scholarly journals Patient‐reported outcomes in patients with non‐alcoholic fatty liver disease: A narrative review of Chronic Liver Disease Questionnaire‐non‐alcoholic fatty liver disease/non‐alcoholic steatohepatitis

2020 ◽  
Author(s):  
Sakura Yamamura ◽  
Dan Nakano ◽  
Ryuki Hashida ◽  
Tsubasa Tsutsumi ◽  
Takumi Kawaguchi ◽  
...  
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Chronic Liver Disease ◽  
Fatty Liver Disease ◽  
Patient Reported Outcomes ◽  
Alcoholic Fatty Liver ◽  
Patient Reported ◽  
Chronic Liver Disease Questionnaire ◽  
Alcoholic Fatty Liver Disease ◽  
Disease Questionnaire

scholarly journals Comparative analysis of indices of the metabolic syndrome in patients with and without non-alcoholic fatty liver disease at a teaching hospital in Nnewi, South-East, Nigeria

2019 ◽  
Vol 10 (2) ◽  
pp. 40-45
Author(s):  
Nneka S. Chukwurah ◽  
Uchenna C. Okonkwo ◽  
Anele E. Ihekwaba
Keyword(s):  
Metabolic Syndrome ◽  
Liver Disease ◽  
Fatty Liver ◽  
Chronic Liver Disease ◽  
Fatty Liver Disease ◽  
Chronic Liver ◽  
Health Concern ◽  
Alcoholic Fatty Liver ◽  
The Metabolic Syndrome ◽  
Alcoholic Fatty Liver Disease

Background: Non-Alcoholic fatty liver disease (NAFLD) has become a worldwide health concern with increase in the global incidence of obesity and it is now considered the hepatic component of the metabolic syndrome. Aims and Objective: The study’s aim was to compare the indices of the metabolic syndrome in compensated chronic liver disease patients with and without NAFLD at NAUTH, Nnewi. Materials and Methods: A total of 136 consecutive patients with compensated chronic liver disease were recruited into the study. A structured questionnaire was administered to obtain relevant socio-demographic data. NAFLD was diagnosed based on clinical, biochemical, ultrasonographic and in a few histological features. The Adult Treatment Panel III criteria were used to identify patients with the metabolic syndrome. Results: Of the 136 participants recruited into the study, 52 (38.2%) fulfilled 2 or more diagnostic criteria for NAFLD with a male: female ratio of 1:1.36. The mean (SD) age of persons with NAFLD was 45.12 (±8.07) years compared to 47.49(±11.79) years for persons without NAFLD. The difference was not statistically significant (p=0.2). Body mass index (BMI), central obesity (waist circumference), fasting blood sugar, blood pressure, total cholesterol and triglycerides were significantly higher in the NAFLD group (p= <0.05) respectively. Conclusion: Indices of the metabolic syndrome were more prevalent in persons with NAFLD. It is recommended that patients with NAFLD be screened for metabolic syndrome and appropriate therapy instituted to decrease the risk of both hepatic and cardiovascular complications.

scholarly journals Nonalcoholic Fatty Liver Disease and Metabolic Syndrome among patients attending in a tertiary care center in Bangladesh

2018 ◽  
Vol 28 (2) ◽  
pp. 44-51
Author(s):  
MMR Khan ◽  
MK Rahman ◽  
NK Sana ◽  
PM Basak ◽  
BC Sarker ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Liver Disease ◽  
Fatty Liver ◽  
Chronic Liver Disease ◽  
Fatty Liver Disease ◽  
Care Center ◽  
Tertiary Care ◽  
Tertiary Care Center ◽  
Alcoholic Fatty Liver ◽  
Alcoholic Fatty Liver Disease

Non-alcoholic fatty liver disease (NAFLD) is an emerging chronic liver disease and may lead to liver cirrhosis and hepatocellular carcinoma. It is now the most common chronic liver disease in many developed as well as developing countries. This hospital based study was done to see the prevalence of non-alcoholic fatty liver disease (NAFLD) and metabolic syndrome among patients attending in a tertiary care center in Bangladesh. Here, 334 nonalcoholic subjects of both sex and age were included. Metabolic syndrome was assessed by modified ATP III criteria and fatty liver diagnosis was based on ultrasound findings. 27.2% had the metabolic syndrome and was more common in female. Prevalence of NAFLD was 44% and was more common in female. Metabolic syndrome was found in 61.5% with NAFLD.TAJ 2015; 28(2): 44-51

Non-alcoholic steatohepatitis or autoimmune hepatitis? Sometimes a closer look under the surface is needed

2020 ◽  
Vol 13 (12) ◽  
pp. e238400
Author(s):  
Georgios N Dalekos ◽  
Nikolaos K Gatselis ◽  
George K Koukoulis
Keyword(s):  
Liver Disease ◽  
Fatty Liver ◽  
Autoimmune Hepatitis ◽  
Chronic Liver Disease ◽  
Rare Disease ◽  
Fatty Liver Disease ◽  
Alcoholic Fatty Liver ◽  
Female Predominance ◽  
Circulating Autoantibodies ◽  
Alcoholic Fatty Liver Disease

Non-alcoholic fatty liver disease (NAFLD) is nowadays the most common liver disease worldwide. Autoimmune hepatitis (AIH) is a relatively rare disease of the liver characterised by female predominance, circulating autoantibodies, polyclonal hypergammaglobulinaemia, interface hepatitis on histology and favourable response to immunosuppression. The possibility of an additional AIH diagnosis in patients with NAFLD (NAFLD/AIH concurrence) or the presence of AIH alone instead of a supposed NAFLD diagnosis represents a challenge for clinicians. We report herein two adult patients (a 33-year-old woman and a 59-year-old man) with a previous NAFLD diagnosis who proved finally to suffer from AIH alone. These two representative cases indicate how difficult and complicated could be sometimes the diagnosis of patients with AIH highlighting the range of disease manifestations and severity while they also underline that although NAFLD is by far the most frequent chronic liver disease this could not be always the case.

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