors Suffer Persistent Disability Burden and Poor Long‐Term Survival

2020 ◽  
Vol 68 (9) ◽  
pp. 1962-1969 ◽  
Author(s):  
Robert T. Mankowski ◽  
Stephen D. Anton ◽  
Gabriela L. Ghita ◽  
Babette Brumback ◽  
Michael C. Cox ◽  
...  
Keyword(s):  
Term Survival ◽  
Long Term Survival ◽  
Sepsis Survivors ◽  
Persistent Disability

Depression and Long-Term Survival Among South Korean Sepsis Survivors

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Tak Kyu Oh ◽  
Hye Youn Park ◽  
In-Ae Song
Keyword(s):  
Term Survival ◽  
Long Term Survival ◽  
South Korean ◽  
Sepsis Survivors

scholarly journals Older Sepsis Survivors Suffer Persistent Disability Burden and Poor Long-Term Survival

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 138-139
Author(s):  
Robert Mankowski ◽  
Stephen Anton ◽  
Gabriela Ghita ◽  
Christiaan Leeuwenburgh ◽  
Lyle Moldawer ◽  
...  
Keyword(s):  
Performance Status ◽  
Middle Aged ◽  
Term Survival ◽  
Prospective Longitudinal Study ◽  
Discharge Disposition ◽  
Sepsis Survivors ◽  
Persistent Disability ◽  
Prospective Longitudinal

Abstract As in-hospital sepsis mortality has decreased, more “sepsis survivors” are progressing into poorly characterized long-term outcomes. The purpose of this study was to describe the current epidemiology of sepsis in older adults compared to middle-aged and young adults. Design: Prospective longitudinal study with patients categorized into young (≤ 45 years), middle-aged (46-64 years) and older (≥ 65 years) patient groups. 328 sepsis patients were characterized by a) baseline demographics and predisposition factors, b) septic event, c) hospital outcomes and discharge disposition, d) 12-month mortality and e) Zubrod Performance status, physical function and cognitive function at three, six and 12-month follow-up. Follow-up visits were not completed due to death (in 68) and withdrawal of consent (in 32). Compared to young and middle-aged patients, older patients had: 1) significantly more comorbidities at presentation (example chronic renal disease 6% vs 12 % vs 21%), intra-abdominal infections (14% vs 25% vs 37%), septic shock (12% vs 25% vs 36%) and organ dysfunctions, 2) higher 30 day mortality (6% vs 4% vs 17%) and fewer ICU free days (median 25 vs 23 vs 20), 3) more progression into CCI (22%, vs 34% vs 42%) with higher poor disposition discharge to non-home destinations (19% vs 40% vs 62%), 4) worse 12-month mortality (11% vs 14 % vs 33%) and, 5) poorer Zubrod Performance status and objectively-measured physical and cognitive functions with slight improvement over 12 month follow-up. Conclusion: Compared to younger patients, older sepsis survivors suffer with both a higher persistent disability burden and 12-month mortality.

Human thymic epithelial cells maintain long-term survival of clonogenic myeloid and erythroid progenitor cells in vitro

2000 ◽  
Vol 111 (1) ◽  
pp. 363-370 ◽  
Author(s):  
Katsuto Takenaka ◽  
Mine Harada ◽  
Tomoaki Fujisaki ◽  
Koji Nagafuji ◽  
Shinichi Mizuno ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Progenitor Cells ◽  
Thymic Epithelial Cells ◽  
Erythroid Progenitor ◽  
Term Survival ◽  
Long Term Survival ◽  
Erythroid Progenitor Cells

Clinical outcome and long-term survival following radical esophagectomy in the elderly

2001 ◽  
Vol 120 (5) ◽  
pp. A747-A748
Author(s):  
S DRESNER ◽  
A IMMMANUEL ◽  
P LAMB ◽  
S GRIFFIN
Keyword(s):  
Clinical Outcome ◽  
The Elderly ◽  
Radical Esophagectomy ◽  
Term Survival ◽  
Long Term Survival

1103: Long-Term Survival Following Nephrectomy for Renal Cell Carcinoma: The 15 Year UCLA Experience

2006 ◽  
Vol 175 (4S) ◽  
pp. 355-355
Author(s):  
Manuel Eisenberg ◽  
John S. Lam ◽  
Rakhee H. Goel ◽  
Allan J. Pantuck ◽  
Robert A. Figlin ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Term Survival ◽  
Long Term Survival
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