scholarly journals Short‐term and long‐term impacts of Helicobacter pylori eradication with reverse hybrid therapy on the gut microbiota

2019 ◽  
Vol 34 (11) ◽  
pp. 1968-1976 ◽  
Author(s):  
Ping‐I Hsu ◽  
Chao‐Yu Pan ◽  
John Y Kao ◽  
Feng‐Woei Tsay ◽  
Nan‐Jing Peng ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Gut Microbiota ◽  
Short Term ◽  
Hybrid Therapy ◽  
Helicobacter Pylori Eradication

scholarly journals Gut microbiome diversity is an independent predictor of survival in cervical cancer patients receiving chemoradiation

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Travis T. Sims ◽  
Molly B. El Alam ◽  
Tatiana V. Karpinets ◽  
Stephanie Dorta-Estremera ◽  
Venkatesh L. Hegde ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Radiation Therapy ◽  
Gut Microbiota ◽  
Cancer Patients ◽  
Gut Microbiome ◽  
Compositional Variation ◽  
Short Term ◽  
Microbiome Diversity ◽  
Term Survivor

AbstractDiversity of the gut microbiome is associated with higher response rates for cancer patients receiving immunotherapy but has not been investigated in patients receiving radiation therapy. Additionally, current studies investigating the gut microbiome and outcomes in cancer patients may not have adjusted for established risk factors. Here, we sought to determine if diversity and composition of the gut microbiome was independently associated with survival in cervical cancer patients receiving chemoradiation. Our study demonstrates that the diversity of gut microbiota is associated with a favorable response to chemoradiation. Additionally, compositional variation among patients correlated with short term and long-term survival. Short term survivor fecal samples were significantly enriched in Porphyromonas, Porphyromonadaceae, and Dialister, whereas long term survivor samples were significantly enriched in Escherichia Shigella, Enterobacteriaceae, and Enterobacteriales. Moreover, analysis of immune cells from cervical tumor brush samples by flow cytometry revealed that patients with a high microbiome diversity had increased tumor infiltration of CD4+ lymphocytes as well as activated subsets of CD4 cells expressing ki67+ and CD69+ over the course of radiation therapy. Modulation of the gut microbiota before chemoradiation might provide an alternative way to enhance treatment efficacy and improve treatment outcomes in cervical cancer patients.

Change of the grades of atrophy and intestinal metaplasia after helicobacter pylori eradication: long-term follow-up

2000 ◽  
Vol 118 (4) ◽  
pp. A1302-A1303
Author(s):  
Kiichi Satoh ◽  
Ken Kihira ◽  
Hiroshi Kawata ◽  
Keiko Fukazawa ◽  
Satoshi Kawakami ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Intestinal Metaplasia ◽  
Helicobacter Pylori Eradication ◽  
Long Term Follow Up

scholarly journals The Efficacy of Moxifloxacin-containing Triple Therapy after Hybrid Therapy Failure in Helicobacter pylori Eradication

2017 ◽  
Vol 70 (2) ◽  
pp. 72 ◽  
Author(s):  
Soohoon Kwon ◽  
Dong Ho Lee ◽  
Jae Bin Kang ◽  
Nayoung Kim ◽  
Young Soo Park ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Triple Therapy ◽  
Therapy Failure ◽  
Hybrid Therapy ◽  
Helicobacter Pylori Eradication

Long-term follow-up of gastric histology after Helicobacter pylori eradication

1996 ◽  
Vol 11 (7) ◽  
pp. 670-673 ◽  
Author(s):  
GEOFFREY M FORBES ◽  
J ROBIN WARREN ◽  
MARK E GLASER ◽  
DIGBY JE CULLEN ◽  
BARRY J MARSHALL ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Helicobacter Pylori Eradication ◽  
Long Term Follow Up
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