scholarly journals Effect of Rehabilitation on Recovery of Sympathetic Nervous Activity Measured According to Heart Rate Variability in Frail Elderly Adults

2016 ◽  
Vol 64 (9) ◽  
pp. e15-e16 ◽  
Author(s):  
Koji Shibasaki ◽  
Shizuru Yamada ◽  
Yasuyoshi Ouchi ◽  
Masahiro Akishita ◽  
Sumito Ogawa
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Frail Elderly ◽  
Nervous Activity ◽  
Sympathetic Nervous Activity ◽  
Elderly Adults ◽  
Sympathetic Nervous

Heart Rate Variability During Early Mobilization in Patients with Acute Ischemic Stroke

2018 ◽  
Vol 80 (1-2) ◽  
pp. 50-54 ◽  
Author(s):  
Masafumi Nozoe ◽  
Miho Yamamoto ◽  
Miki Kobayashi ◽  
Masashi Kanai ◽  
Hiroki Kubo ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Nervous Activity ◽  
Early Mobilization ◽  
Sympathetic Nervous Activity ◽  
Parasympathetic Nerve ◽  
Significant Difference ◽  
Sympathetic Nervous

Autonomic dysfunction is one of the predictors of poor outcome in patients with acute ischemic stroke. We compared the heart rate variability (HRV) during early mobilization in patients with or without neurological deterioration (ND). We enrolled 7 acute ischemic patients with ND and 14 without ND and measured their HRV in the rest and mobilization by electrocardiography. There was a significant difference in sympathetic nervous activity during mobilization between the 2 groups. However, no significant differences in blood pressure, heart rate, and parasympathetic nerve activity were observed. In patients with acute ischemic stroke, it is likely that the increase in sympathetic nervous activity during mobilization is associated with ND.

Intradermal Acupuncture on Shen-Men and Nei-Kuan Acupoints Improves Insomnia in Stroke Patients by Reducing the Sympathetic Nervous Activity: A Randomized Clinical Trial

2009 ◽  
Vol 37 (06) ◽  
pp. 1013-1021 ◽  
Author(s):  
Seung Yeop Lee ◽  
Yong Hyeon Baek ◽  
Seong Uk Park ◽  
Sang Kwan Moon ◽  
Jung Mi Park ◽  
...  
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Controlled Trial ◽  
Nervous Activity ◽  
Sham Acupuncture ◽  
Acupuncture Group ◽  
Sympathetic Nervous Activity ◽  
Stroke Patients ◽  
Double Blind ◽  
Intradermal Acupuncture

This study is a double-blind randomized controlled trial on the effect of intradermal acupuncture on insomnia after stroke. Hospitalized stroke patients with insomnia were enrolled in the study and were randomly assigned to either a real intradermal acupuncture group (RA group) or a sham acupuncture group (SA group). The RA group received intradermal acupuncture on Shen-Men (He-7) and Nei-Kuan (EH-6) for three days, and the SA group received sham acupuncture on the same points. The effect of acupuncture on insomnia was measured using Insomnia Severity Index (ISI) and Athens Insomnia Scale (AIS) at baseline and three days after treatment. To assess the effect of acupuncture on the autonomic nervous function, the subjects' blood pressure and heart rate variability were monitored. Fifty-two subjects (27 in the RA group and 25 in the SA group) were included in the final analysis. The insomnia-related scales ISI and AIS showed greater improvement of insomnia in the RA group than in the SA group. Moreover, there is a greater reduction of the number of non-dippers and a greater decrease of the LF/HF ratio (heart rate variability) in the RA group than in the SA group. These results indicate that sympathetic hyperactivities were stabilized in the RA group. It can thus be concluded that intradermal acupuncture on Shen-Men and Nei-Kuan is a useful therapeutic method for post stroke-onset insomnia as it reduces sympathetic hyperactivities.

Abstract 5430: Obstructive Sleep Apnoea Exacerbates Muscular Sympathetic Nervous Activity in Patients with Metabolic Syndrome

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Ivani C Trombetta ◽  
Cristiane M Nunes ◽  
Luciano F Drager ◽  
Raffael F Fraga ◽  
Maria Janieire N Alves ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Heart Rate ◽  
Oxygen Saturation ◽  
Obstructive Sleep Apnoea ◽  
Nervous Activity ◽  
Sleep Apnoea ◽  
Sympathetic Nervous Activity ◽  
Obstructive Sleep ◽  
Sympathetic Nervous

Obstructive sleep apnoea (OSA) and metabolic syndrome (MetS) independently increases muscular sympathetic nervous activity (MSNA). Unknown is whether OSA has an additive effect on MSNA in patients with MetS. We tested the hypothesis that: OSA would have an additive effect on MSNA in patients with MetS. In addition, we studied whether the increase in MSNA in patients with MetS is associated with alteration in arterial baroreflex sensitivity (BRS). Twenty four patients with MetS diagnosed according ATP-III were divided in two groups: MetS+OSA (n=14) and MetS (n=10). They were matched for age, body mass index, waist circumference, and metabolic profile: OSA was defined by an apnoea/hypopnoea index (AHI)>15 events/hour by polysonography. MSNA was recorded directly from the peroneal nerve using the technique of microneurography. Blood pressure (BP) was monitored on a beat-by-beat basis (Finapress) and heart rate by ECG. BRS was analyzed by spontaneous BP and heart rate fluctuations. AHI was higher (42±9 vs. 7±1 events/h, P =0.0001) and minimum oxygen saturation lower (77±2 vs. 87±1 %, P =0.001) in MetS+OSA patients. Patients MetS+OSA had higher MSNA (55±3 vs. 43±2 bursts/100 beats, P =0.01) and systolic BP (158±4 vs.144±3 mmHg, P =0.01) when compared with patients with MetS without OSA. Further analysis showed that AHI and minimum oxygen saturation have significant correlation with MSNA (r=0.65; P =0.001 and r=−0.48; P =0.017, respectively). Patients with MetS+OSA had lower BRS for increases (7.8±0.9 vs. 13.4 ± 1.4 msec/mmHg, P =0.01) and decreases (7.2±0.9 vs. 13.2 ± 2.0 msec/mmHg, P =0.03) in blood pressure than patients with MetS without OSA. MSNA significantly correlated with BRS during spontaneous increases in blood pressure (r=−0.56, P =0.01). OSA exacerbates MSNA in patients with MetS. In addition, the augmented MSNA in patients with MetS+OSA is associated with reduced BRS. These findings suggest that OSA increases the risk for cardiovascular disease in patients with MetS.

Favorable Effect of Sympathetic Nervous Activity on Rehabilitation Outcomes in Frail Elderly

2015 ◽  
Vol 16 (9) ◽  
pp. 799.e7-799.e12 ◽  
Author(s):  
Koji Shibasaki ◽  
Sumito Ogawa ◽  
Shizuru Yamada ◽  
Katsuya Iijima ◽  
Masato Eto ◽  
...  
Keyword(s):  
Frail Elderly ◽  
Nervous Activity ◽  
Favorable Effect ◽  
Sympathetic Nervous Activity ◽  
Rehabilitation Outcomes ◽  
Sympathetic Nervous

Postprandial Sympatho-Adrenal Activity: Its Relation to Metabolic and Cardiovascular Events and to Changes in Meal Frequency

1995 ◽  
Vol 89 (4) ◽  
pp. 349-357 ◽  
Author(s):  
Mario Vaz ◽  
Andrea Turner ◽  
Bronwyn Kingwell ◽  
Jaye Chin ◽  
Elizabeth Koff ◽  
...  
Keyword(s):  
Heart Rate ◽  
Cardiovascular Events ◽  
Peak Plasma ◽  
Nervous Activity ◽  
Systolic Pressure ◽  
Plasma Noradrenaline ◽  
Whole Body ◽  
Sympathetic Nervous Activity ◽  
Insulin Levels ◽  
Sympathetic Nervous

1. Sympatho-adrenal activity was measured after the consumption of a 3.15 MJ mixed meal. Whole-body noradrenaline spillover rates, forearm plasma noradrenaline spillover and adrenaline secretion rates were derived using isotope dilution methodology. Heart rate and blood pressure spectral analysis measurements were also made. The relation of sympatho-adrenal activity to thermogenic and cardiovascular events was studied. Sympathetic nervous and thermogenic responses were measured for 120 min after the single 3.15 MJ meal and compared with those after three 1.05 MJ meals, given 30 min apart. 2. Whole-body and forearm plasma noradrenaline spillover, and the 0.1 Hz component of systolic pressure power all increased significantly postprandially, while the 0.1 Hz component of heart rate variability, an indirect index of cardiac sympathetic nervous activity, remained unaltered. Adrenaline secretion was unaltered postprandially. Whole-body plasma noradrenaline spillover and thermogenesis during the 120 min postprandial period were 37% and 36% higher after the single meal as compared with the multiple meals, although this was not statistically significant. 3. The sympathetic neural responses were delayed in relation to peak plasma insulin levels and sustained in the face of declining insulin levels. Energy expenditure increased significantly postprandially, but there was no direct quantitative relationship to plasma noradrenaline spillover. Forearm oxygen consumption did not increase postprandially despite significant increases in regional noradrenaline spillover. Thus, no close relation was demonstrated between postprandial sympathetic nervous activation and either insulin secretion or thermogenesis.

Noradrenaline Kinetics and Coronary Haemodynamics during Acute β1-Adrenoceptor Blockade in Man

1993 ◽  
Vol 84 (4) ◽  
pp. 413-417 ◽  
Author(s):  
Alastair J. McCance ◽  
J. Colin Forfar
Keyword(s):  
Heart Rate ◽  
Blood Flow ◽  
Nervous Activity ◽  
Whole Body ◽  
Sympathetic Nervous Activity ◽  
Coronary Vascular Resistance ◽  
Diagnostic Cardiac Catheterization ◽  
Sympathetic Nervous ◽  
Arterial Plasma ◽  
Coronary Sinus Blood

1. To investigate the effects of acute β1-adrenoceptor blockade on sympathetic nervous activity, cardiac and whole-body noradrenaline kinetics were determined during intravenous infusions of saline placebo and of metoprolol (10-15 mg plus 150 μg min−1 kg−1) in 10 patients undergoing diagnostic cardiac catheterization, in whom β-adrenoceptor antagonists had been discontinued for 7 days. 2. Coronary haemodynamics were measured in these 10 patients plus two others. Compared with saline placebo, metoprolol administration was associated with decreases in heart rate (68 ± 2 to 59 ± 3 beats/min, P < 0.001) and coronary sinus blood flow (86 ± 8 to 68 ± 6 ml/min, P < 0.001) and an increase in calculated coronary vascular resistance (1.42 ± 0.19 to 1.75 ± 0.22 mmHg min ml−1, P < 0.001). Arterial and femoral venous noradrenaline concentrations, whole-body noradrenaline clearance and whole-body noradrenaline spillover to arterial plasma did not change. In contrast, cardiac noradrenaline spillover (33.7 ± 5.1 to 20.2 ± 4.3 pmol/min, P < 0.05) and cardiac noradrenaline clearance (31 ± 3 to 23 ± 3 ml/min, P < 0.001) were significantly decreased during metoprolol administration. 3. These results may be explained by inhibition of pre-junctional facilitatory β-adrenoceptors, which we hypothesize may be predominantly of the β1-subtype in the heart and of the β2-subtype in the periphery.

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