Gastrointestinal: Unusual cause of acute cholangitis in a chronic pancreatitis patient

2018 ◽  
Vol 33 (6) ◽  
pp. 1164-1164
Author(s):  
JW Choe ◽  
JJ Lee ◽  
JJ Hyun
Keyword(s):  
Chronic Pancreatitis ◽  
Acute Cholangitis ◽  
Chronic Pancreatitis Patient

scholarly journals A Trial Study of Kikyo-to on Abdominal Symptoms in Chronic Pancreatitis Patient.

1997 ◽  
Vol 48 (1) ◽  
pp. 31-36
Author(s):  
Ichiro ARAI ◽  
Yasuhiro KOMATSU ◽  
Hisashi YAMAURA ◽  
Susumu TAGUCHI
Keyword(s):  
Chronic Pancreatitis ◽  
Chronic Pancreatitis Patient ◽  
Abdominal Symptoms

Severe Malabsorption Refractory to Pancreatic Enzyme Supplementation Unmasking Autoimmune Enteropathy in a Chronic Pancreatitis Patient

Pancreas ◽  
2016 ◽  
Vol 45 (8) ◽  
pp. e43-e44
Author(s):  
Julio Maria Fonseca Chebli ◽  
Liliana Andrade Chebli ◽  
Pedro Duarte Gaburri ◽  
Áureo Augusto de Almeida Delgado ◽  
Thais Mansur Ghetti Costa
Keyword(s):  
Chronic Pancreatitis ◽  
Pancreatic Enzyme ◽  
Chronic Pancreatitis Patient ◽  
Autoimmune Enteropathy ◽  
Enzyme Supplementation

scholarly journals Hydrogen Treatment Protects Mice Against Chronic Pancreatitis by Restoring Regulatory T Cells Loss

2017 ◽  
Vol 44 (5) ◽  
pp. 2005-2016 ◽  
Author(s):  
Luguang Chen ◽  
Chao Ma ◽  
Yun Bian ◽  
Jing Li ◽  
Tiegong Wang ◽  
...  
Keyword(s):  
T Cells ◽  
Chronic Pancreatitis ◽  
Immune Cell ◽  
Therapeutic Potential ◽  
Ros Generation ◽  
Hydrogen Treatment ◽  
Tissue Destruction ◽  
Sod Activity ◽  
Chronic Pancreatitis Patient

Background/Aims: Chronic pancreatitis is an inflammatory disease of the pancreas characterized by progressive tissue destruction and fibrogenesis. The development of chronic pancreatitis is associated with immune cell dysregulation. Currently, the specific and effective treatment of chronic pancreatitis remains absent. Methods: By using an L-arginine induced chronic pancreatitis mouse model, we tested the therapeutic potential of hydrogen, a strong hydroxyl radicals scavenger, in the chronic pancreatitis model. Tissue inflammation, damage and fibrosis were analyzed on HE, TUNEL, MPO, and sirius staining. Pancreas levels of MDA content, SOD activity, TNF-α , IL-10 cytokine expression and serum amylase and lipase activity were determined by ELISA and absorbance assay. Apoptosis, T cells subtype proportion and intracellular level of reactive oxygen species (ROS) were analyzed by flow cytometry. Tregs adoptive transfer and CD25 neutralization were used to validate the role of Tregs in chronic pancreatitis. Results: We found that hydrogen treatment significantly improved multiple symptoms of chronic pancreatitis. The number of Tregs was reduced in chronic pancreatitis mice, while hydrogen treatment restored the Treg loss by L-arginine administrations. Depletion of Tregs abolished the protective effect of hydrogen treatment in chronic pancreatitis. In vitro study showed that hydrogen blocked ROS generation in Tregs and promoted Tregs survival. Conclusion: Hydrogen treatment showed reliable benefits in controlling the severity of chronic pancreatitis. Our study supported that hydrogen could be used as a novel treatment in chronic pancreatitis patient in the future.

scholarly journals Pancreatic stenting perhormed in a chronic pancreatitis patient with complete situs inversus

2008 ◽  
Vol 73 (2) ◽  
pp. 192-193
Author(s):  
Hideaki Honda ◽  
Hiroyuki Miyatan ◽  
Masatoshi Ikeda ◽  
Shinya Ushimaru ◽  
Toru Takamatsu ◽  
...  
Keyword(s):  
Chronic Pancreatitis ◽  
Situs Inversus ◽  
Chronic Pancreatitis Patient ◽  
Complete Situs Inversus

Evaluation clinical and biochemical characteristics of patients with chronic pancreatitis

2019 ◽  
pp. 89-96
Author(s):  
Khanh Vinh ◽  
Trung Nam Phan ◽  
Van Huy Tran
Keyword(s):  
Diabetes Mellitus ◽  
Abdominal Pain ◽  
Chronic Pancreatitis ◽  
Endoscopic Ultrasound ◽  
Clinical Characteristics ◽  
Structural Changes ◽  
Serum Lipase ◽  
Heavy Smoking ◽  
Biochemical Characteristics ◽  
Chronic Pancreatitis Patient

Objective: Chronic pancreatitis is a chronic, progressive, irreversible benign inflammatory process, resulting in structural changes with disorders of functional exocrine and endocrine parenchyma by a fibrotic and inflammatory tissue. Based on clinical characteristics and morphology to diagnose chronic pancreatitis. This study was assessing the clinical, biochemical characteristics of chronic pancreatitis patients; and evaluating the relationship between grade chronic pancreatitis and clinical, biochemical characteristics. Subjects and methods: A cross-sectional study was conducted on 51 patients with chronic pancreatitis diagnosed based on Rosemont Criteria in endoscopic ultrasound and Japanese clinical diagnostic criteria for chronic pancreatitis. Results: The prevalence of male was higher than female (70.5%/29.5%) and most common in the age group of 41 - 60 about 55%. The prevalence of patients with a history of alcohol abuse was highest with 31.3%, smoking cigarette more than 20 pack-years about 4.1%. The clinical characteristics of patients with chronic pancreatitis are highest in abdominal pain about 66.6% and lowest in jaundice about 5.8%. About biochemical characteristics, an increase of amylase, lipase were found in 29.5% and 31.5%, respectively. The diabetes mellitus were found in 25.6%. A statistically significative difference of abdominal pain was found between the chronic pancreatitis and early chronic pancreatitis patients (p=0.0003). Mean level of lipase in chronic pancreatitis patient is 33.7 U/L(3.3-195) and early chronic pancreatitis patient is 53.1 U/L (20.5-109), with significiant difference (p=0.04). Conclusions: Alcohol consumption, heavy smoking and diabetes mellitus were the most important risk factors of chronic pancreatitis. Abdominal pain was constant while hyperamylasemia and hyperlipasemia was found only in 29.5% and 31.5% patients. Rate of abdominal pain and mean level of serum lipase were different between chronic pancreatitis and early chronic pancreatitis patients. Key words: chronic pancreatitis, endoscopic ultrasound

Pseudoaneurysm in a chronic pancreatitis patient: report of a case, with emphasis on contrast-enhanced sonograms

2009 ◽  
Vol 37 (2) ◽  
pp. 75-79 ◽  
Author(s):  
Yoko Ohyama ◽  
Hideaki Ishida ◽  
Chioko Yoshida ◽  
Jyunko Konno ◽  
Takao Hoshino ◽  
...  
Keyword(s):  
Chronic Pancreatitis ◽  
Patient Report ◽  
Chronic Pancreatitis Patient ◽  
Contrast Enhanced

Endoscopic Retrograde Cholangiopancreatography

2017 ◽  
Author(s):  
Wasif Abidi ◽  
Linda S. Lee
Keyword(s):  
Chronic Pancreatitis ◽  
Endoscopic Retrograde Cholangiopancreatography ◽  
Acute Cholangitis ◽  
Bile Leak ◽  
Therapeutic Interventions ◽  
Therapeutic Modality ◽  
Pancreatic Ducts ◽  
Type I ◽  
Endoscopic Retrograde ◽  
Duct Stricture

Endoscopic retrograde cholangiopancreatography (ERCP) is a specialized endoscopic procedure to view the biliary and pancreatic ducts fluoroscopically. First introduced in the 1970s as a diagnostic tool, ERCP has since evolved primarily into a therapeutic modality and is today regarded as the premier tool for performing therapeutic interventions involving the biliary and pancreatic ductal systems. Relatively complex, ERCP requires advanced training. Although generally considered safe, it does carry a risk of significant complications, including pancreatitis; thus, the most important factor to mitigate complications is to ensure the presence of an appropriate indication for the procedure. This review addresses the indications (e.g., disorders of the major duodenal papilla, biliary diseases, and pancreatic diseases), contraindications, protocol, and complications of ERCP, as well as an overview of the tools available for ERCP procedures. Figures show ampullary adenomas, choledocholithiasis, Mirizzi syndrome, benign common bile duct stricture, primary sclerosing cholangitis, malignant biliary stricture, bile leak, type I and III choledochal cysts, chronic pancreatitis, pancreatic ductal disruption, classic fish-mouth appearance of the papilla in a patient with main duct intraductal papillary mucinous neoplasm, pancreas divisum, side-viewing duodenoscope used for ERCP, and selected tools of ERCP. Tables list the Rome III criteria, risk-stratifying patients for choledocholithiasis, diagnostic criteria for acute cholangitis, choledochal cyst classification, and the Cambridge classification system for chronic pancreatitis. This review contains 15 highly rendered figures, 5 tables, and 77 references.

scholarly journals Combined Medical Treatment Of Chronic Pancreatitis

2015 ◽  
Vol 69 (1-2) ◽  
pp. 20-26
Author(s):  
Larisa Umnova ◽  
Grigorijs Orļikovs ◽  
Jūlija Voicehovska ◽  
Vladimirs Voicehovskis ◽  
Eduards Krustiņš
Keyword(s):  
Chronic Pancreatitis ◽  
Medical Treatment ◽  
Therapy Group ◽  
Life Assessment ◽  
Patient Treatment ◽  
Quality Of Life Assessment ◽  
Chronic Pancreatitis Patient ◽  
Bowel Movements ◽  
Long Course

AbstractThe aim of the study was to determine the most effective medical treatment of patients with chronic pancreatitis, by using either pancreatin alone or in combination with proton pump inhibitor (PPI) or PPI and non-steroidal anti-inflammatory drug (NSAID). Patients with chronic pancreatitis, who did not require a surgical treatment, received medical treatment for a one–month period: 20 patients received pancreatin monotherapy; 48 patients were given a combination of pancreatin and PPI; 38 patients were treated with a combination of pancreatin, PPI and NSAID (PNP therapy group). In comparison with other groups, patients in the PNP therapy group showed improvement in body mass index, abdominal pain, bowel movements, chronic pancreatitis severity, as well as their quality of life assessment (p< 0.05). The combination of pancreatin, PPI and NSAID was the most effective among those applied in chronic pancreatitis patient treatment. A one–month long course of this therapy was safe and did not cause any significant adverse effects. The combination of pancreatin, PPI and NSAID for treatment of chronic pancreatitis can be recommended, as it is based on pathogenesis of the disease, effective, safe and economically advantageous.

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