Aqueous extract of berry (Plinia jaboticaba)byproduct modulates gut microbiota and maintains the balance on antioxidant defense system in rats

2018 ◽  
Vol 43 (2) ◽  
pp. e12705 ◽  
Author(s):  
Juliana Kelly da Silva-Maia ◽  
Angela Giovana Batista ◽  
Luiz Claudio Correa ◽  
Glaucia Carielo Lima ◽  
Stanislau Bogusz Junior ◽  
...  
Keyword(s):  
Gut Microbiota ◽  
Aqueous Extract ◽  
Antioxidant Defense ◽  
Antioxidant Defense System ◽  
Defense System

Oligopeptides from Jinhua ham prevent alcohol-induced liver damage by regulating intestinal homeostasis and oxidative stress in mice

2021 ◽  
Author(s):  
Wen Nie ◽  
Ye-ye Du ◽  
Fei-ran Xu ◽  
Kai Zhou ◽  
Zhao-ming Wang ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Gut Microbiota ◽  
Liver Damage ◽  
Antioxidant Defense ◽  
Antioxidant Defense System ◽  
Bioactive Peptide ◽  
Defense System ◽  
Stress Injury ◽  
Jinhua Ham ◽  
And Oxidative Stress

Lys-Arg-Gln-Lys-Tyr-Asp bioactive peptide in JHP prevent ALD by regulating gut microbiota, upregulating the expression of the NRF2/HO-1 antioxidant defense system and reducing oxidative stress injury in liver cells.

scholarly journals Thymus vulgaris extract modulates dexamethasone induced liver injury and restores the hepatic antioxidant redox system

2019 ◽  
Vol 8 (1) ◽  
Author(s):  
Howida Sayed Abou-Seif ◽  
Walaa Gamal Hozayen ◽  
Khalid Shaaban Hashem
Keyword(s):  
Oxidative Stress ◽  
Liver Function ◽  
Aqueous Extract ◽  
Antioxidant Defense ◽  
Natural Antioxidants ◽  
Antioxidant Defense System ◽  
Thymus Vulgaris ◽  
High Dose ◽  
Toxic Substances ◽  
Defense System

Abstract Background The liver is the largest important organ and the site for essential biochemical reactions and detoxifying toxic substances in the human body. Long-term, high-dose dexamethasone administration can cause severe alterations in liver function. Therefore, Thymus vulgaris leave extract possess a modulatory role on dexamethasone-induced hepatotoxicity by attenuating antioxidant defense system. By subcutaneous route, animals will receive three doses per week for 8 weeks of dexamethasone (0.1 mg/kg. b. wt.) concomitant with oral administration of thyme aqueous extract (500 mg/kg b.wt.). Results DXM treatment led to a marked increase in the liver function enzyme activities that are successfully ameliorated by thyme aqueous extract. Thyme natural antioxidants augmented the antioxidant defense system that overcomes oxidative stress caused by dexamethasone. Conversely, although dexamethasone-treated animals rose lipid peroxidation, thyme extract pretreatment did the reverse. Conclusion Hepatotoxicity and oxidative stress caused by dexamethasone might improve by thyme natural antioxidants.

scholarly journals Anti-inflammatory activity of a water-soluble polysaccharide from the roots of purple sweet potato

RSC Advances ◽  
2020 ◽  
Vol 10 (65) ◽  
pp. 39673-39686
Author(s):  
Jian Sun ◽  
Yarun Gou ◽  
Jun Liu ◽  
Hong Chen ◽  
Juan Kan ◽  
...  
Keyword(s):  
Gut Microbiota ◽  
Sweet Potato ◽  
Antioxidant Defense ◽  
Antioxidant Defense System ◽  
Water Soluble ◽  
Defense System ◽  
System P ◽  
Soluble Polysaccharide ◽  
Anti Inflammatory ◽  
Purple Sweet Potato

A water-soluble polysaccharide from purple sweet potato roots played anti-inflammatory roles by regulating inflammatory cytokines, gut microbiota and antioxidant defense system.

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