scholarly journals Intensive Weight Loss Intervention in Older Individuals: Results from the Action for Health in Diabetes Type 2 Diabetes Mellitus Trial

2013 ◽  
Vol 61 (6) ◽  
pp. 912-922 ◽  
Author(s):  
Mark A. Espeland ◽  
W. Jack Rejeski ◽  
Delia S. West ◽  
George A. Bray ◽  
Jeanne M. Clark ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Weight Loss ◽  
Type 2 Diabetes Mellitus ◽  
Diabetes Type 2 ◽  
Diabetes Type ◽  
Weight Loss Intervention ◽  
Older Individuals

Dynamics of exchange parameters of hormonal indicators in patients with climacteric syndrome associated with diabetes type 2 under the influence of complex therapy with application of antihomotoxicological agents

2018 ◽  
pp. 36-39
Author(s):  
M.O. Pavlovska ◽  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Diabetes Type 2 ◽  
Diabetes Type ◽  
Point Of View ◽  
Climacteric Syndrome ◽  
Basic Therapy ◽  
Complex Therapy

The objective: was to compare the efficacy of complex methods of treating climacteric syndrome in patients with concomitant type 2 diabetes mellitus (DM) by analyzing hormonal parameters before and after complex therapy using antihomotoxicological drugs. Materials and methods. We examined 58 patients aged 45-55 years with a climacteric syndrome on the background of a 2-type diabetes mellitus. Women of the 1st group (n = 28) received only basic therapy according to the National Consensus for the management of patients in menopause with concomitant DM of type 2. Women of the 2nd group (n = 30) were treated with antihomotoxicological drugs against the background of basic therapy. Results. The proposed complexes positively influenced the hormonal state of patients, and also reduced the severity of climacteric syndrome and psychoemotional component. More effective was a complex that included antihomotoxicological agents, which is confirmed by the dynamics of hormonal parameters. Conclusion. From the clinical point of view, the obtained results give grounds to recommend these complexes for the correction of hormonal disorders in women with menopausal disorders on the background of type 2 diabetes mellitus. Key words: climacteric syndrome, diabetes type 2, base therapy, antihomotoxicological agents.

scholarly journals Diabetes Mellitus Tipo 2: A importância do diagnóstico precoce da diabetes / Type 2 Diabetes Mellitus: The importance of early diabetes diagnosis

2021 ◽  
Vol 7 (12) ◽  
pp. 116526-116551
Author(s):  
Ygor Riquelme Antunes ◽  
Elielson Mendonça De Oliveira ◽  
Leonardo Aguiar Pereira ◽  
Maria Francisca Pimenta Picanço
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Diabetes Type 2 ◽  
Diabetes Type ◽  
Diabetes Diagnosis ◽  
Early Diabetes

Evaluation of Knee Proprioception and Kinesthesia in Patients with Type 2 Diabetes Mellitus

2014 ◽  
Author(s):  
Amin Kordi yoosefinejad ◽  
Farzaneh Moslemi Haghighi
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Diabetes Type 2 ◽  
Diabetes Type ◽  
Healthy People ◽  
Sensory Function ◽  
Muscle Testing ◽  
Patients With Diabetes

Background: Diabetes is a highly significant public health problem inIran with a prevalence of 5 to 8%. Proprioception plays an important role in the orientation and limb movement in space. Diabetic neuropathy decreases sensory function and causes gait instabilities.Objective: The present study evaluated knee proprioception and kinesthesia in patients with type 2 diabetes with and without neuropathy and compared the results with those of healthy people. Methods: The subjects were ten type 2 diabetes mellitus patients with diabetes type 2 associated with neuropathy, ten patients with diabetes without neuropathy and ten healthy people as the control group. Data were collected in a physical examination and using a questionnaire. Special tests included manual muscle testing of the knee musculature, Achilles and patellar reflexes, and knee proprioception and kinesthesia. Data were analyzed using one-way ANOVA and the Tukey test.Results: the results show that knee proprioception and kinesthesia were significantly decreased in patients with diabetes mellitus type 2 in comparison with healthy people and there was a greater decline in patients with diabetes associated with neuropathy than in patients with diabetes without neuropathy. Also, knee musculature strength was significantly lower in patients with diabetes in comparison with healthy people and the attenuation was greater in neuropathic patients than in non-neuropathic ones. Conclusions: Patients with diabetes type 2 especially those with neuropathy suffer from proprioception deficits. Proprioception training may prevent secondary problems occurring as a result of proprioception impairment in patients with diabetes type2.

scholarly journals FINDRISK and occupation: need of prevention of diabetes type 2 at the workplace

2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
K Lyubomirova ◽  
M Tabanska ◽  
L Hristova ◽  
M Samuneva ◽  
M Yancheva ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Cardiovascular Risk ◽  
Older Workers ◽  
Significant Proportion ◽  
Diabetes Type 2 ◽  
Diabetes Type ◽  
Increased Risk

Abstract Background Diabetes mellitus is a risk factor for atherosclerosis, cardiovascular morbidity and increased mortality. Identifying people at a high risk of developing diabetes determine the prognosis and quality of life of the patients and prevent the development of macrovascular complications of diabetes. Within the framework of an international project, the ten-year risk of developing type 2 diabetes mellitus in two age groups workers (up to 25 and over 55) of four economic sectors (construction, clothing, hairdressing and cosmetics, and healthcare) has been estimated. Methods The survey included 150 workers from four economic activities. The FINDRISK questionnaire was distributed among them. Plasma glucose and serum lipids (HDL, LDL, triglycerides) were analyzed. The statistical analysis of the results was done using SPSS 16. Results The mean FINDRISK score for the age group up to 25 years is 3.6 ± 3.8, and for respondents above 55 years - 10.1 ± 5.0. The analysis highlights the higher risk of developing diabetes among healthcare workers, where the score of older workers is 11.63 ± 6.61, as well as in the textile and clothing industry (11.17 ± 4.3). These results call attention to a potential link between the occupation and the risk of developing type 2 diabetes in these sectors of the economy and the need for additional measures to search for causes and prevention. Conclusions A significant proportion of the participants over 55 years old in the healthcare and textile and clothing sectors are at an increased risk of developing type 2 diabetes, which requires a change in lifestyle, as well as the identification of workplace hazards that lead to these results. The FINDRISK questionnaire can serve as an indirect assessment of the cardiovascular risk of older workers. Additional preventive measures are needed to limit the risk of developing type 2 diabetes mellitus as well as cardiovascular risk in the identified risky occupations. Key messages Occupation could contribute to the life style risk factors for developing diabetes type 2. Occupational risk reduction measures and health promotion are needed to protects workers.

scholarly journals СУЧАСНІ ПІДХОДИ ДО ФАРМАКОЛОГІЧНОЇ КОРЕКЦІЇ МЕТАБОЛІЧНИХ ЗРУШЕНЬ ПРИ ЦУКРОВОМУ ДІАБЕТІ ТИПУ 2

2019 ◽  
Vol 77 (3) ◽  
pp. 71-80
Author(s):  
Kh. I. Kurylo ◽  
A. S. Volska ◽  
I. M. Klishch ◽  
B. V. Zablotskyi
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Type 2 Diabetes ◽  
Metabolic Syndrome ◽  
Type 2 Diabetes Mellitus ◽  
Diabetes Type 2 ◽  
Diabetes Type ◽  
Metabolic Changes ◽  
Hypoglycemic Action

Diabetes mellitus is caused by one of the largest medical and social problems in Ukraine, because it causes a high risk of invasive disease. According to the WHO data, the number of patients is rising and people of varying age groups become ill, which causes an increase in the incidence of 3 to 4 pauses and the overall life expectancy of 20-30%. Pathogenesis of diabetes mellitus and enclosure, require the extraction of drugs for prophylaxis and treatment with late pharmacological effects. One of these is a herbal remedy. Analysis and systematization of the literature on metabolitotropic effects and substantiation of the use of new goat's-rue, blueberry and taurine phytocompositions for the correction of metabolic changes in diabetes type 2 were carried out. The methods of information search, analysis of literature on the medicinal plants with hypoglycemic action were used. The literary resources on pharmacological correction of metabolic changes in diabetes type 2 deal with natural herbs and amino acids that possess hypoglycemic action and can be used with therapeutic and prophylactic measure in patients with type 2 diabetes. In type 2 diabetes mellitus significant anticytolytic, detoxifying and antioxidant properties of phytocompositions were confirmed. It is known that in hyperglycemia and insulin resistance that occur at type 2 diabetes mellitus end products of glycosylation and glucose autooxidation are formed, which is accompanied by the activation of lipid peroxidation and the formation of a large number of free radicals. It is known that one of the basic mechanisms for the development of insulin resistance, diabetes mellitus and specific diabetic angiopathies is oxidative stress. One of the major pathogenetic factors in the development and course of type 2 diabetes mellitus is metabolic syndrome. It has been established that correction using both investigated phytocompositions and reference phytopreparation with different efficiency prevented the development of metabolic changes in metabolic syndrome. Biologically active components of medicinal plants, may show hypoglycemic effect which will influence the activity of the enzymes, glucose transcription and the function of the peptide to the incyline, the processes which play an important role in the pathogenesis of diabetes.

scholarly journals Can Chrono-Nutrition Help Prevent Diabetes?

2022 ◽  
Vol 5 (1) ◽  
pp. 01-02
Author(s):  
Akbar Nikkhah
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Diabetes Type 2 ◽  
Diabetes Type ◽  
Circadian Period ◽  
Insulin Metabolism ◽  
Fast Foods ◽  
Lack Of Exercise

This editorial aimed to put forward a question if chrono-nutrition can help prevent diabetes through optimizing circadian rhythms of glucose metabolism. With the advancing mechanization, eating behavior (timing, sequence, and frequency) has changed. People are now more willing to eat fast foods at suboptimal times of the circadian period. Growing evidence suggests that untimely eating and lack of exercise can interfere with optimal physiological rhythms of glucose and insulin metabolism that can lead to diabetes. Type 2 diabetes mellitus (T2D) is a foremost metabolic disorder worldwide occurring largely due to suboptimal eating timing and lifestyle. Consuming less sugars and carbohydrates during evening and overnight may help optimize human chrono-physiology. Chrono-nutrition via optimizing the timing of meals is a growing science that needs to be well practiced to help prevent or possibly reduce risks of T2D in today’s complicated life.

scholarly journals ELEMENTAL MARKERS IN PATIENTS WITH DIABETES TYPE 2 DIABETES MELLITUS LIVING IN THE NORTHERN REGION

2019 ◽  
Vol 20 (3) ◽  
pp. 54-61
Author(s):  
T.Yа. Korchina ◽  
◽  
V.I. Korchin ◽  
K.A. Cherepanova ◽  
A.B. Bogdanovich ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Diabetes Type 2 ◽  
Northern Region ◽  
Diabetes Type ◽  
Patients With Diabetes

Eksplorasi Kesadaran Diri, Persepsi Dan Sikap Pada Individu Yang Memiliki Riwayat Keluarga Diabetes Melitus Tipe 2

2019 ◽  
Vol 1 (1) ◽  
pp. 52-62
Author(s):  
Mulia Mayangsari
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Family History ◽  
Diabetes Type 2 ◽  
Diabetes Type ◽  
Self Awareness ◽  
Perceptions And Attitudes ◽  
History Of ◽  
Diabetes Melitus

 Individuals who have a family history oftype 2 diabetes mellitus (DM) have a highrisk for type 2 diabetes. Type 2 diabetescan be prevented by improving modifiablerisk factors, supported by self-awareness,perceptions and attitudes of individualswho have a high family history of DM. Thisstudy used a qualitative phenomenologicaldesign. A Purposive Sampling techiniquewas applied to determine individuals whohad parents with type 2 diabetes. Nineindividuals participated in this study. AQualitative content analysis with Collaiziapproach used as a data analysis method.The main themes depicted individuals selfawareness,perceptions, & attitudes were:denials that diabetes caused by heredityfactors; misperception about diabetes;“traditional modalities” as a preventionmeasurement toward type 2 diabetes; andDM is perceived as a “threatening disease”.Further study is needed to examine indepth the themes that have been identifiedon the number of participants are morenumerous and varied.

TYPE 2 DIABETES MELLITUS REMISSION AND ITS PREDICTION AFTER TWO-STAGE SURGICAL TREATMENT OF PATIENTS WITH MORBID OBESITY

2019 ◽  
Vol 72 (5) ◽  
pp. 739-743
Author(s):  
Oleksandr Yu. Ioffe ◽  
Mykola S. Kryvopustov ◽  
Yuri A. Dibrova ◽  
Yuri P. Tsiura
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Morbid Obesity ◽  
Weight Loss ◽  
Type 2 Diabetes Mellitus ◽  
Surgical Treatment ◽  
Two Stage ◽  
C Peptide ◽  
Peptide Level

Introduction: Morbid obesity (MO) has a significant impact on mortality, health and quality of life of patients. Type 2 diabetes mellitus (T2DM) is a common comorbidity in patients with MO. The aim is to study T2DM remission and to develop a prediction model for T2DM remission after two-stage surgical treatment of patients with MO. Materials and methods: The study included 97 patients with MO. The mean BMI was 68.08 (95% CI: 66.45 - 69.71) kg/m2. 70 (72,2%) patients with MO were diagnosed with T2DM. The first stage of treatment for the main group (n=60) included the IGB placement, for the control group (n=37) - conservative therapy. In the second stage of treatment the patients underwent bariatric surgery. The study addresses such indicators as BMI, percentage of weight loss, percentage of excess weight loss, ASA physical status class, fasting glucose level, HbA1c, C-peptide. Results: Two-stage treatment of morbidly obese patients with T2DM promotes complete T2DM remission in 68.1% of patients. The risk prediction model for failure to achieve complete T2DM remission 12 months after LRYGB based on a baseline C-peptide level has a high predictive value, AUC = 0.84 (95% CI: 0.69-0.93), OR = 0.23 ( 95% CI: 0.08-0.67). Conclusions: Two-stage treatment of patients with MO promotes improvement of carbohydrate metabolism indicators. With a C-peptide level > 3.7 ng/ml, prediction of complete T2DM remission 12 months after Laparoscopic Roux-en-Y Gastric Bypass is favorable.

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