Cognition and Vitamin D in Older African-American Women- Physical performance and Osteoporosis prevention with vitamin D in older African Americans Trial and Dementia

2018 ◽  
Vol 67 (1) ◽  
pp. 81-86 ◽  
Author(s):  
Jeanette E. Owusu ◽  
Shahidul Islam ◽  
Subhashini S. Katumuluwa ◽  
Alexandra R. Stolberg ◽  
Gianina L. Usera ◽  
...  
2019 ◽  
Vol 6 (9) ◽  
Author(s):  
John F Aloia ◽  
Shahidul Islam ◽  
Mageda Mikhail

Abstract Background There is considerable heterogeneity in clinical trials examining the role of vitamin D in the prevention of acute respiratory infections (ARIs). Methods The primary aim of the Physical Performance, Osteoporosis, and Vitamin D in Older African-American Women (PODA) trial was the prevention of bone loss and decline in physical performance. A questionnaire about ARIs was administered every 3 months for 3 years to 260 black American women in a double-blind randomized clinical trial that had a placebo group and a vitamin D supplementation group. The serum 25(OH)D level was maintained >30 ng/mL in the vitamin D group. Results Serum 25(OH)D was maintained >30 ng/mL in 90% of the active group, whereas levels approximated those associated with the recommended dietary allowance (20 ng/mL) in the placebo group. There was no difference in occurrence of ARIs in the treatment group vs the placebo group. ARIs were not related to total or free 25(OH)D, which were measured at baseline and annually for 36 months. Conclusions Vitamin D supplementation sufficient to maintain serum 25(OH)D >30 ng/mL does not prevent ARIs in older African American women. ClinicalTrials.gov Registration Number NCT01153568.


2011 ◽  
Vol 2011 ◽  
pp. 1-8 ◽  
Author(s):  
Brooke C. Schneider ◽  
Peter A. Lichtenberg

An older adult's ability to perform physical tasks is predictive of disability onset and is associated with declines in cognition. Risk factors for physical performance declines among African Americans, a group with the highest rates of disability, remain understudied. This study sought to identify demographic, health, and cognitive factors associated with lower-extremity physical performance in a sample of 106 African American women ages 56 to 91. After controlling for global cognitive functioning (Mini Mental State Exam), physical performance was associated with executive functioning (Stroop Color/Word), but not visuospatial construction (WASI Block Design) or processing speed (Trail Making Test, Part A). Executive functioning remained associated with physical performance after entry of demographic variables, exercise, depression, disease burden, and body mass index (BMI). Age, and BMI were also significant in this model. Executive functioning, age and BMI are associated with lower-extremity physical performance among older African American women.


2013 ◽  
Vol 98 (3) ◽  
pp. 1137-1146 ◽  
Author(s):  
J. Christopher Gallagher ◽  
Munro Peacock ◽  
Vinod Yalamanchili ◽  
Lynette M. Smith

2019 ◽  
Vol 67 (5) ◽  
pp. 1043-1049 ◽  
Author(s):  
John F. Aloia ◽  
Rakhil Rubinova ◽  
Melissa Fazzari ◽  
Shahidul Islam ◽  
Mageda Mikhail ◽  
...  

2018 ◽  
Vol 65 ◽  
pp. 39-45 ◽  
Author(s):  
Ruban Dhaliwal ◽  
Mageda Mikhail ◽  
Gianina Usera ◽  
Alexandra Stolberg ◽  
Shahidul Islam ◽  
...  

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Ruban Dhaliwal ◽  
Mageda Mikhail ◽  
Jeanette Owusu ◽  
Subhashini Katumuluwa ◽  
Shahidul Islam ◽  
...  

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