scholarly journals Response of Vitamin D Concentration to Vitamin D3 Administration in Older Adults without Sun Exposure: A Randomized Double-Blind Trial

2016 ◽  
Vol 64 (1) ◽  
pp. 65-72 ◽  
Author(s):  
Janice B. Schwartz ◽  
Lynn Kane ◽  
Daniel Bikle
Keyword(s):  
Older Adults ◽  
Vitamin D ◽  
Vitamin D3 ◽  
Sun Exposure ◽  
Double Blind Trial ◽  
Double Blind ◽  
Blind Trial

Research shows that highly potent vaccine reduces the burden of herpes zoster and the incidence of postherpetic neuralgia in older adults

2005 ◽  
Vol 10 (23) ◽  
Author(s):  
B C Ciancio
Keyword(s):  
Older Adults ◽  
Herpes Zoster ◽  
Postherpetic Neuralgia ◽  
Double Blind Trial ◽  
Double Blind ◽  
Live Attenuated Vaccine ◽  
Blind Trial ◽  
Attenuated Vaccine

A live attenuated vaccine reduces the burden of herpes zoster (shingles) in older adults, according to the recently published results of a randomised, double-blind trial

Effects of an Iron or Iron and Vitamin D–Fortified Flavored Skim Milk on Iron Metabolism: A Randomized Controlled Double-Blind Trial in Iron-Deficient Women

2013 ◽  
Vol 32 (5) ◽  
pp. 312-320 ◽  
Author(s):  
Laura Toxqui ◽  
Ana M. Pérez-Granados ◽  
Ruth Blanco-Rojo ◽  
Ione Wright ◽  
Carmen González-Vizcayno ◽  
...  
Keyword(s):  
Vitamin D ◽  
Iron Metabolism ◽  
Skim Milk ◽  
Double Blind Trial ◽  
Double Blind ◽  
Blind Trial ◽  
Randomized Controlled ◽  
Iron Deficient

scholarly journals Vitamin D supplementation and calcium absorption during caloric restriction: a randomized double-blind trial

2013 ◽  
Vol 97 (3) ◽  
pp. 637-645 ◽  
Author(s):  
Sue A Shapses ◽  
Deeptha Sukumar ◽  
Stephen H Schneider ◽  
Yvette Schlussel ◽  
Robert M Sherrell ◽  
...  
Keyword(s):  
Vitamin D ◽  
Caloric Restriction ◽  
Calcium Absorption ◽  
Vitamin D Supplementation ◽  
Double Blind Trial ◽  
Double Blind ◽  
Blind Trial

scholarly journals Prevention of bone loss by vitamin D supplementation in elderly women: a randomized double-blind trial.

1995 ◽  
Vol 80 (4) ◽  
pp. 1052-1058 ◽  
Author(s):  
M E Ooms ◽  
J C Roos ◽  
P D Bezemer ◽  
W J van der Vijgh ◽  
L M Bouter ◽  
...  
Keyword(s):  
Vitamin D ◽  
Bone Loss ◽  
Elderly Women ◽  
Vitamin D Supplementation ◽  
Double Blind Trial ◽  
Double Blind ◽  
Blind Trial ◽  
Prevention Of Bone Loss

scholarly journals Vitamin D Synthesis Following a Single Bout of Sun Exposure in Older and Younger Men and Women

Nutrients ◽  
2020 ◽  
Vol 12 (8) ◽  
pp. 2237 ◽  
Author(s):  
Jenna R. Chalcraft ◽  
Linda M. Cardinal ◽  
Perry J. Wechsler ◽  
Bruce W. Hollis ◽  
Kenneth G. Gerow ◽  
...  
Keyword(s):  
Older Adults ◽  
Vitamin D ◽  
Vitamin D3 ◽  
Ex Vivo ◽  
Sun Exposure ◽  
Vitamin D Metabolites ◽  
Post Exposure ◽  
Non Melanoma Skin Cancer ◽  
Younger Men ◽  
Cutaneous Synthesis

Older adults are frequently cited as an at-risk population for vitamin D deficiency that may in part be due to decreased cutaneous synthesis, a potentially important source of cholecalciferol (vitamin D3). Previous studies found that cutaneous D3 production declines with age; however, most studies have been conducted ex vivo or in the photobiology lab. The purpose of this study was to characterize the response of vitamin D metabolites following a 30-min bout of sun exposure (15-min each to the dorsal and ventral sides) at close to solar noon in younger and older adults. Methods: 30 healthy individuals with skin type II/III were recruited; a younger cohort, aged 20–37 (n = 18) and an older cohort (n = 12), age 51–69 years. Exposure was at outer limits of sensible sun exposure designed to enhance vitamin D synthesis without increasing risk of photo ageing and non-melanoma skin cancer. Serum D3 concentration was measured at baseline, 24, 48 and 72 h post-exposure. Serum 25(OH)D was measured at baseline and 72 h post-exposure plus 168 h post-exposure in the older cohort. Results: D3 increased in response to sun exposure (time effect; p = 0.002) with a trend for a difference in D3 between cohorts (time*group; p = 0.09). By regression modeling of continuous data, age accounted for 20% of the variation in D3 production. D3 production decreased by 13% per decade. Despite changes in D3, however, serum 25(OH)D did not change from baseline to 72 or 168 h post exposure (p > 0.10). Conclusions: Serum D3 concentration increased significantly in response to outdoor sun exposure in younger and older adults. While ageing may dampen cutaneous synthesis, sunlight exposure is still a significant source of vitamin D3.

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