scholarly journals A review of lifestyle, metabolic risk factors, and blood‐based biomarkers for early diagnosis of pancreatic ductal adenocarcinoma

2019 ◽  
Vol 34 (2) ◽  
pp. 330-345 ◽  
Author(s):  
Yuanjie Pang ◽  
Michael V Holmes ◽  
Zhengming Chen ◽  
Christiana Kartsonaki
Keyword(s):  
Risk Factors ◽  
Early Diagnosis ◽  
Pancreatic Ductal Adenocarcinoma ◽  
Metabolic Risk Factors ◽  
Ductal Adenocarcinoma ◽  
Metabolic Risk

Correlation of Metabolic Risk Factors with Sessile Serrated Lesions

2020 ◽  
Vol 29 (2) ◽  
pp. 175-179
Author(s):  
Melania Macarie ◽  
Simona Bataga ◽  
Simona Mocan ◽  
Monica Pantea ◽  
Razvan Opaschi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Statistical Significance ◽  
Interval Cancer ◽  
Metabolic Risk Factors ◽  
Control Group ◽  
Anatomical Site ◽  
Metabolic Risk ◽  
Right Colon ◽  
Serrated Lesions ◽  
The Right

Background and Aims: The importance of sessile serrated lesions (SSLs) in the pathogenesis of colorectal carcinoma has been recently established. These are supposed to cause the so-called “interval cancer”, having a rapidly progressive growth and being difficult to detect and to obtain an endoscopic complete resection. We aimed to establish the most important metabolic risk factors for sessile serrated lesions. Methods: We performed a retrospective case-control study, on a series of 2918 consecutive patients who underwent colonoscopy in Gastroenterology and Endoscopy Unit, County Clinical Emergency Hospital, Târgu-Mureș, Romania between 1 st of January 2015-31 th of December 2017. In order to evaluate the metabolic risk factors for polyps’ development, enrolled participants were stratified in two groups, a study group, 33 patients with SSLs lesions, and a control group, 138 patients with adenomatous polyps, selected by systematic sampling for age and anatomical site. Independent variables investigated were: gender, smoking, alcohol consumption, obesity, arterial hypertension, diabetes, hypercholesterolemia, hypertriglyceridemia, hyperuricemia, nonalcoholic liver disease. Results: For SSLs the most common encountered localization was the right colon in 30.55% of cases. By comparative bivariate analysis between SSLs group and control group, it was observed that hypertension (p=0.03, OR 2.33, 95 %CI 1.03-5.24), obesity (p=0.03, OR 2.61, 95 %CI 1.08-6.30), hyperuricemia (p=0.04, OR 2.72, 95 %CI 1.28-7.55), high cholesterol (p=0.002, OR 3.42; 95 %CI 1.48-7.87), and high triglycerides level (p=0.0006, OR 5.75; 95 %CI 1.92-17.2) were statistically associated with SSLs development. By multivariate analysis hypertension and hypertriglyceridemia retained statistical significance. Conclusions: Our study showed that the highest prevalence of SSLs was in the right colon and hypertension and increased triglycerides levels were associated with the risk of SSLs development. These risk factors are easy to detect in clinical practice and may help identifying groups with high risk for colorectal cancer, where screening is recommended.

Effect of Pilates Exercise on Cardio Metabolic Risk Factors in Women with Type 2 Diabetes

2019 ◽  
Vol 87 (March) ◽  
pp. 851-851
Author(s):  
YASMIN M. ABD EL-MONIM, M.Sc. NESREEN G. EL-NAHAS, Ph.D. ◽  
SALLY A. HAKEM, M.D.
Keyword(s):  
Risk Factors ◽  
Type 2 Diabetes ◽  
Metabolic Risk Factors ◽  
Metabolic Risk

Relationships of Birthweight and Postnatal Growth with Metabolic Risk Factors in Junior School Children in Korea

2011 ◽  
Vol 7 (3) ◽  
pp. 153-159
Author(s):  
Kyoung Ae Kong ◽  
Hye Ah Lee ◽  
Bo Hyun Park ◽  
Jeong Wan Seo ◽  
Jee Young Oh ◽  
...  
Keyword(s):  
Risk Factors ◽  
School Children ◽  
Postnatal Growth ◽  
Metabolic Risk Factors ◽  
Metabolic Risk
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