Gastrointestinal: Zollinger-Ellison Syndrome: A rare cause of chronic diarrhea and abdominal pain

2017 ◽  
Vol 32 (7) ◽  
pp. 1281-1281 ◽  
Author(s):  
B Anderson ◽  
S Sweetser
Keyword(s):  
Abdominal Pain ◽  
Chronic Diarrhea ◽  
Zollinger Ellison Syndrome

scholarly journals Terminal ileum of patients who underwent colonoscopy: endoscopic, histologic and clinical aspects

2009 ◽  
Vol 46 (2) ◽  
pp. 102-106 ◽  
Author(s):  
Marcelo Maia Caixeta de Melo ◽  
Patrícia Maluf Cury ◽  
Luiz Sérgio Ronchi ◽  
Francisco de Assis Gonçalves-Filho ◽  
Geni Satomi Cunrath ◽  
...  
Keyword(s):  
Abdominal Pain ◽  
Terminal Ileum ◽  
Chronic Diarrhea ◽  
Clinical Importance ◽  
Histological Evaluation ◽  
Clinical Aspects ◽  
Ileal Mucosa ◽  
Histological Alterations ◽  
Kappa Test ◽  
A Prospective Study

CONTEXT: For the diagnosis of the diseases which affect the terminal ileum, the colonoscopy allows macroscopic evaluation and the performing of biopsies. Studies with criteria for the endoscopic and histological characterization of this segment are scarce and there are still some doubts about the need of biopsies in patients with normal ileoscopy. OBJECTIVE: Study the terminal ileum of patients who underwent colonoscopy considering: endoscopic and histological correlation; agreement between results of the initial histological evaluation and slides review, and the chance of subjects with normal ileoscopy with abdominal pain and/or chronic diarrhea to show histological alterations. METHODS: In a prospective study, 111 patients who presented smooth mucosa without enanthema in the endoscopic exam of the terminal ileum were selected. Biopsies of the ileal mucosa of such patients were performed, being the slides routinely examined and reviewed afterwards. RESULTS: The correlation between patients with normal ileoscopy and ileum with preserved histological architecture was of 99.1%. The agreement between initial histological evaluation and slides review calculated by the Kappa test was 0.21. In patients with abdominal pain and/or chronic diarrhea, the chance of showing histological alterations was 2.5 times higher than the others. CONCLUSIONS: The correlation between endoscopic and histological findings was high. The agreement between the initial histologic evaluation and slides review was not satisfactory. The chance of subjects with normal ileoscopy with abdominal pain and/or chronic diarrhea, showing histological alterations was higher in relation to the asymptomatic ones or with other symptoms, although the clinical importance of this datum was not evaluated.

scholarly journals Association between Inflammatory Bowel Disease and Pancreatitis: A PRISMA-Compliant Systematic Review

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Pengfan Li ◽  
Kanjun Chen ◽  
Zheng Mao ◽  
Yue Luo ◽  
Yan Xue ◽  
...  
Keyword(s):  
Systematic Review ◽  
Inflammatory Bowel Disease ◽  
Weight Loss ◽  
Acute Pancreatitis ◽  
Abdominal Pain ◽  
Chronic Pancreatitis ◽  
Bowel Disease ◽  
Chronic Diarrhea ◽  
Inflammatory Bowel ◽  
Correlative Studies

Background/Objectives. This systematic review was conducted to investigate the association between pancreatitis and IBD. Methods. MEDLINE, Embase, and CENTRAL were systematically searched for correlative studies till 2 November 2019. RevMan5.3 was used to estimate relevance. Results. Three studies with 166008 participants were included. The risk of pancreatitis significantly increased in the patients with CD (OR, 3.40; 95% CI, 2.70-4.28; P<0.00001) and UC (OR, 2.49; 95% CI, 1.91-3.26; P<0.00001). Increased risks of CD (OR, 12.90; 95% CI, 5.15-32.50; P<0.00001) and UC (OR, 2.80; 95% CI, 1.00-7.86; P=0.05) were found in patients with chronic pancreatitis. As for patients with acute pancreatitis, there were significant association of CD (OR, 3.70; 95% CI, 1.90-7.60; P=0.0002), but were not UC. Conclusions. The evidence confirmed an association between pancreatitis and IBD. When pancreatitis patients have chronic diarrhea and mucus blood stool or IBD patients have repeated abdominal pain and weight loss, they should consult pancreatic and gastrointestinal specialists.

Selective Immunoglobulin A Deficiency and Intestinal Nodular Lymphoid Hyperplasia: Correction of Diarrhea with Antibiotics and Plasma

PEDIATRICS ◽  
1968 ◽  
Vol 42 (5) ◽  
pp. 833-837
Author(s):  
Joyce D. Gryboski ◽  
Thomas W. Self ◽  
Arthur Clemett ◽  
Teodoro Herskovic
Keyword(s):  
Small Intestine ◽  
Abdominal Pain ◽  
Chronic Diarrhea ◽  
Immunoglobulin A ◽  
Lymphoid Hyperplasia ◽  
Fresh Frozen Plasma ◽  
Nodular Lymphoid Hyperplasia ◽  
Fresh Frozen ◽  
Frozen Plasma ◽  
Plasma Infusions

A 13-year-old boy with chronic diarrhea and abdominal pain since 6 months of age, and recurrent fevers since 12% years of age, was found to have deficiency of IgA and nodular lymphoid hyperplasia of the small intestine. This disorder was similar to that of "dysgammaglobulinemia and intestinal lymphoid hyperplasia" described in adults in 1966. An associated giardiasis was eliminated by atabrine therapy and a malabsorption syndrome, cleared after treatment with tetracycline. Diarrhea and abdominal pain were not alleviated until he was treated with monthly fresh frozen plasma infusions. It is to be emphasized that other forms of chronic diarrhea not related to immunoglobuun deficiencies do not respond to this type of therapy.

Zollinger-Ellison Syndrome in a Nineyear -old Child: A Case Report and Review of this Entity in Childhood

PEDIATRICS ◽  
1971 ◽  
Vol 47 (3) ◽  
pp. 594-598
Author(s):  
Richard M. Buchta ◽  
J. M. Kaplan
Keyword(s):  
Abdominal Pain ◽  
Case Report ◽  
Clinical Data ◽  
Islet Cell ◽  
Islet Cell Tumor ◽  
Cell Tumor ◽  
Gastric Hypersecretion ◽  
Zollinger Ellison Syndrome ◽  
History Of ◽  
Epigastric Abdominal Pain

In 1955, Zollinger and Ellison1 described a syndrome consisting of peptic ulceration, marked gastric hypersecretion, and non-beta islet cell tumor of the pancreas. Although there have been over 300 cases in the adult literature2-5 only 19 patients, 16 years old or younger have been reported. We add one more child to this growing list and review the clinical data of the known cases described. Case Report The patient (R.L.) was a 9-year-old Negro male with a 7-month history of intermittent episodes of mid-epigastric abdominal pain. The pain was somewhat relieved by eating, or the use of antispasmodics. During this period of time, the child had occasional episodes of vomiting, but no melena or hematemesis.

scholarly journals Zollinger Ellison Syndrome in a Patient with Multiple Endocrine Neoplasia Type 1: A Classic Presentation

2019 ◽  
Vol 2019 ◽  
pp. 1-4
Author(s):  
Ishani Shah ◽  
Neil Vyas ◽  
Kambiz S. Kadkhodayan
Keyword(s):  
Multiple Endocrine Neoplasia ◽  
Multiple Endocrine Neoplasia Type ◽  
Chronic Diarrhea ◽  
Wide Spectrum ◽  
Pancreatic Neuroendocrine Tumor ◽  
Watery Diarrhea ◽  
Ulcer Disease ◽  
Endocrine Neoplasia ◽  
Zollinger Ellison Syndrome

Zollinger Ellison Syndrome (ZES) is characterized by a wide spectrum of conditions including severe gastroesophageal reflux disease, peptic ulcer disease, watery diarrhea, and weight loss. We present a case of a 60-year-old woman being evaluated for severe dyspepsia, vomiting, and chronic diarrhea, who was diagnosed to have ZES associated with a pancreatic neuroendocrine tumor, in the setting of multiple endocrine neoplasia (MEN) type 1. Although cases of ZES have been reported previously, we believe that our case is a classic presentation of ZES diagnosed on the basis of typical radiologic, endoscopic, and endosonographic features.

Chronic Diarrhea Responding to Proton Pump Inhibitors: A Clinical Sign of Zollinger-Ellison Syndrome

2009 ◽  
Vol 122 (11) ◽  
pp. e9-e10 ◽  
Author(s):  
Vincent Zimmer ◽  
Martin K. Schilling ◽  
Arno Buecker ◽  
Frank Lammert ◽  
Jochen Raedle
Keyword(s):  
Clinical Sign ◽  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Chronic Diarrhea ◽  
Zollinger Ellison Syndrome

Small-bowel bacterial overgrowth in children with chronic diarrhea, abdominal pain, or both

1996 ◽  
Vol 128 (2) ◽  
pp. 203-207 ◽  
Author(s):  
D. de Boissieu ◽  
M. Chaussain ◽  
J. Badoual ◽  
J. Raymond ◽  
C. Dupont
Keyword(s):  
Abdominal Pain ◽  
Small Bowel ◽  
Chronic Diarrhea ◽  
Bacterial Overgrowth ◽  
Small Bowel Bacterial Overgrowth
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