Macro‐encapsulation of mesenchymal stem cells in acute and chronic liver injury animal models

2021 ◽  
Author(s):  
Hyeon Tae Kang ◽  
Kiseok Jang ◽  
Dae Won Jun ◽  
Eileen L Yoon ◽  
Seung Min Lee ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Animal Models ◽  
Liver Injury ◽  
Chronic Liver ◽  
Chronic Liver Injury

scholarly journals Icariin-treated human umbilical cord mesenchymal stem cells decrease chronic liver injury in mice

2016 ◽  
Vol 69 (1) ◽  
pp. 19-29 ◽  
Author(s):  
Huantian Cui ◽  
Zhen Liu ◽  
Li Wang ◽  
Yuhong Bian ◽  
Wen Li ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Liver Injury ◽  
Umbilical Cord ◽  
Chronic Liver ◽  
Human Umbilical Cord ◽  
Chronic Liver Injury

scholarly journals Mesenchymal Stem Cells Transplantation following Partial Hepatectomy: A New Concept to Promote Liver Regeneration—Systematic Review of the Literature Focused on Experimental Studies in Rodent Models

2017 ◽  
Vol 2017 ◽  
pp. 1-22 ◽  
Author(s):  
Ioannis G. Papanikolaou ◽  
Charalambos Katselis ◽  
Konstantinos Apostolou ◽  
Themistoklis Feretis ◽  
Maria Lymperi ◽  
...  
Keyword(s):  
Systematic Review ◽  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Liver Failure ◽  
Liver Regeneration ◽  
Partial Hepatectomy ◽  
Chronic Liver ◽  
Review Of The Literature ◽  
Chronic Liver Injury ◽  
Stem Cells Transplantation

Mesenchymal stem cells (MSCs) are an attractive source for regenerative medicine because they are easily accessible through minimally invasive methods and have the potential to enhance liver regeneration (LG) and improve liver function, following partial hepatectomy (PH) and acute or chronic liver injury. A systematic review of the literature was conducted for articles published up to September 1st, 2016, using the MEDLINE database. The keywords that were used in various combinations were as follows: “Mesenchymal stem cells”, “transplantation”, “stem cells”, “adipose tissue derived stem cells”, “bone marrow-derived stem cells”, “partial hepatectomy”, “acute liver failure”, “chronic liver failure”, “liver fibrosis”, “liver cirrhosis”, “rats”, “mice”, and “liver regeneration”. All introduced keywords were searched for separately in MeSH Database to control relevance and terminological accuracy and validity. A total of 41 articles were identified for potential inclusion and reviewed in detail. After a strict selection process, a total of 28 articles were excluded, leaving 13 articles to form the basis of this systematic review. MSCs transplantation promoted LG and improved liver function. Furthermore, MSCs had the ability to differentiate in hepatocyte-like cells, increase survival, and protect hepatocytes by paracrine mechanisms. MSCs transplantation may provide beneficial effects in the process of LG after PH and acute or chronic liver injury. They may represent a new therapeutic option to treat posthepatectomy acute liver failure.

Cell Therapy Using Adipose-derived Stem Cells for Chronic Liver Injury in Mice

Cell Medicine ◽  
2012 ◽  
Author(s):  
Kazuo Ohashi ◽  
Yoshinori Matsubara ◽  
Kohei Tatsumi ◽  
Ayako Kohori ◽  
Rie Utoh ◽  
...  
Keyword(s):  
Stem Cells ◽  
Liver Injury ◽  
Cell Therapy ◽  
Chronic Liver ◽  
Adipose Derived Stem Cells ◽  
Chronic Liver Injury

scholarly journals Cell Therapy Using Adipose-Derived Stem Cells for Chronic Liver Injury in Mice

Cell Medicine ◽  
2012 ◽  
Vol 3 (1-3) ◽  
pp. 113-119 ◽  
Author(s):  
Kazuo Ohashi ◽  
Yoshinori Matsubara ◽  
Kohei Tatsumi ◽  
Ayako Kohori ◽  
Rie Utoh ◽  
...  
Keyword(s):  
Stem Cells ◽  
Liver Injury ◽  
Cell Therapy ◽  
Chronic Liver ◽  
Adipose Derived Stem Cells ◽  
Chronic Liver Injury

scholarly journals Oct4 and Hnf4α-induced hepatic stem cells ameliorate chronic liver injury in liver fibrosis model

PLoS ONE ◽  
2019 ◽  
Vol 14 (8) ◽  
pp. e0221085 ◽  
Author(s):  
Myung Rae Park ◽  
Man Sze Wong ◽  
Marcos J. Araúzo-Bravo ◽  
Hyunah Lee ◽  
Donggyu Nam ◽  
...  
Keyword(s):  
Stem Cells ◽  
Liver Fibrosis ◽  
Liver Injury ◽  
Chronic Liver ◽  
Hepatic Stem Cells ◽  
Chronic Liver Injury
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