Neutrophil to Lymphocyte Ratio As a Risk Stratification Tool for Older Adults with Pneumonia

2017 ◽  
Vol 66 (2) ◽  
pp. 417-418 ◽  
Author(s):  
Stamatis Karakonstantis ◽  
Dimitra Kalemaki
2017 ◽  
Vol 66 (2) ◽  
pp. 418-420
Author(s):  
Emanuela Cataudella ◽  
Chiara M. Giraffa ◽  
Salvatore Di Marca ◽  
Alfredo Pulvirenti ◽  
Benedetta Stancanelli ◽  
...  

2007 ◽  
Vol 55 (8) ◽  
pp. 1269-1274 ◽  
Author(s):  
Fredric M. Hustey ◽  
Lorraine C. Mion ◽  
Jason T. Connor ◽  
Charles L. Emerman ◽  
James Campbell ◽  
...  

2018 ◽  
Vol 28 (1) ◽  
pp. 23-27 ◽  
Author(s):  
T. Corriere ◽  
S. Di Marca ◽  
E. Cataudella ◽  
A. Pulvirenti ◽  
S. Alaimo ◽  
...  

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 595-595
Author(s):  
Jennifer Woodward ◽  
Tru Byrnes

Abstract Delirium is a disturbance of attention accompanied by a change in baseline cognition that is commonly seen in acute care settings, and effects up to 80% of ICU patients. The development of delirium has adverse effects on patient outcomes and high health care costs. Of patients aged 65+ admitted to our hospital in 2019, non-delirious patients had a five-day length of stay (LOS) compared to a 10-14 days LOS in delirious patients. A five days LOS increase adds an additional $ 8,325 per patient for an extra annual cost of 15 million dollars. Additionally, delirium is often not recognized. A prior retrospective study showed that 31% of older adults seen by a Geriatrics provider were diagnosed with delirium, while only 11% were detected by nurse’s CAM screen. Given the need to improve delirium detection and management, a QI project was undertaken with a goal to recruit an interdisciplinary team, create a risk stratification tool to identify patients at substantial risk for developing delirium, and develop a delirium prevention protocol. Patients with a score of ≥ 4 were initiated on a nurse driven delirium protocol that included a delirium precaution sign and caregiver education. 6 months data has shown increased delirium detection of 33%, a reduction in 7.7 days LOS, reduced SNF discharge by 27%, and a significant LOS saving of 231 days. The results were statistically significant, p < 0.04 for LOS reduction. The cost avoidance in LOS alone were $384,615 for delirium patients.


2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Lukas Müller ◽  
Aline Mähringer-Kunz ◽  
Florian Jungmann ◽  
Yasemin Tanyildizi ◽  
Fabian Bartsch ◽  
...  

Background. In addition to the clinical parameters, immune-inflammatory markers have emerged as prognostic factors in patients with advanced biliary tract cancer (ABC). The recently proposed A.L.A.N. score combines both in an easily applicable manner. The aim of this study was to perform the first external evaluation of this score. Methods. All patients from our clinical registry unit who had unresectable ABC underwent first-line chemotherapy from 2006 to 2018 and met the inclusion criteria of the original study were included (n =  74). The A.L.A.N. score comprises the following parameters: actual neutrophil count, lymphocyte-to-monocyte ratio, albumin, and neutrophil-to-lymphocyte ratio (A.L.A.N.). Univariate and multivariate hazard regression analyses were performed to evaluate the score’s parameters regarding overall survival (OS). The concordance index (C-index) and integrated Brier score (IBS) were calculated to evaluate the score’s predictive performance. Results. Low, intermediate, and high A.L.A.N. scores corresponded to median OS of 21.9, 11.4, and 4.3 months, respectively, resulting in a significant risk stratification (log-rank p=0.017). In multivariate analysis, a high-risk A.L.A.N. score remained an independent predictor of poor survival (p=0.016). Neutrophil-to-lymphocyte ratio was not a significant factor for poor OS in the analyses in the cohort. The score’s ability to predict individual patient survival was only moderate with a C-index of 0.63. Conclusions. The A.L.A.N. score can be used to identify risk groups with a poor prognosis prior to the start of chemotherapy. However, the ability of the score to predict individual patient outcome was only moderate; thus, it may only serve as a minor component in the complex interdisciplinary discussion.


2015 ◽  
Vol 115 (1) ◽  
pp. 57-61 ◽  
Author(s):  
Vicente A. Benites-Zapata ◽  
Adrian V. Hernandez ◽  
Vijaiganesh Nagarajan ◽  
Clay A. Cauthen ◽  
Randall C. Starling ◽  
...  

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