Climate change‐driven disease in sympatric hosts: Temporal dynamics of parasite burden and proliferative kidney disease in wild brown trout and Atlantic salmon

2021 ◽  
Author(s):  
Magnus Lauringson ◽  
Ilkka Nousiainen ◽  
Siim Kahar ◽  
Oksana Burimski ◽  
Riho Gross ◽  
...  
Keyword(s):  
Climate Change ◽  
Kidney Disease ◽  
Atlantic Salmon ◽  
Brown Trout ◽  
Temporal Dynamics ◽  
Parasite Burden ◽  
Proliferative Kidney Disease

scholarly journals Transcriptome profiling of posterior kidney of brown trout, Salmo trutta, during proliferative kidney disease

2019 ◽  
Vol 12 (1) ◽  
Author(s):  
Arun Sudhagar ◽  
Reinhard Ertl ◽  
Gokhlesh Kumar ◽  
Mansour El-Matbouli
Keyword(s):  
Immune System ◽  
Kidney Disease ◽  
Differentially Expressed Genes ◽  
Brown Trout ◽  
Salmo Trutta ◽  
Differentially Expressed ◽  
Rna Seq ◽  
Proliferative Kidney Disease ◽  
Immune System Process ◽  
Upregulated Genes

Abstract Background Tetracapsuloides bryosalmonae is a myxozoan parasite which causes economically important and emerging proliferative kidney disease (PKD) in salmonids. Brown trout, Salmo trutta is a native fish species of Europe, which acts as asymptomatic carriers for T. bryosalmonae. There is only limited information on the molecular mechanism involved in the kidney of brown trout during T. bryosalmonae development. We employed RNA sequencing (RNA-seq) to investigate the global transcriptome changes in the posterior kidney of brown trout during T. bryosalmonae development. Methods Brown trout were exposed to the spores of T. bryosalmonae and posterior kidneys were collected from both exposed and unexposed control fish. cDNA libraries were prepared from the posterior kidney and sequenced. Bioinformatics analysis was performed using standard pipeline of quality control, reference mapping, differential expression analysis, gene ontology, and pathway analysis. Quantitative real time PCR was performed to validate the transcriptional regulation of differentially expressed genes, and their correlation with RNA-seq data was statistically analyzed. Results Transcriptome analysis identified 1169 differentially expressed genes in the posterior kidney of brown trout, out of which 864 genes (74%) were upregulated and 305 genes (26%) were downregulated. The upregulated genes were associated with the regulation of immune system process, vesicle-mediated transport, leucocyte activation, and transport, whereas the downregulated genes were associated with endopeptidase regulatory activity, phosphatidylcholine biosynthetic process, connective tissue development, and collagen catabolic process. Conclusion To our knowledge, this is the first RNA-seq based transcriptome study performed in the posterior kidney of brown trout during active T. bryosalmonae development. Most of the upregulated genes were associated with the immune system process, whereas the downregulated genes were associated with other metabolic functions. The findings of this study provide insights on the immune responses mounted by the brown trout on the developing parasite, and the host molecular machineries modulated by the parasite for its successful multiplication and release.

scholarly journals Genotypic and phenotypic correlates with proliferative kidney disease-induced mortality in Atlantic salmon

2010 ◽  
Vol 89 ◽  
pp. 125-135 ◽  
Author(s):  
E Cauwelier ◽  
J Gilbey ◽  
CS Jones ◽  
LR Noble ◽  
E Verspoor
Keyword(s):  
Kidney Disease ◽  
Atlantic Salmon ◽  
Proliferative Kidney Disease

scholarly journals A brown trout ( Salmo trutta ) population faces devastating consequences due to proliferative kidney disease and temperature increase: A case study from Austria

2019 ◽  
Vol 29 (3) ◽  
pp. 465-476 ◽  
Author(s):  
Karoline Waldner ◽  
Thomas Bechter ◽  
Stefan Auer ◽  
Florian Borgwardt ◽  
Mansour El‐Matbouli ◽  
...  
Keyword(s):  
Kidney Disease ◽  
Brown Trout ◽  
Temperature Increase ◽  
Salmo Trutta ◽  
Proliferative Kidney Disease ◽  
Brown Trout Salmo Trutta

Temperature-related parasite infection dynamics: the case of proliferative kidney disease of brown trout

Parasitology ◽  
2017 ◽  
Vol 145 (3) ◽  
pp. 281-291 ◽  
Author(s):  
NICOLE STREPPARAVA ◽  
HELMUT SEGNER ◽  
ALBERT ROS ◽  
HANNA HARTIKAINEN ◽  
HEIKE SCHMIDT-POSTHAUS ◽  
...  
Keyword(s):  
Kidney Disease ◽  
Brown Trout ◽  
Salmo Trutta ◽  
Infection Intensity ◽  
Fish Host ◽  
Parasite Development ◽  
Parasite Transmission ◽  
Wildlife Diseases ◽  
Proliferative Kidney Disease ◽  
Transmission Potential

SUMMARYClimate change, in particular rising temperature, is suspected to be a major driver for the emergence of many wildlife diseases. Proliferative kidney disease of salmonids, caused by the myxozoanTetracapsuloides bryosalmonae, was used to evaluate how temperature dependence of host–parasite interactions modulates disease emergence. Brown trout (Salmo trutta fario) kept at 12 and 15 °C, were experimentally infected withT. bryosalmonae. Parasite development in the fish host and release of spores were quantified simultaneously to unravel parasite transmission potential from the vertebrate to the invertebrate host. A change to a stable plateau in infection intensity of the kidney coincided with a threshold at which spore shedding commenced. This onset of parasite release was delayed at the low temperature in accordance with reaching this infection intensity threshold, but the amount of spores released was irrespective of temperature. The production of parasite transmission stages declined with time. In conclusion, elevated temperature modifies the parasite transmission opportunities by increasing the duration of transmission stage production, which may affect the spread and establishment of the parasite in a wider range of rivers.

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