Antiaging effects of rice protein hydrolysates on Drosophila melanogaster

2021 ◽  
Author(s):  
Yang Yue ◽  
Mengting Wang ◽  
Zhangping Feng ◽  
Yanyun Zhu ◽  
Jianchu Chen
Keyword(s):  
Drosophila Melanogaster ◽  
Protein Hydrolysates ◽  
Rice Protein

Rice protein hydrolysates (RPHs) inhibit the LPS-stimulated inflammatory response and phagocytosis in RAW264.7 macrophages by regulating the NF-κB signaling pathway

RSC Advances ◽  
2016 ◽  
Vol 6 (75) ◽  
pp. 71295-71304 ◽  
Author(s):  
Li Wen ◽  
Yuehua Chen ◽  
Li Zhang ◽  
Huixin Yu ◽  
Zhou Xu ◽  
...  
Keyword(s):  
Inflammatory Response ◽  
Signaling Pathway ◽  
Nuclear Translocation ◽  
Protein Hydrolysates ◽  
Rice Protein ◽  
Phagocytic Ability ◽  
Raw264.7 Macrophages ◽  
Tnf Α

Different RPH components inhibit LPS-induced NO and TNF-α production. RPHs-C-7-3 inhibits the expression of pro-inflammatory expression. RPHs-C-7-3 suppresses the LPS-stimulated phagocytic ability. RPHs-C-7-3 regulates the nuclear translocation of p65.

scholarly journals Evaluating the Antioxidants, Whitening and Antiaging Properties of Rice Protein Hydrolysates

Molecules ◽  
2021 ◽  
Vol 26 (12) ◽  
pp. 3605
Author(s):  
Hui-Ju Chen ◽  
Fan-Jhen Dai ◽  
Cheng-You Chen ◽  
Siao-Ling Fan ◽  
Ji-Hong Zheng ◽  
...  
Keyword(s):  
Antioxidant Activities ◽  
Skin Aging ◽  
Protein Hydrolysates ◽  
Total Phenolic ◽  
Rice Protein ◽  
Potential Applications ◽  
Trolox Equivalent ◽  
Dose Dependent ◽  
Excellent Source ◽  
Reduction Capacity

Plant-derived protein hydrolysates have potential applications in nutrition. Rice protein hydrolysates (RPHs), an excellent source of proteins, have attracted attention for the development of cosmeceuticals. However, few studies have reported the potential application of RPH in analysis, and this study examined their antioxidant activities and the inhibitory activities of skin aging enzymes. The results indicated that the total phenolic and flavonoid concentrations were 2.06 ± 0.13 mg gallic acid equivalent/g RPHs and 25.96 ± 0.52 µg quercetin equivalent/g RPHs, respectively. RPHs demonstrated dose-dependent activity for scavenging free radicals from 1,1-diphenyl-2-picrylhydrazyl [half-maximal inhibitory concentration (IC50) = 42.58 ± 2.1 mg/g RPHs] and 2,2′-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (IC50 = 2.11 ± 0.88 mg/g RPHs), dose-dependent reduction capacity (6.95 ± 1.40 mg vitamin C equivalent/g RPHs) and oxygen radical absorbance capacity (473 µmol Trolox equivalent/g RPHs). The concentrations of the RPH solution required to achieve 50% inhibition of hyaluronidase and tyrosinase activities were determined to be 8.91 and 107.6 mg/mL, respectively. This study demonstrated that RPHs have antioxidant, antihyaluronidase, and antityrosinase activities for future cosmetic applications.

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