SESSILE SERRATED ADENOMA/POLYP DETECTION RATE OF WATER EXCHANGE, ENDOCUFF AND CAP COLONOSCOPY – A NETWORK META‐ANALYSIS

2021 ◽  
Author(s):  
Paul P. Shao ◽  
Changhan R. Shao ◽  
Tahmineh Romero ◽  
Felix W. Leung
Keyword(s):  
Detection Rate ◽  
Water Exchange ◽  
Meta Analysis ◽  
Polyp Detection ◽  
Sessile Serrated Adenoma ◽  
Serrated Adenoma ◽  
Polyp Detection Rate

scholarly journals Enhanced Patient Education for Colonic Polyp and Adenoma Detection: Meta-Analysis of Randomized Controlled Trials (Preprint)

2019 ◽  
Author(s):  
Xu Tian ◽  
Ling-Li Xu ◽  
Xiao-Ling Liu ◽  
Wei-Qing Chen
Keyword(s):  
Detection Rate ◽  
Meta Analysis ◽  
Adenoma Detection Rate ◽  
Advanced Adenoma ◽  
Polyp Detection ◽  
Sessile Serrated Adenoma ◽  
Serrated Adenoma ◽  
Polyp Detection Rate ◽  
Adenoma Detection ◽  
Number Of Patients

BACKGROUND To improve patients’ comprehension of bowel preparation instructions before colonoscopy, enhanced patient education (EPE) such as cartoon pictures or other visual aids, phone calls, mobile apps, multimedia education and social media apps have been proposed. However, it is uncertain whether EPE can increase the detection rate of colonic polyps and adenomas. OBJECTIVE This meta-analysis aimed to evaluate the efficacy of EPE in detecting colonic polyps and adenomas. METHODS We searched PubMed, EMBASE, and Cochrane Central Register of Controlled Trials from their inception to June 2019 for the identification of trials comparing the EPE with standard patient education for outpatients undergoing colonoscopy. We used a random effects model to calculate summary estimates of the polyp detection rate (defined as the number of patients with at least one polyp divided by the total number of patients undergoing selective colonoscopy), adenoma detection rate (defined as the number of patients with at least one adenoma divided by the total number of patients undergoing selective colonoscopy), advanced adenoma detection rate (defined as the number of patients with at least one advanced adenoma divided by the total number of patients undergoing selective colonoscopy), sessile serrated adenoma detection rate (defined as the number of patients with at least one sessile serrated adenoma divided by the total number of patients undergoing selective colonoscopy), cancer detection rate (defined as the number of patients with at least one cancer divided by the total number of patients undergoing selective colonoscopy), or adenoma detection rate - plus (defined as the number of additional adenomas found after the first adenoma per colonoscopy). Moreover, we conducted trial sequential analysis (TSA) to determine the robustness of summary estimates of all primary outcomes. RESULTS We included 10 randomized controlled trials enrolling 4560 participants for analysis. The meta-analysis suggested that EPE was associated with an increased polyp detection rate (9 trials; 3781 participants; risk ratio [RR] 1.19, 95% CI 1.05-1.35; <i>P</i>&lt;.05; I<sup>2</sup>=42%) and adenoma detection rate (5 trials; 2133 participants; RR 1.37, 95% CI 1.15-1.64; <i>P</i>&lt;.001; I2=0%), which were established by TSA. Pooled result from the inverse-variance model illustrated an increase in the sessile serrated adenoma detection rate (3 trials; 1248 participants; odds ratio 1.76, 95% CI 1.22-2.53; <i>P</i>&lt;.05; I<sup>2</sup>=0%). One trial suggested an increase in the adenoma detection rate - plus (RR 4.39, 95% CI 2.91-6.61; <i>P</i>&lt;.001). Pooled estimates from 3 (1649 participants) and 2 trials (1375 participants) generated no evidence of statistical difference for the advanced adenoma detection rate and cancer detection rate, respectively. CONCLUSIONS The current evidence indicates that EPE should be recommended to instruct bowel preparation in patients undergoing colonoscopy because it can increase the polyp detection rate, adenoma detection rate, and sessile serrated adenoma detection rate. However, further trials are warranted to determine the efficacy of EPE for advanced adenoma detection rate, adenoma detection rate - plus, and cancer detection rate because of limited data.

scholarly journals Enhanced Patient Education for Colonic Polyp and Adenoma Detection: Meta-Analysis of Randomized Controlled Trials

10.2196/17372 ◽  
2020 ◽  
Vol 8 (6) ◽  
pp. e17372
Author(s):  
Xu Tian ◽  
Ling-Li Xu ◽  
Xiao-Ling Liu ◽  
Wei-Qing Chen
Keyword(s):  
Detection Rate ◽  
Meta Analysis ◽  
Adenoma Detection Rate ◽  
Advanced Adenoma ◽  
Polyp Detection ◽  
Sessile Serrated Adenoma ◽  
Serrated Adenoma ◽  
Polyp Detection Rate ◽  
Adenoma Detection ◽  
Number Of Patients

Background To improve patients’ comprehension of bowel preparation instructions before colonoscopy, enhanced patient education (EPE) such as cartoon pictures or other visual aids, phone calls, mobile apps, multimedia education and social media apps have been proposed. However, it is uncertain whether EPE can increase the detection rate of colonic polyps and adenomas. Objective This meta-analysis aimed to evaluate the efficacy of EPE in detecting colonic polyps and adenomas. Methods We searched PubMed, EMBASE, and Cochrane Central Register of Controlled Trials from their inception to June 2019 for the identification of trials comparing the EPE with standard patient education for outpatients undergoing colonoscopy. We used a random effects model to calculate summary estimates of the polyp detection rate (defined as the number of patients with at least one polyp divided by the total number of patients undergoing selective colonoscopy), adenoma detection rate (defined as the number of patients with at least one adenoma divided by the total number of patients undergoing selective colonoscopy), advanced adenoma detection rate (defined as the number of patients with at least one advanced adenoma divided by the total number of patients undergoing selective colonoscopy), sessile serrated adenoma detection rate (defined as the number of patients with at least one sessile serrated adenoma divided by the total number of patients undergoing selective colonoscopy), cancer detection rate (defined as the number of patients with at least one cancer divided by the total number of patients undergoing selective colonoscopy), or adenoma detection rate - plus (defined as the number of additional adenomas found after the first adenoma per colonoscopy). Moreover, we conducted trial sequential analysis (TSA) to determine the robustness of summary estimates of all primary outcomes. Results We included 10 randomized controlled trials enrolling 4560 participants for analysis. The meta-analysis suggested that EPE was associated with an increased polyp detection rate (9 trials; 3781 participants; risk ratio [RR] 1.19, 95% CI 1.05-1.35; P<.05; I2=42%) and adenoma detection rate (5 trials; 2133 participants; RR 1.37, 95% CI 1.15-1.64; P<.001; I2=0%), which were established by TSA. Pooled result from the inverse-variance model illustrated an increase in the sessile serrated adenoma detection rate (3 trials; 1248 participants; odds ratio 1.76, 95% CI 1.22-2.53; P<.05; I2=0%). One trial suggested an increase in the adenoma detection rate - plus (RR 4.39, 95% CI 2.91-6.61; P<.001). Pooled estimates from 3 (1649 participants) and 2 trials (1375 participants) generated no evidence of statistical difference for the advanced adenoma detection rate and cancer detection rate, respectively. Conclusions The current evidence indicates that EPE should be recommended to instruct bowel preparation in patients undergoing colonoscopy because it can increase the polyp detection rate, adenoma detection rate, and sessile serrated adenoma detection rate. However, further trials are warranted to determine the efficacy of EPE for advanced adenoma detection rate, adenoma detection rate - plus, and cancer detection rate because of limited data.

scholarly journals Polyp Detection Rate as a Surrogate for Adenoma and Sessile Serrated Adenoma/Polyp Detection Rates

2020 ◽  
Vol 7 (3) ◽  
pp. 74-82 ◽  
Author(s):  
Leonardo Zorron Cheng Tao Pu ◽  
Gurfarmaan Singh ◽  
Khizar Rana ◽  
Masanao Nakamura ◽  
Takeshi Yamamura ◽  
...  
Keyword(s):  
Detection Rate ◽  
Polyp Detection ◽  
Sessile Serrated Adenoma ◽  
Serrated Adenoma ◽  
Detection Rates ◽  
Polyp Detection Rate

Impact of Split Dose Bowel Preparation on Sessile Serrated Adenoma/Polyp Detection Rate

2017 ◽  
Vol 112 ◽  
pp. S127-S128
Author(s):  
Suhag Patel ◽  
Wissam Kiwan ◽  
Hala Nas ◽  
Sachin Goyal ◽  
Stephanie Judd ◽  
...  
Keyword(s):  
Bowel Preparation ◽  
Detection Rate ◽  
Polyp Detection ◽  
Sessile Serrated Adenoma ◽  
Serrated Adenoma ◽  
Split Dose ◽  
Polyp Detection Rate

scholarly journals Cap-assisted endoscopy: Do we have enough evidence?

2018 ◽  
Vol 06 (10) ◽  
pp. E1224-E1226 ◽  
Author(s):  
Thomas Frieling
Keyword(s):  
Clinical Practice ◽  
Detection Rate ◽  
Meta Analysis ◽  
Intubation Time ◽  
Polyp Detection ◽  
Cecal Intubation ◽  
Polyp Detection Rate ◽  
Adenoma Detection ◽  
Clinical Benefits ◽  
Transparent Cap

AbstractSo, is there enough evidence to incorporate CC in clinical practice? If we interpret the literature and the meta-analysis by Nutalapati et al., the answer for the clinically-focused endoscopist, with regard to adenoma detection rate (ADR), at present, may be “no”. Significant differences do not necessarily imply clinical benefits and translation into clinical practice. The answer for the improvement of cecal intubation frequency and intubation time by the cap depends on the focus of training commitment, because these effects of the cap may be beneficial, especially for unexperienced endoscopists. It is obvious that further studies are needed. In this line, it is interesting to know, that in a recent meta-analysis of prospective studies, the length of the transparent cap had opposite effects on investigation time and polyp detection rate. Whereas, the anal to cecal time was significantly shortened by a cap length of > 7 mm and a polyp detection rate was significantly improved by a cap length of < 4 mm.

Su1609 Improved Overall Adenoma Detection Rate and Sessile Serrated Adenoma Detection Rate With Endocuff: A Systematic Review and Meta-Analysis

2017 ◽  
Vol 85 (5) ◽  
pp. AB362
Author(s):  
Madhav Desai ◽  
Venkat Nutalapati ◽  
Shreyas Saligram ◽  
Chaitanya Pant ◽  
Vijay Kanakadandi ◽  
...  
Keyword(s):  
Systematic Review ◽  
Detection Rate ◽  
Meta Analysis ◽  
Adenoma Detection Rate ◽  
Sessile Serrated Adenoma ◽  
Serrated Adenoma ◽  
Adenoma Detection
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