scholarly journals Gastrointestinal: Esophageal adenocarcinoma arising from circumferential ectopic gastric mucosa: A case report

Author(s):  
D Ohki ◽  
Y Tsuji ◽  
S Yamazawa ◽  
T Ushiku ◽  
K Tateishi
2017 ◽  
Vol 26 (2) ◽  
pp. 193-197 ◽  
Author(s):  
Ryosuke Gushima ◽  
Rei Narita ◽  
Takashi Shono ◽  
Hideaki Naoe ◽  
Takashi Yao ◽  
...  

Background: Adenocarcinoma with enteroblastic differentiation is a subtype of alpha-fetoprotein (AFP) producing adenocarcinoma. This type of tumor is associated with a poor prognosis and is prone to metastasize. Esophageal adenocarcinoma with enteroblastic differentiation is extremely rare.Case presentation: The patient was a 65-year-old woman who was referred to our hospital with dysphagia. Endoscopic examination revealed an elevated lesion 20mm in diameter at 17cm from the upper incisors. Endoscopic submucosa dissection (ESD) was performed and histopathological examination revealed tubular adenocarcinoma composed of cuboidal cells with clear cell cytoplasm. Immunohistochemical stain was diffusely positive for Sall-like protein 4 (SALL4) and weakly positive for AFP and glypican 3. From this result, we diagnosed esophageal adenocarcinoma with enteroblastic differentiation. The patient is still alive without recurrence of cancer 40 months after ESD.Conclusion: To our knowledge, this is the first report to undergo ESD for esophageal adenocarcinoma with enteroblastic differentiation arising from ectopic gastric mucosa in the esophagus.Abbreviations: AFP: alfa-fetoprotein; CA19-9: carbohydrate antigen 19-9; CEA: carcinoembryonic antigen; ESD: endoscopic submucosal dissection; EUS: endoscopic ultrasound; FDG-PET: [18F] fluorodeoxyglucose positron emission tomography; ME: magnifying endoscopy; NBI: narrow band imaging; SALL 4: Sall-like protein 4; SCC: squamous cell carcinoma antigen.


2015 ◽  
Vol 76 (9) ◽  
pp. 2231-2236 ◽  
Author(s):  
Yuichiro OKUMURA ◽  
Susumu MIYAZAKI ◽  
Kazumasa FUJITANI ◽  
Hiroaki FUSHIMI ◽  
Katsuki DANNO ◽  
...  

1974 ◽  
Vol 60 (1) ◽  
pp. 17-24 ◽  
Author(s):  
Claudio Clemente

A case of adenocarcinoma of the upper third of the esophagus, arising from ectopic mucosa of gastric type, is described. The possible origins, from ectopic islets of gastric mucosa, tracheobronchial rests or esophageal glands, are discussed. The precence of ectopic gastric mucosa on the surface of the esophagus adjacent to the tumor suggests that this esophageal adenocarcinoma arose from ectopic gastric mucosa.


2005 ◽  
Vol 61 (2) ◽  
pp. 335-338 ◽  
Author(s):  
Junya Oguma ◽  
Soji Ozawa ◽  
Tai Omori ◽  
Yuko Kitagawa ◽  
Yoshiro Saikawa ◽  
...  

2006 ◽  
Vol 41 (8) ◽  
pp. e7-e9 ◽  
Author(s):  
Paul Daher ◽  
Edward Riachy ◽  
Smart Zeidan ◽  
Alain Saad

2013 ◽  
Vol 8 (1) ◽  
Author(s):  
Zhefeng Zhang ◽  
Feng Jin ◽  
Hao Wu ◽  
Shulian Tan ◽  
Zhuang Tian ◽  
...  

2003 ◽  
Vol 57 (2) ◽  
pp. 263-266 ◽  
Author(s):  
Nobuo Hirayama ◽  
Miwako Arima ◽  
Shin-ichi Miyazaki ◽  
Hideaki Shimada ◽  
Shin-ichi Okazumi ◽  
...  

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