Screening of the freeze‐drying protective agent for high quality milk beer yeast ( Kluyveromyces marxianus) and optimization of freeze‐drying process conditions

2021 ◽  
Author(s):  
Liang Wang ◽  
Mingying He ◽  
Tao Wu ◽  
Kangye Yang ◽  
Yulian Wang ◽  
...  
Keyword(s):  
Kluyveromyces Marxianus ◽  
Freeze Drying ◽  
Process Conditions ◽  
Protective Agent ◽  
Drying Process ◽  
High Quality ◽  
Beer Yeast

scholarly journals The Freeze-Drying of Foods—The Characteristic of the Process Course and the Effect of Its Parameters on the Physical Properties of Food Materials

Foods ◽  
2020 ◽  
Vol 9 (10) ◽  
pp. 1488 ◽  
Author(s):  
Dorota Nowak ◽  
Ewa Jakubczyk
Keyword(s):  
Mechanical Properties ◽  
Physical Properties ◽  
Structural Properties ◽  
Freeze Drying ◽  
Process Conditions ◽  
Drying Process ◽  
High Quality ◽  
Freeze Dried ◽  
Secondary Drying ◽  
Selection Of

Freeze-drying, also known as lyophilization, is a process in which water in the form of ice under low pressure is removed from a material by sublimation. This process has found many applications for the production of high quality food and pharmaceuticals. The main steps of the freeze-drying process, such as the freezing of the product and primary and secondary drying, are described in this paper. The problems and mechanisms of each step of the freeze-drying process are also analyzed. The methods necessary for the selection of the primary and secondary end processes are characterized. The review contains a description of the effects of process conditions and the selected physical properties of freeze-dried materials, such as structural properties (shrinkage and density porosity), color, and texture. The study shows that little attention is given to the mechanical properties and texture of freeze-dried materials obtained from different conditions of the lyophilization process.

Development of a Functional Beverage Formulation with High Protein Content, Inulin and Stevia

2011 ◽  
Vol 7 (3) ◽  
Author(s):  
Laura T Rodriguez Furlán ◽  
Antonio Pérez Padilla ◽  
Mercedes Campderros
Keyword(s):  
Freeze Drying ◽  
Protein Supplement ◽  
Protective Agent ◽  
Protein Concentrate ◽  
High Solubility ◽  
Food Ingredient ◽  
High Quality ◽  
High Protein Content ◽  
Bovine Plasma ◽  
Low Carbohydrate

A beverage formulation with proteins of high quality, inulin, Stevia and C vitamin has been prepared. The protein source was bovine plasma which was concentrated and demineralized by a combined membrane methodologies as microfiltration, ultrafiltration and discontinues diafiltration. The use of inulin as protective agent to prevent protein concentrate denaturation during freeze-drying was assayed. The inulin is a versatile food ingredient and it also has health benefits. The powder obtained has improved sensory characteristic and high solubility. Stevia has been added as sweetness, being a low-carbohydrate, low-sugar food alternative. The formulation could be destined as protein supplement with functional properties or for special dietary use.

Effect of Freeze-Drying Process Conditions on the Stability of Nanoparticles

2004 ◽  
Vol 22 (1-2) ◽  
pp. 335-346 ◽  
Author(s):  
M. J. Choi ◽  
S. Briançon ◽  
J. Andrieu ◽  
S. G. Min ◽  
H. Fessi
Keyword(s):  
Freeze Drying ◽  
Process Conditions ◽  
Drying Process ◽  
The Stability

Video real-time imaging of artificial membranes during freeze-drying by cryo-electron microscopy

1988 ◽  
Vol 46 ◽  
pp. 16-17
Author(s):  
Alan S. Rudolph ◽  
Ronald R. Price
Keyword(s):  
Real Time ◽  
Self Assembly ◽  
Freeze Drying ◽  
Video Capture ◽  
Drying Process ◽  
Artificial Membranes ◽  
The Past ◽  
Cryo Electron Microscopy ◽  
Spherical Structures ◽  
Capture Techniques

We have employed cryoelectron microscopy to visualize events that occur during the freeze-drying of artificial membranes by employing real time video capture techniques. Artificial membranes or liposomes which are spherical structures within internal aqueous space are stabilized by water which provides the driving force for spontaneous self-assembly of these structures. Previous assays of damage to these structures which are induced by freeze drying reveal that the two principal deleterious events that occur are 1) fusion of liposomes and 2) leakage of contents trapped within the liposome [1]. In the past the only way to access these events was to examine the liposomes following the dehydration event. This technique allows the event to be monitored in real time as the liposomes destabilize and as water is sublimed at cryo temperatures in the vacuum of the microscope. The method by which liposomes are compromised by freeze-drying are largely unknown. This technique has shown that cryo-protectants such as glycerol and carbohydrates are able to maintain liposomal structure throughout the drying process.

scholarly journals Post-Processing Techniques for the Improvement of Liposome Stability

Pharmaceutics ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1023
Author(s):  
Ji Young Yu ◽  
Piyanan Chuesiang ◽  
Gye Hwa Shin ◽  
Hyun Jin Park
Keyword(s):  
Freeze Drying ◽  
Protective Agent ◽  
Post Processing ◽  
Additional Process ◽  
Spray Freeze Drying ◽  
The Stability ◽  
Processing Techniques ◽  
The Impact ◽  
Self Aggregation ◽  
Liposome Stability

Liposomes have been utilized as a drug delivery system to increase the bioavailability of drugs and to control the rate of drug release at the target site of action. However, the occurrence of self-aggregation, coalescence, flocculation and the precipitation of aqueous liposomes during formulation or storage can cause degradation of the vesicle structure, leading to the decomposition of liposomes. To increase the stability of liposomes, post-processing techniques have been applied as an additional process to liposomes after formulation to remove water and generate dry liposome particles with a higher stability and greater accessibility for drug administration in comparison with aqueous liposomes. This review covers the effect of these techniques including freeze drying, spray drying and spray freeze drying on the stability, physicochemical properties and drug encapsulation efficiency of dry liposomes. The parameters affecting the properties of liposomes during the drying process are also highlighted in this review. In addition, the impact of using a protective agent to overcome such limitations of each process is thoroughly discussed through various studies.

scholarly journals Strengthening of Porcine Plasma Protein Superabsorbent Materials through a Solubilization-Freeze-Drying Process

Polymers ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 772
Author(s):  
Estefanía Álvarez-Castillo ◽  
Carlos Bengoechea ◽  
Antonio Guerrero
Keyword(s):  
Water Uptake ◽  
Plasma Protein ◽  
Freeze Drying ◽  
Meat Industry ◽  
Drying Process ◽  
Uptake Capacity ◽  
Water Uptake Capacity ◽  
Protein Flour ◽  
Hydrophilic Materials ◽  
By Products

The replacement of common acrylic derivatives by biodegradable materials in the formulation of superabsorbent materials would lessen the associated environmental impact. Moreover, the use of by-products or biowastes from the food industry that are usually discarded would promote a desired circular economy. The present study deals with the development of superabsorbent materials based on a by-product from the meat industry, namely plasma protein, focusing on the effects of a freeze-drying stage before blending with glycerol and eventual injection molding. More specifically, this freeze-drying stage is carried out either directly on the protein flour or after its solubilization in deionized water (10% w/w). Superabsorbent materials obtained after this solubilization-freeze-drying process display higher Young’s modulus and tensile strength values, without affecting their water uptake capacity. As greater water uptake is commonly related to poorer mechanical properties, the proposed solubilization-freeze-drying process is a useful strategy for producing strengthened hydrophilic materials.

Comparative Study of Different Process Conditions of Freeze Drying of ‘Murtilla’ Berry

2010 ◽  
Vol 28 (12) ◽  
pp. 1416-1425 ◽  
Author(s):  
A. Reyes ◽  
V. Bubnovich ◽  
R. Bustos ◽  
M. Vásquez ◽  
R. Vega ◽  
...  
Keyword(s):  
Comparative Study ◽  
Freeze Drying ◽  
Process Conditions
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