Tumor location and patient sex are novel risk factors of lymph node metastasis in T1 colorectal cancer

2020 ◽  
Vol 35 (12) ◽  
pp. 2292-2292
Author(s):  
H Miyachi ◽  
S Kudo ◽  
K Mochizuki ◽  
Y Kouyama ◽  
K Ichimasa
Keyword(s):  
Colorectal Cancer ◽  
Risk Factors ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Tumor Location ◽  
Node Metastasis ◽  
T1 Colorectal Cancer ◽  
Novel Risk Factors

Novel risk factors for lymph node metastasis in early invasive colorectal cancer: a multi-institution pathology review

2013 ◽  
Vol 49 (9) ◽  
pp. 1314-1323 ◽  
Author(s):  
Hideki Ueno ◽  
Kazuo Hase ◽  
Yojiro Hashiguchi ◽  
Hideyuki Shimazaki ◽  
Shinji Yoshii ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Risk Factors ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Node Metastasis ◽  
Novel Risk Factors ◽  
Pathology Review

scholarly journals Histopathologic risk factors for lymph node metastasis in patients with T1 colorectal cancer

2017 ◽  
Vol 93 (5) ◽  
pp. 266 ◽  
Author(s):  
Ryun Kyong Ha ◽  
Kyung Su Han ◽  
Dae Kyung Sohn ◽  
Byung Chang Kim ◽  
Chang Won Hong ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Risk Factors ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Node Metastasis ◽  
T1 Colorectal Cancer

Classic and Novel Histopathological Risk Factors for Lymph Node Metastasis in T1 Colorectal Cancer

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Mark A. Dykstra ◽  
Tamara I. Gimon ◽  
Paul E. Ronksley ◽  
W. Donald Buie ◽  
Anthony R. MacLean
Keyword(s):  
Colorectal Cancer ◽  
Risk Factors ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Node Metastasis ◽  
T1 Colorectal Cancer

Impact of tumor location on lymph node metastasis in T1 colorectal cancer

2016 ◽  
Vol 401 (5) ◽  
pp. 627-632 ◽  
Author(s):  
Erman Aytac ◽  
Emre Gorgun ◽  
Meagan M Costedio ◽  
Luca Stocchi ◽  
Feza H Remzi ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Tumor Location ◽  
Node Metastasis ◽  
T1 Colorectal Cancer

Tumor Budding and Pathological Differentiation Are Predictive Markers for Lymph Node Metastasis in T1 Colorectal Cancer

2006 ◽  
Vol 63 (5) ◽  
pp. AB216 ◽  
Author(s):  
Hitoshi Yamauchi ◽  
Kazutomo Togashi ◽  
Hiroshi Kawamura ◽  
Junichi Sasaki ◽  
Masaki Okada ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Predictive Markers ◽  
Tumor Budding ◽  
Node Metastasis ◽  
Pathological Differentiation ◽  
T1 Colorectal Cancer

scholarly journals Tumour–stroma ratio has poor prognostic value in non-pedunculated T1 colorectal cancer: A multi-centre case-cohort study

2020 ◽  
pp. 205064062097532
Author(s):  
Hao Dang ◽  
Gabi W van Pelt ◽  
Krijn JC Haasnoot ◽  
Yara Backes ◽  
Sjoerd G Elias ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Prognostic Value ◽  
Adverse Outcome ◽  
Advanced Stage ◽  
Tumour Stroma ◽  
Node Metastasis ◽  
Increased Risk ◽  
T1 Colorectal Cancer

Background Current risk stratification models for early invasive (T1) colorectal cancer are not able to discriminate accurately between prognostic favourable and unfavourable tumours, resulting in over-treatment of a large (>80%) proportion of T1 colorectal cancer patients. The tumour–stroma ratio (TSR), which is a measure for the relative amount of desmoplastic tumour stroma, is reported to be a strong independent prognostic factor in advanced-stage colorectal cancer, with a high stromal content being associated with worse prognosis and survival. We aimed to investigate whether the TSR predicts clinical outcome in patients with non-pedunculated T1 colorectal cancer. Methods Hematoxylin and eosin (H&E)-stained tumour tissue slides from a retrospective multi-centre case cohort of patients with non-pedunculated surgically treated T1 colorectal cancer were assessed for TSR by two independent observers who were blinded for clinical outcomes. The primary end point was adverse outcome, which was defined as the presence of lymph node metastasis in the resection specimen or colorectal cancer recurrence during follow-up. Results All 261 patients in the case cohort had H&E slides available for TSR scoring. Of these, 183 were scored as stroma-low, and 78 were scored as stroma-high. There was moderate inter-observer agreement (κ = 0.42). In total, 41 patients had lymph node metastasis, 17 patients had recurrent cancer and five had both. Stroma-high tumours were not associated with an increased risk for an adverse outcome (adjusted hazard ratio = 0.66, 95% confidence interval 0.37–1.18; p = 0.163). Conclusions Our study emphasises that existing prognosticators may not be simply extrapolated to T1 colorectal cancers, even though their prognostic value has been widely validated in more advanced-stage tumours.

Risk Factors for Lymph Node Metastasis in Submucosal Invasive Colorectal Cancer

2008 ◽  
Vol 32 (9) ◽  
pp. 2089-2094 ◽  
Author(s):  
Pyong W. Choi ◽  
Chang Sik Yu ◽  
Se J. Jang ◽  
Sang H. Jung ◽  
Hee C. Kim ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Risk Factors ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Node Metastasis
Sign in / Sign up

Export Citation Format

Share Document