SerumWisteria floribundaagglutinin-positive Mac-2-binding protein levels and liver fibrosis: A meta-analysis

2017 ◽  
Vol 32 (12) ◽  
pp. 1922-1930 ◽  
Author(s):  
Kiyoaki Ito ◽  
Kenta Murotani ◽  
Yukiomi Nakade ◽  
Tadahisa Inoue ◽  
Haruhisa Nakao ◽  
...  
Keyword(s):  
Liver Fibrosis ◽  
Binding Protein ◽  
Meta Analysis ◽  
Protein Levels

scholarly journals Markers of Monocyte Activation, Inflammation, and Microbial Translocation Are Associated with Liver Fibrosis in Alcohol Use Disorder

2021 ◽  
Vol 10 (16) ◽  
pp. 3496
Author(s):  
Daniel Fuster ◽  
Xavier Garcia-Calvo ◽  
Oriol Farré ◽  
Paola Zuluaga ◽  
Ferran Bolao ◽  
...  
Keyword(s):  
Alcohol Use ◽  
Liver Fibrosis ◽  
Alcohol Use Disorder ◽  
Binding Protein ◽  
Correlation Coefficients ◽  
Microbial Translocation ◽  
Monocyte Activation ◽  
Protein Levels ◽  
Markers Of Inflammation ◽  
Lps Binding

Background: The association between markers of inflammation (interleukin (IL)-6 and IL-10), monocyte activation (sCD163 and sCD14), and microbial translocation (lipopolysaccharide (LPS) and LPS binding protein) and liver fibrosis in patients with alcohol use disorder (AUD) and no overt liver disease is not well established. Methods: We studied patients admitted for treatment of AUD at two hospitals in Barcelona. Advanced liver fibrosis (ALF) was defined as FIB-4 > 3.25. Results: A total of 353 participants (76.3% male) were included and 94 (26.5%) had ALF. In adjusted correlation analyses, sCD163, sCD14, IL-6, IL-10, and LPS binding protein levels directly correlated with FIB-4 values (adjusted correlation coefficients 0.214, 0.452, 0.317, 0.204, and 0.171, respectively). However, LPS levels were inversely associated with FIB-4 (−0.283). All plasma marker levels in the highest quartile, except LPS, were associated with ALF (sCD163, sCD14, IL-6, IL-10, and LPS binding protein: adjusted odds ratio (aOR) 11.49 (95% confidence interval 6.42–20.56), 1.87 (1.11–3.16), 2.99 (1.79–5.01), 1.84 (1.11–3.16), and 2.13 (1.30–3.50), respectively). Conversely, LPS levels in the lowest quartile were associated with ALF (aOR 2.58 (1.48–4.58), p < 0.01). Conclusion: In AUD patients, plasma levels of the markers of inflammation, monocyte activation, and microbial translocation are associated with ALF.

Mac‐2 Binding Protein Glycan Isomer as non‐invasive tool to assess liver fibrosis in children with chronic liver disease

2021 ◽  
Author(s):  
Ola G Behairy ◽  
Soha A El‐Gendy ◽  
Dalia Y Ibrahim ◽  
Amira I Mansour ◽  
Ola S El‐Shimi
Keyword(s):  
Liver Disease ◽  
Liver Fibrosis ◽  
Chronic Liver Disease ◽  
Binding Protein ◽  
Chronic Liver ◽  
Non Invasive

Hepatic Stellate Cell as a Mac‐2‐binding Protein‐producing Cell in Patients with Liver Fibrosis

2021 ◽  
Author(s):  
Dolgormaa Gantumur ◽  
Norifumi Harimoto ◽  
Ryo Muranushi ◽  
Kouki Hoshino ◽  
Chingun Batbayar ◽  
...  
Keyword(s):  
Liver Fibrosis ◽  
Hepatic Stellate Cell ◽  
Stellate Cell ◽  
Binding Protein

Growth hormone-binding protein levels: Studies of children with short stature

Metabolism ◽  
1994 ◽  
Vol 43 (3) ◽  
pp. 357-359 ◽  
Author(s):  
Nelly Mauras ◽  
Lena M.S. Carlsson ◽  
Suzanne Murphy ◽  
Thomas J. Merimee
Keyword(s):  
Growth Hormone ◽  
Short Stature ◽  
Binding Protein ◽  
Hormone Binding ◽  
Protein Levels ◽  
Growth Hormone Binding Protein ◽  
Hormone Binding Protein
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