Modulation of inflammatory markers by petroleum ether fraction of Trigonella foenum‐graecum L. seed extract in ovariectomized rats

2021 ◽  
Vol 45 (4) ◽  
Author(s):  
Takkella Nagamma ◽  
Anjaneyulu Konuri ◽  
Kumar M. R. Bhat ◽  
Rajalekshmi Maheshwari ◽  
Padmanabha Udupa ◽  
...  
Keyword(s):  
Petroleum Ether ◽  
Inflammatory Markers ◽  
Seed Extract ◽  
Ovariectomized Rats ◽  
Petroleum Ether Fraction ◽  
Trigonella Foenum Graecum ◽  
Ether Fraction ◽  
Trigonella Foenum Graecum L

scholarly journals In vitro antioxidant effects of Trigonella foenum graecum (L.) Fenugreek seed extract on sheep red blood cells

2012 ◽  
Vol 6 (38) ◽  
pp. 5119-5127 ◽  
Author(s):  
Dinakaran Vasudevan ◽  
Sridharan Subhashree ◽  
Periyasamy Latha ◽  
Sudha Rani Sankaramoorthy
Keyword(s):  
Red Blood Cells ◽  
Blood Cells ◽  
Seed Extract ◽  
Trigonella Foenum Graecum ◽  
Fenugreek Seed ◽  
Sheep Red Blood Cells ◽  
Trigonella Foenum Graecum L ◽  
Antioxidant Effects

The Suppressive Effects of the Petroleum Ether Fraction fromAtractylodes lancea(Thunb.) DC. On a Collagen-Induced Arthritis Model

2016 ◽  
Vol 30 (10) ◽  
pp. 1672-1679 ◽  
Author(s):  
Renping Liu ◽  
Enwei Tao ◽  
Shuwen Yu ◽  
Bo Liu ◽  
Lingman Dai ◽  
...  
Keyword(s):  
Petroleum Ether ◽  
Collagen Induced Arthritis ◽  
Arthritis Model ◽  
Petroleum Ether Fraction ◽  
Ether Fraction

scholarly journals Isolation and bioactivity of steroids isolates from petroleum ether fraction of Chlorella sp.

2020 ◽  
Author(s):  
A. G. Fasya ◽  
N. Millati ◽  
L. M. Rahmawati ◽  
R. Iyani ◽  
A. Hanapi ◽  
...  
Keyword(s):  
Petroleum Ether ◽  
Petroleum Ether Fraction ◽  
Chlorella Sp ◽  
Ether Fraction

scholarly journals Hepatoprotective and nephroprotective effects of Trigonella foenum-graecum L. (Fenugreek) seed extract against sodium nitrite toxicity in rats

2019 ◽  
Vol 6 (5) ◽  
pp. 3142-3150 ◽  
Author(s):  
Gözde ATİLA USLU ◽  
Hamit USLU ◽  
Yasemen ADALI
Keyword(s):  
Sodium Nitrite ◽  
Feeding Habits ◽  
Interleukin 1 ◽  
Food Additives ◽  
Physiological Saline ◽  
Seed Extract ◽  
Protective Effects ◽  
Trigonella Foenum Graecum ◽  
Liver And Kidney ◽  
Trigonella Foenum Graecum L

Introduction: Feeding habits and environmental factors may rival genetic susceptibility as etiological factors related to various cancers. Humans are continuously exposed to many synthetic food additives, one of which is sodium nitrite (NaNO2). There is a direct correlation between increases in consumption of nitrite-treated products and incidence of tissue damage, hepatotoxicity, nephrotoxicity and some types of cancer. The objective of this study was to investigate the protective effects of Trigonella foenum-graecum (TFG) on NaNO2-induced hepatotoxicity and nephrotoxicity. Methods: Forty rats were randomly assigned (10 per group) to control (physiological saline solution), TFG (150 mg/kg/day), NaNO2 (80 mg/kg/day), and NaNO2+TFG (80 mg/kg/day + 150 mg/kg/day) groups. This group was offered TFG seed extract two hours before NaNO2. At the end of three months, the rats were decapitated, and blood, kidney and liver tissues were removed. Results: Three months of oral administration of NaNO2 increased serum aspartate aminotransferase (AST), alanine aminotransferase (ALT), urea, creatinine, and pro-inflammatory cytokine levels in the liver and kidney tissues [except for liver Interleukin 1 alpha (IL-1a)] of rats. Serum AST, ALT, urea, creatinine, liver IL-6, and kidney tumor necrosis factor-a (TNF-a), IL-6, IL-1a levels significantly decreased in the NaNO2+TFG group compared to the NaNO2 group. Pathological examinations, it was determined show that exogenously administered TFG could alleviate the effects of NaNO2 hepatotoxicity and nephrotoxicity. Conclusions: Our results suggest that exogenous TFG mitigates NaNO2-administration induced hepatotoxicity and nephrotoxicity. TFG extract exerted antioxidative and anti-inflammatory effects, and played a significant role in preventing hepatic and renal damage induced by chronic NaNO2 administration.  

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