Renal Dysfunction Contributes to Episodic Memory Deficits and Medial Temporal Atrophy in Alzheimer's Disease: A Pilot Study

2014 ◽  
Vol 62 (10) ◽  
pp. 1981-1982 ◽  
Author(s):  
Aloysius Ng ◽  
Yasmin Idu Jion ◽  
Nur Hani Zainal ◽  
Nagaendran Kandiah
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Pilot Study ◽  
Episodic Memory ◽  
Renal Dysfunction ◽  
Memory Deficits

Depression does not aggravate the episodic memory deficits associated with Alzheimer's disease.

1999 ◽  
Vol 13 (4) ◽  
pp. 532-538 ◽  
Author(s):  
Kjell Fahlander ◽  
Anna-Karin Berger ◽  
Åke Wahlin ◽  
Lars Bäckman
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Episodic Memory ◽  
Memory Deficits

scholarly journals Applying New Research Criteria for Diagnosis of Early Alzheimer's Disease: Sex and Intelligence Matter

2009 ◽  
Vol 2009 ◽  
pp. 1-6 ◽  
Author(s):  
U. Beinhoff ◽  
H. Tumani ◽  
M. W. Riepe
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Episodic Memory ◽  
Memory Function ◽  
Memory Deficits ◽  
Intellectual Ability ◽  
Neurodegenerative Process ◽  
Using Data ◽  
New Research ◽  
Research Criteria

Alzheimer's disease (AD) can be diagnosed according to new research criteria proposed recently (Dubois et al., 2007). Diagnosis is made on grounds of episodic memory deficits and one pathological biomarker: cerebrospinal fluid (CSF) or structural/functional imaging. Goal was to investigate the dependence of episodic memory function on material (verbal, visuospatial), gender and premorbid intellectual ability (IQ). The new research criteria of AD were applied retrospectively using data of 68 patients (Mini-Mental-Status Examination, MMSE 22) from a university memory clinic. Women with lower IQ performed worse on visuospatial episodic memory than women with higher IQ and men with the same IQ. Thus, women with lower IQ appear to be particularly vulnerable tovisuospatialepisodic memory deficits despite similar CSF tau values indicating a similar activity of the neurodegenerative process. Gender, premorbid IQ, and visuospatial material need to be considered in the assessment of episodic memory breakdown applying the newly proposed research criteria for the diagnosis of AD.

[P4-158]: PRE-SCREENING FOR EPISODIC MEMORY DEFICITS CAN ENRICH FOR ELIGIBLE SUBJECTS IN EARLY ALZHEIMER's DISEASE CLINICAL TRIALS

2017 ◽  
Vol 13 (7S_Part_27) ◽  
pp. P1319-P1320
Author(s):  
Rosemary A. Abbott ◽  
Francesca K. Cormack ◽  
Sebastiaan Engelborghs ◽  
Maarten Timmers ◽  
Christopher Randolph ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Clinical Trials ◽  
Episodic Memory ◽  
Memory Deficits ◽  
Early Alzheimer’S Disease

Impact of Comorbid Depression on Serial Position Effects in Alzheimer’s Disease

GeroPsych ◽  
2014 ◽  
Vol 27 (4) ◽  
pp. 161-169 ◽  
Author(s):  
Nienke A. Hofrichter ◽  
Sandra Dick ◽  
Thomas G. Riemer ◽  
Carsten Schleussner ◽  
Monique Goerke ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Serial Position ◽  
Episodic Memory ◽  
Memory Performance ◽  
Memory Function ◽  
Word List ◽  
Position Effects ◽  
Serial Position Effects ◽  
List Memory

Hippocampal dysfunction and deficits in episodic memory have been reported for both Alzheimer’s disease (AD) and major depressive disorder (MDD). Primacy performance has been associated with hippocampus-dependent episodic memory, while recency may reflect working memory performance. In this study, serial position profiles were examined in a total of 73 patients with MDD, AD, both AD and MDD, and healthy controls (HC) by means of CERAD-NP word list memory. Primacy performance was most impaired in AD with comorbid MDD, followed by AD, MDD, and HC. Recency performance, on the other hand, was comparable across groups. These findings indicate that primacy in AD is impaired in the presence of comorbid MDD, suggesting additive performance decrements in this specific episodic memory function.

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