Physical, mechanical, optical, barrier and antioxidant properties of sodium alginate‐aloe vera biocomposite film

2021 ◽  
Author(s):  
Alina Hadi ◽  
Anjum Nawab ◽  
Feroz Alam ◽  
Kishwar Zehra
Keyword(s):  
Sodium Alginate ◽  
Antioxidant Properties ◽  
Aloe Vera ◽  
Optical Barrier ◽  
Biocomposite Film

scholarly journals Optimization of Clinacanthus nutans Biodegradable Analgesic Patch

2018 ◽  
Vol 13 (12) ◽  
pp. 1934578X1801301
Author(s):  
Em-on Chaiprateep ◽  
Chalermsak Thavornwat
Keyword(s):  
Sodium Alginate ◽  
Aloe Vera ◽  
Cost Effective ◽  
Physicochemical Characteristics ◽  
Total Quality ◽  
Weight Variation ◽  
Accelerated Stability ◽  
Clinacanthus Nutans ◽  
Cost Of Production

This paper aims to analyze and perfect the C. nutans-based biodegradable patch for analgesic employing a design of experiment (DoE) by Minitab version 18 program. Fifty-four full factorial design formulation were used to determine three factors and levels. They are made up of various concentration of 2%, 4%, and 6% of sodium alginate (ALG-Na) and Aloe vera juice. The sodium alginate (ALG-Na) and Aloe vera juice play the role of natural film former and terpenes act as permeation enhancers (eugenol, anethole, limonene). The Physicochemical characteristics include weight variation, thickness, surface pH, max stress, % elongation, mucoadhesive time and cost of production. These physicochemical properties were all investigated. The results show that the combination of 6% of sodium alginate (ALG-Na) and anethole produced the total quality (max stress, % elongation, mucoadhesive time, cost of production) (R2 adj > 87.95%, p<0.01). From the Accelerated stability test performed, it was observed that the weight and thickness of the patch were not statistically significantly different (p<0.05). This is a favorable physicochemical property. It is also a cost-effective profile for biodegradable dermal analgesic patches commercial product further.

scholarly journals CrudeAloe veraGel Shows Antioxidant Propensities and Inhibits Pancreatic Lipase and Glucose MovementIn Vitro

2016 ◽  
Vol 2016 ◽  
pp. 1-9 ◽  
Author(s):  
Urmeela Taukoorah ◽  
M. Fawzi Mahomoodally
Keyword(s):  
Pancreatic Lipase ◽  
Antioxidant Properties ◽  
Aloe Vera ◽  
Reducing Power ◽  
Kinetic Studies ◽  
Total Phenolic ◽  
Anthocyanin Content ◽  
Maximal Velocity ◽  
Inhibitory Potential

Aloe veragel (AVG) is traditionally used in the management of diabetes, obesity, and infectious diseases. The present study aimed to investigate the inhibitory potential of AVG againstα-amylase,α-glucosidase, and pancreatic lipase activityin vitro. Enzyme kinetic studies using Michaelis-Menten (Km) and Lineweaver-Burk equations were used to establish the type of inhibition. The antioxidant capacity of AVG was evaluated for its ferric reducing power, 2-diphenyl-2-picrylhydrazyl hydrate scavenging ability, nitric oxide scavenging power, and xanthine oxidase inhibitory activity. The glucose entrapment ability, antimicrobial activity, and total phenolic, flavonoid, tannin, and anthocyanin content were also determined. AVG showed a significantly higher percentage inhibition (85.56±0.91) of pancreatic lipase compared to Orlistat. AVG was found to increase the Michaelis-Menten constant and decreased the maximal velocity (Vmax) of lipase, indicating mixed inhibition. AVG considerably inhibits glucose movement across dialysis tubes and was comparable to Arabic gum. AVG was ineffective against the tested microorganisms. Total phenolic and flavonoid contents were66.06±1.14 (GAE)/mg and60.95±0.97 (RE)/mg, respectively. AVG also showed interesting antioxidant properties. The biological activity observed in this study tends to validate some of the traditional claims of AVG as a functional food.

scholarly journals Aloe barbadensis: A Plant of Nutricosmetic Interest

2020 ◽  
Vol 15 (7) ◽  
pp. 1934578X2093274
Author(s):  
S Laneri ◽  
RM Di Lorenzo ◽  
A Bernardi ◽  
A Sacchi ◽  
I Dini
Keyword(s):  
Healthy Adult ◽  
Imaging Techniques ◽  
Antioxidant Properties ◽  
Aloe Vera ◽  
Transepidermal Water Loss ◽  
Barrier Effect ◽  
Aloe Barbadensis ◽  
Skin Imaging ◽  
The Face ◽  
Adult Volunteers

Aloe barbadensis Miller (Aloe Vera Linne) products have long been employed in health foods and for medical purposes. It has anti-inflammatory, antifungal, antioxidant properties, which indicates excellent potential in antiaging cosmetic and skin protection products. The objective of this study is to evaluate the antiaging efficacy of dermocosmetic formulations containing A. barbadensis extract on young and mature skin using biophysical and skin imaging techniques. Twenty healthy adult volunteers participated in the study, aged between 20 and 65. The cream formulation, with 10% (w/w) of A. barbadensis extract, and placebo, were applied to the face of the volunteers. The effects were evaluated in terms of skin hydration and barrier effect by the measurement of transepidermal water loss (TEWL), derma firmness, and elasticity. The formulation containing A. barbadensis extract significantly improves water contained in the stratum corneum, firmness, elasticity of the skin, and decreased TEWL.

scholarly journals Nutritional and Antioxidant Properties of Mango Juice and Aloe Vera Gel and their Effect on Diabetic Rats

2020 ◽  
Vol 9 (4) ◽  
pp. 1602-1614
Keyword(s):  
Antioxidant Properties ◽  
Aloe Vera ◽  
Serum Levels ◽  
Magnesium Content ◽  
Treated Group ◽  
Serum Glucose ◽  
Diabetic Rats ◽  
Aloe Vera Gel ◽  
Mango Juice ◽  
Aloe Gel

Aloe vera gel contains several vitamins and minerals, which make it rich in antioxidants and aid in managing different chronic conditions. Aloe vera, along with other fruits, is used to produce many fruit beverages. Therefore, the present work was designed to investigate effects on the sensory, nutritional, and antioxidant properties of the juice from various combinations of Aloe gel (7.5, 15, and 25 percent) with mango juice. Some biochemical parameters of streptozotocin-induced diabetic rats were also recorded for the effects of aloe gel, mango juice, and their combination. Sensory tests showed lower acceptability for juices with a content of 25 percent Aloe vera, while other scores obtained were good and deemed satisfactory. Calcium and chromium content in 25 percent aloe vera gel treatment was significantly (p<0.05) highest for mineral content, while phosphorus, potassium, and magnesium content were lower compared to other treatments. Results also showed that mango juice content of the antioxidant activity, phenols, and flavonoids increased with rising gel concentration in the blends. The administration of aloe-mango juice has resulted in a significant decrease in serum glucose and total cholesterol compared with other diabetic groups. A significant decrease in serum levels of AST, ALT, and ALP in animals receiving Aloe-mango juice relative to mango juice group was observed. Furthermore, Aloe-mango juice treatment ameliorated the oxidative stress as demonstrated by a substantial decrease in the serum MDA level in the treated group as opposed to the diabetic mango juice group. These findings of the present investigation support the use of Aloe gel for elevating the nutritional properties of the supplemented juices; it can be recommended to consume these juices as part of a healthy diet, especially for diabetic persons.

scholarly journals Etiology, Symptomatology and Management of Black Spot of Aloe vera (Aloe barbadensis Miller) through Botanicals and Biocontrol Agents – A Brief Review

2020 ◽  
pp. 11-20
Author(s):  
Mina Kumari ◽  
P. K. Jha
Keyword(s):  
Plant Pathogens ◽  
Colletotrichum Gloeosporioides ◽  
Antioxidant Properties ◽  
Aloe Vera ◽  
Black Spot ◽  
Biocontrol Agents ◽  
Aloe Barbadensis ◽  
Yield And Quality ◽  
Serious Disease ◽  
Important Medicinal Plant

Aloe vera is an important medicinal plant of Asphodelaceae (Liliaceae) family. It is widely used owing to its wound healing, anti-inflammatory, immunity, antidiabetic, antioxidant, laxative, antibacterial, antifungal and antiviral properties. Similar to other crop plants, Aloe vera is infected by several plant pathogens that deteriorate its yield and quality. Among various fungal diseases, black spot disease caused by Colletotrichum gloeosporioides (Penz.) Penz. & Sacc. is the most serious disease which not only reduces the crop yield and market value but also the antioxidant properties and other medicinal efficacy of the plant. C. gloeosporioides is commonly controlled by chemical fungicides but due to the limitations of applying chemical control methods on medicinal plants, there is a need to look for some safe alternatives. The objective of this paper is to review the previous work on etiology, symptomatology and management of C. gloeosporioides (Penz.) Penz. & Sacc. through botanicals (natural plant extracts), biocontrol agents and some safe and ecofriendly chemicals like Azoxystrobin.

scholarly journals The Effectiveness of Aloe vera Hydrogel Against Fusobacterium nucleatum

2020 ◽  
Vol 7 (3) ◽  
pp. 118
Author(s):  
Chandra Susanto ◽  
Ermi Girsang
Keyword(s):  
Sodium Alginate ◽  
Aloe Vera ◽  
Fusobacterium Nucleatum ◽  
Inhibition Zone ◽  
Significant Inhibition ◽  
Normality Test ◽  
Significant Difference ◽  
Antimicrobial Material ◽  
Post Hoc

Bacteria can cause infectious diseases on oral health such as gingivitis and periodontitis. Scaling and rootplaning are effective against this disease, nevertheless several types of antimicrobial material can be added to increase the effectiveness of the initial treatment. Aloe vera is one of the natural antimicroba materials that is usually used. Hydrogel is a polymetric material that is stable in wet conditions, especially in the gingival sulcus. Sodium alginate is a natural polymer that is often used to produce hydrogels due to its biocompability. The aim of this study was to know the the effectiveness of Aloe vera hydrogel against Fusobacterium nucleatum by in vitro method. This research is experimental research with a total of 20 samples. The samples used were 5% and 10% sodium alginate based Aloe vera hydrogel which were placed in pure culture of F. nucleatum in MHA media for 24 hours. The inhibition zone diameter were measured using calipers. The results of the study using Shapiro-Wilk normality test showed that the data were not normally distributed. Then Kruskal Wallis test was performed which showed significant differences in each treatment group followed by Post Hoc Mann Whitney test to see a significant difference in the 5% group and 10%. Aloe vera hydrogel showed a significant inhibition against F. nucleatum bacteria at both 5% and 10% concentrations.Keywords: Alginate, Aloe vera, Antimicrobial material, Fusobacterium nucleatum, Hydrogel, Inhibitory zone

scholarly journals Improving Sodium Alginate Films Properties by Phenolic Acid Addition

Materials ◽  
2020 ◽  
Vol 13 (13) ◽  
pp. 2895
Author(s):  
Beata Kaczmarek
Keyword(s):  
Tensile Strength ◽  
Sodium Alginate ◽  
Tannic Acid ◽  
Color Change ◽  
Antioxidant Properties ◽  
Acid Mixture ◽  
Packaging Materials ◽  
Natural Polymers ◽  
Film Forming ◽  
Cross Linker

Currently, packaging materials constitute a group of the most commonly used products. Natural polymers are widely tested as potential packaging materials to replace traditional plastics. Sodium alginate is eco-friendly and reveals effective film-forming properties whereas tannic acid has been proposed as a sodium alginate cross-linker. Thin films of sodium alginate/tannic acid were obtained by solvent evaporation. Interactions between the components were determined as well as the maximum tensile strength and color change after contact with different solutions. Improvement in the physicochemical properties of the obtained films was noticed. Moreover, such films showed antioxidant properties. It may be assumed that materials based on a sodium alginate/tannic acid mixture are promising alternatives to traditional packaging materials.

scholarly journals Health Potential of Aloe vera against Oxidative Stress Induced Corneal Damage: An “In Vitro” Study

Antioxidants ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 318
Author(s):  
Ida Ceravolo ◽  
Federica Mannino ◽  
Natasha Irrera ◽  
Francesco Squadrito ◽  
Domenica Altavilla ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Antioxidant Properties ◽  
Corneal Transplantation ◽  
Aloe Vera ◽  
In Vitro Study ◽  
Corneal Dystrophy ◽  
Adjunctive Treatment ◽  
Antioxidant Compounds ◽  
Eye Drops

Fuchs endothelial corneal dystrophy (FECD) is characterized by the gradual deterioration of corneal endothelial cells (CECs) and is the most common cause of corneal transplantation worldwide. CECs apoptosis caused by oxidative stress plays a pivotal role in the pathogenesis of FECD. Antioxidant compounds have been of considerable significance as a candidate treatment in the management of corneal diseases. Based on these findings, the objective of this study was to evaluate the effects of an aloe extract with antioxidant properties, in an “in vitro” model of FECD. Human corneal epithelial (HCE) cells were preincubated with aloe extract 100 μg/mL, two hours before hydrogen peroxide (H2O2) stimulus. H2O2 challenge significantly reduced the cell viability, increased the generation of Reactive Oxygen Species (ROS) and malondialdehyde levels. Moreover, m-RNA expression and activity of Nrf-2, Catalase and Superoxide dismutase (SOD) were reduced together with an enhanced expression of IL-1β, tumor necrosis factor-α (TNF-α), IL-6, and cyclooxygenase 2 (COX-2). Furthermore, Bcl-2, Caspase-3 and Caspase-8 expression were down-regulated while Bax was up-regulated by H2O2 stimulus. Aloe extract blunted the oxidative stress-induced inflammatory cascade triggered by H2O2 and modulated apoptosis. Aloe extract defends HCE cells from H2O2-induced injury possibly due its antioxidant and anti-inflammatory activity, indicating that eye drops containing aloe extract may be used as an adjunctive treatment for FECD.

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