Neuropsychological Test Performance of Cognitively Healthy Centenarians: Normative Data From the Dutch 100-Plus Study

Nina Beker; Sietske A.M. Sikkes; Marc Hulsman; Ben Schmand; Philip Scheltens; Henne Holstege

doi:10.1111/jgs.15729

Neuropsychological test performance among healthy persons in northern India: development of normative data

Journal of NeuroVirology ◽

10.1007/s13365-015-0332-4 ◽

2015 ◽

Vol 21 (4) ◽

pp. 433-438 ◽

Cited By ~ 6

Author(s):

Drenna Waldrop-Valverde ◽

Raymond L. Ownby ◽

Deborah L. Jones ◽

Sunil Sharma ◽

Ritu Nehra ◽

...

Keyword(s):

Test Performance ◽

Normative Data ◽

Neuropsychological Test ◽

Northern India ◽

Healthy Persons

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P2-242: THE NEURO-NORMS CALCULATOR FOR OLDER ADULTS: DEMOGRAPHICALLY ADJUSTED NORMATIVE DATA AND STATISTICAL ANALYSIS OF NEUROPSYCHOLOGICAL TEST PERFORMANCE

Alzheimer s & Dementia ◽

10.1016/j.jalz.2014.05.919 ◽

2014 ◽

Vol 10 ◽

pp. P564-P565

Author(s):

Nicole A. Kochan ◽

John R. Crawford ◽

Melissa Jane Slavin ◽

Sarah Pont ◽

Henry Brodaty ◽

...

Keyword(s):

Older Adults ◽

Statistical Analysis ◽

Test Performance ◽

Normative Data ◽

Neuropsychological Test

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Behavior Rating Inventory of Executive Function Adult Version in Patients with Neurological and Neuropsychiatric Conditions: Symptom Levels and Relationship to Emotional Distress

Journal of the International Neuropsychological Society ◽

10.1017/s135561771600031x ◽

2016 ◽

Vol 22 (6) ◽

pp. 682-694 ◽

Cited By ~ 17

Author(s):

M. Løvstad ◽

S. Sigurdardottir ◽

S. Andersson ◽

V.A. Grane ◽

T. Moberget ◽

...

Keyword(s):

Executive Function ◽

Emotional Distress ◽

Test Performance ◽

Normative Data ◽

Rating Scales ◽

Neuropsychological Test ◽

Behavior Rating ◽

Behavior Rating Inventory ◽

And Performance ◽

The Relationship

AbstractObjectives:The present study explored the level of self-and informant reported executive functioning in daily living using the Behavior Rating Inventory of Executive Function-Adult Version (BRIEF-A) in a large sample comprising healthy adults and patient cohorts with neurological and neuropsychiatric disorders. The relationship to neuropsychological test performance and self-reported emotional distress was explored, as well as the applicability of U.S. normative data.Methods:Scores on the self- and informant reported BRIEF-A are presented, along with scores on standardized cognitive tests, and on rating scales of self-reported emotional distress in a Norwegian healthy comparison group (n=115), patients with severe traumatic brain injury (n=125), focal frontal lobe damage (n=29), focal cerebellar lesion (n=24), Parkinson’s disease (n=42), attention deficit hyperactivity disorder (n=34), type II bipolar disorder (n=21), and borderline personality disorder (n=18).Results:Strong associations were observed between the BRIEF-A and emotional distress in both the healthy group and in neurological groups, while no or weak relationships with IQ and performance-based tests of executive function were seen. The relationship between BRIEF-A and emotional distress was weaker in the neuropsychiatric patient groups, despite high symptom load in both domains. Healthy participants tended to have BRIEF-A scores 1/2–3/4SDbelow the U.S. normative mean ofTscore=50.Conclusions:The study demonstrates the need to interpret BRIEF-A results within a broad differential diagnostic context, where measures of psychological distress are included in addition to neuropsychological tests. Uncertainty about the appropriateness of U.S. normative data in non-U.S. countries adds to the need for interpretive caution. (JINS, 2016,22, 682–694)

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Neuropsychological Test Performance of Cognitively Healthy Centenarians: Normative data from the Dutch 100-plus Study

10.1101/366328 ◽

2018 ◽

Author(s):

Nina Beker ◽

Sietske A.M. Sikkes ◽

Marc Hulsman ◽

Ben Schmand ◽

Philip Scheltens ◽

...

Keyword(s):

Cognitive Functioning ◽

Test Performance ◽

Normative Data ◽

Neuropsychological Test ◽

Cognitive Testing ◽

Hearing Impairments ◽

Age Related ◽

Dementia Incidence ◽

Sensory Impairments ◽

Linear Regressions

ABSTRACTBackgroundThe population who reaches the extreme age of 100 years is growing. At this age, dementia incidence is high and cognitive functioning is variable and influenced by sensory impairments. Appropriate cognitive testing requires normative data generated specifically for this group. Currently, these are lacking. We set out to generate norms for neuropsychological tests in cognitively healthy centenarians while taking sensory impairments into account.MethodsWe included 235 centenarians (71.5% female) from the 100-plus Study, who self-reported to be cognitively healthy, which was confirmed by an informant and a trained researcher. Normative data were generated for 15 tests that evaluate global cognition, pre-morbid intelligence, attention, language, memory, executive and visuo-spatial functions by multiple linear regressions and/or percentiles. Centenarians with vision and/or hearing impairments were excluded for tests that required these faculties.ResultsSubjects scored on average 25.6±3.1 (range 17-30, interquartile-range 24-28) points on the MMSE. Vision problems and fatigue often complicated the ability to complete tests, and these problems explained 41% and 22% of the missing test scores respectively, whereas hearing problems (4%) and task incomprehension (6%) only rarely did. Sex and age showed a limited association with test performance, whereas educational level was associated with performance on the majority of the tests.ConclusionsNormative data for the centenarian population is provided, while taking age-related sensory impairments into consideration. Results indicate that, next to vision impairments, fatigue and education level should be taken into account when assessing cognitive functioning in centenarians.

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Online Self-Administered Cognitive Testing Using the Amsterdam Cognition Scan: Establishing Psychometric Properties and Normative Data (Preprint)

10.2196/preprints.9298 ◽

2017 ◽

Author(s):

Heleen EM Feenstra ◽

Ivar E Vermeulen ◽

Jaap MJ Murre ◽

Sanne B Schagen

Keyword(s):

Psychometric Properties ◽

Test Performance ◽

Normative Data ◽

Large Scale ◽

Neuropsychological Test ◽

Intraclass Correlation ◽

Correlation Coefficients ◽

Computer Skills ◽

Repeated Measurements ◽

Cognitive Testing

BACKGROUND Online tests enable efficient self-administered assessments and consequently facilitate large-scale data collection for many fields of research. The Amsterdam Cognition Scan is a new online neuropsychological test battery that measures a broad variety of cognitive functions. OBJECTIVE The aims of this study were to evaluate the psychometric properties of the Amsterdam Cognition Scan and to establish regression-based normative data. METHODS The Amsterdam Cognition Scan was self-administrated twice from home—with an interval of 6 weeks—by 248 healthy Dutch-speaking adults aged 18 to 81 years. RESULTS Test-retest reliability was moderate to high and comparable with that of equivalent traditional tests (intraclass correlation coefficients: .45 to .80; .83 for the Amsterdam Cognition Scan total score). Multiple regression analyses indicated that (1) participants’ age negatively influenced all (12) cognitive measures, (2) gender was associated with performance on six measures, and (3) education level was positively associated with performance on four measures. In addition, we observed influences of tested computer skills and of self-reported amount of computer use on cognitive performance. Demographic characteristics that proved to influence Amsterdam Cognition Scan test performance were included in regression-based predictive formulas to establish demographically adjusted normative data. CONCLUSIONS Initial results from a healthy adult sample indicate that the Amsterdam Cognition Scan has high usability and can give reliable measures of various generic cognitive ability areas. For future use, the influence of computer skills and experience should be further studied, and for repeated measurements, computer configuration should be consistent. The reported normative data allow for initial interpretation of Amsterdam Cognition Scan performances.

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Posttraumatic Stress Disorder Exacerbates Emotional Complaints but not Cognitive Impairments in Individuals Suffering from Postconcussional Disorder after Mild Traumatic Brain Injury

Zeitschrift für Neuropsychologie ◽

10.1024/1016-264x/a000132 ◽

2015 ◽

Vol 26 (1) ◽

pp. 35-50 ◽

Cited By ~ 1

Author(s):

Sara C. Schroeder ◽

Ronald M. Ruff ◽

Lutz Jäncke

Keyword(s):

Traumatic Brain Injury ◽

Posttraumatic Stress Disorder ◽

Brain Injury ◽

Posttraumatic Stress ◽

Mild Traumatic Brain Injury ◽

Test Performance ◽

Stress Disorder ◽

Negative Impact ◽

Neuropsychological Test ◽

Composite Scale

The aim of this study was to examine the effect of posttraumatic stress disorder (PTSD) on (a) neuropsychological test performance and (b) self-reported emotional complaints within individuals suffering from postconcussional disorder (PCD) after a mild traumatic brain injury (MTBI). A two-group comparative research design was employed. Two MTBI samples with and without PTSD were assessed with a neuropsychological test battery and the Ruff Neurobehavioral Inventory (RNBI). On the neurocognitive test performances no significant between group differences were found, but the MTBI group with PTSD endorsed a significantly greater number of emotional complaints, especially in the RNBI subscales of anxiety and depression. The patients with PTSD also endorsed a significantly greater number of premorbid sequelae in the RNBI emotional composite scale as well as the RNBI premorbid subscales of pain, anxiety and abuse. In sum, PTSD has a negative impact on emotional but not cognitive functioning within individuals suffering from PCD after a mild TBI.

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