Randomized clinical trial comparing 10- or 14-day sequential therapy and 10- or 14-day concomitant therapy for the first line empirical treatment ofHelicobacter pyloriinfection

2017 ◽  
Vol 32 (3) ◽  
pp. 589-594 ◽  
Author(s):  
Sung Min Park ◽  
Joon Sung Kim ◽  
Byung-Wook Kim ◽  
Jeong-Seon Ji ◽  
Hwang Choi
Keyword(s):  
Clinical Trial ◽  
Randomized Clinical Trial ◽  
Sequential Therapy ◽  
Empirical Treatment ◽  
Concomitant Therapy ◽  
First Line

Tofacitinib with Concomitant Therapy for Vitiligo: protocol for a phase II randomized clinical trial (Preprint)

2021 ◽  
Author(s):  
Megha Joshi
Keyword(s):  
Quality Of Life ◽  
Clinical Trial ◽  
Adverse Effects ◽  
Randomized Clinical Trial ◽  
Concomitant Therapy ◽  
Autoimmune Destruction ◽  
Novel Treatment ◽  
Narrowband Uvb ◽  
High Level

UNSTRUCTURED Vitiligo is the most common acquired skin depigmentation disorder that affects about 35 million people worldwide. This debilitating disease causes autoimmune destruction of the epidermal melanocytes, forming macules and patches of hypopigmented skin, which causes considerable stigma and a decrease in the quality of life in affected individuals. Narrowband UVB (NB-UVB) is the preferred treatment right now, alone or in combination with immunomodulator drugs. It is not 100% effective and has many adverse effects, as noted in the literature previously. The addition of topical Tofacitinib to the already present therapy has the potential to be a novel treatment with a high level of efficacy for vitiligo. This can significantly improve the quality of life in the millions of people suffering from vitiligo worldwide.

scholarly journals Randomized Clinical Trial of First‐Line Genome Sequencing in Pediatric White Matter Disorders

2020 ◽  
Vol 88 (2) ◽  
pp. 264-273 ◽  
Author(s):  
Adeline Vanderver ◽  
Geneviève Bernard ◽  
Guy Helman ◽  
Omar Sherbini ◽  
Ryan Boeck ◽  
...  
Keyword(s):  
Clinical Trial ◽  
White Matter ◽  
Randomized Clinical Trial ◽  
Genome Sequencing ◽  
First Line ◽  
White Matter Disorders
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