scholarly journals Spatially varying selection shapes life history clines among populations of Drosophila melanogaster from sub-Saharan Africa

2015 ◽  
Vol 28 (4) ◽  
pp. 826-840 ◽  
Author(s):  
D. K. Fabian ◽  
J. B. Lack ◽  
V. Mathur ◽  
C. Schlötterer ◽  
P. S. Schmidt ◽  
...  
Keyword(s):  
Drosophila Melanogaster ◽  
Life History ◽  
Sub Saharan Africa ◽  
Sub Saharan ◽  
Spatially Varying ◽  
Spatially Varying Selection

scholarly journals Recurrent Collection of Drosophila melanogaster from Wild African Environments and Genomic Insights into Species History

2019 ◽  
Vol 37 (3) ◽  
pp. 627-638 ◽  
Author(s):  
Quentin D Sprengelmeyer ◽  
Suzan Mansourian ◽  
Jeremy D Lange ◽  
Daniel R Matute ◽  
Brandon S Cooper ◽  
...  
Keyword(s):  
Drosophila Melanogaster ◽  
Demographic History ◽  
Central Africa ◽  
Model Organism ◽  
Sub Saharan Africa ◽  
Wilderness Areas ◽  
Southern Central ◽  
History Of ◽  
Sub Saharan ◽  
Improved Model

Abstract A long-standing enigma concerns the geographic and ecological origins of the intensively studied vinegar fly, Drosophila melanogaster. This globally distributed human commensal is thought to originate from sub-Saharan Africa, yet until recently, it had never been reported from undisturbed wilderness environments that could reflect its precommensal niche. Here, we document the collection of 288 D. melanogaster individuals from multiple African wilderness areas in Zambia, Zimbabwe, and Namibia. The presence of D. melanogaster in these remote woodland environments is consistent with an ancestral range in southern-central Africa, as opposed to equatorial regions. After sequencing the genomes of 17 wilderness-collected flies collected from Kafue National Park in Zambia, we found reduced genetic diversity relative to town populations, elevated chromosomal inversion frequencies, and strong differences at specific genes including known insecticide targets. Combining these genomes with existing data, we probed the history of this species’ geographic expansion. Demographic estimates indicated that expansion from southern-central Africa began ∼13,000 years ago, with a Saharan crossing soon after, but expansion from the Middle East into Europe did not begin until roughly 1,800 years ago. This improved model of demographic history will provide an important resource for future evolutionary and genomic studies of this key model organism. Our findings add context to the history of D. melanogaster, while opening the door for future studies on the biological basis of adaptation to human environments.

scholarly journals Life History of the Golden Puddle Frog, Phrynobatrachus auritus Boulenger 1900 (Anura: Phrynobatrachidae)

2016 ◽  
Vol 8 (3) ◽  
pp. 77
Author(s):  
Geraud Canis Tasse Taboue ◽  
Eric Bertrand Fokam
Keyword(s):  
Life History ◽  
Development Time ◽  
Captive Breeding ◽  
Sub Saharan Africa ◽  
Advertisement Call ◽  
Calling Behaviour ◽  
Number Of Factors ◽  
History Of ◽  
Sub Saharan

Frogs of the genus <em>Phrynobatrachus </em>Günther, 1862 are endemic to sub-Saharan Africa. These are increasingly threatened by a number of factors and are believed to be declining. We report on captive breeding experiments involving <em>Phrynobatrachus auritus</em> Boulenger, 1900. We provide a comprehensive life history for this frog with emphasize on tadpole development time, as well as a description of both the advertisement call and calling behaviour of the adult.

Oligogenic Adaptation, Soft Sweeps, and Parallel Melanic Evolution in Drosophila melanogaster

2016 ◽  
Author(s):  
Héloïse Bastide ◽  
Jeremy D. Lange ◽  
Justin B. Lack ◽  
Yassin Amir ◽  
John E. Pool
Keyword(s):  
Drosophila Melanogaster ◽  
Genetic Variation ◽  
Evolutionary Biology ◽  
Genetic Architecture ◽  
Genetic Basis ◽  
Simulation Analysis ◽  
Mapping Method ◽  
Sub Saharan Africa ◽  
Mountain Ranges ◽  
Sub Saharan

AbstractUnraveling the genetic architecture of adaptive phenotypic divergence is a fundamental quest in evolutionary biology. In Drosophila melanogaster, high-altitude melanism has evolved in separate mountain ranges in sub-Saharan Africa, potentially as an adaptation to UV intensity. We investigated the genetic basis of this melanism in three populations using a new bulk segregant analysis mapping method. Although hundreds of genes are known to affect cuticular pigmentation in D. melanogaster, we identified only 19 distinct QTLs from 9 mapping crosses, with several QTL peaks being shared among two or all populations. Surprisingly, we did not find wide signals of genetic differentiation (Fst) between lightly and darkly pigmented populations at these QTLs, in spite of the pronounced phenotypic difference in pigmentation. Instead, we found small numbers of highly differentiated SNPs at the probable causative genes. A simulation analysis showed that these patterns of polymorphism are consistent with selection on standing genetic variation (leading to “soft sweeps“). Our results thus support a role for oligogenic selection on standing genetic variation in driving parallel ecological adaptation.

Determinants of genetic structure of the Sub-Saharan parasitic wasp Cotesia sesamiae

2017 ◽  
Author(s):  
Antoine Branca ◽  
Bruno Le Ru ◽  
Paul-André Calatayud ◽  
Julius Obonyo ◽  
Boaz Muzyoka ◽  
...  
Keyword(s):  
Biological Control ◽  
Life History ◽  
Genetic Structure ◽  
Parasitic Wasp ◽  
Sub Saharan Africa ◽  
Host Specialization ◽  
Life History Strategies ◽  
Cotesia Sesamiae ◽  
Sub Saharan ◽  
Different Strains

AbstractParasitoid life style represents one of the most diversified life history strategies on earth. There are however very few studies on the variables associated with intraspecific diversity of parasitoid insects, especially regarding the relationship with spatial, biotic and abiotic ecological factors. Cotesia sesamiae is a Sub-Saharan stenophagous parasitic wasp that parasitizes several African stemborer species with variable developmental success. The different host-specialized populations are infected with different strains of Wolbachia, an endosymbiotic bacterium widespread in arthropods that is known for impacting life history traits notably reproduction, and consequently species distribution. In this study, first we analyzed the genetic structure of C. sesamiae across Sub-Saharan Africa, using 8 microsatellite markers, and 3 clustering software. We identified five major population clusters across Sub-Saharan Africa, which probably originated in East African Rift region and expanded throughout Africa in relation to host genus and abiotic factors such as climatic classifications. Using laboratory lines, we estimated the incompatibility between the different strains of Wolbachia infecting C. sesamiae. We observed an incompatibility between Wolbachia strains was asymmetric; expressed in one direction only. Based on these results, we assessed the relationships between direction of gene flow and Wolbachia infections in the genetic clusters. We found that Wolbachia-induced reproductive incompatibility was less influential than host specialization in the genetic structure. Both Wolbachia and host were more influential than geography and current climatic conditions. These results are discussed in the context of African biogeography, and co-evolution between Wolbachia, virus parasitoid and host, in the perspective of improving biological control efficiency through a better knowledge of the biodiversity of biological control agents.

scholarly journals Adaptive divergence of a transcriptional enhancer between populations of Drosophila melanogaster

2013 ◽  
Vol 368 (1632) ◽  
pp. 20130024 ◽  
Author(s):  
Amanda Glaser-Schmitt ◽  
Ana Catalán ◽  
John Parsch
Keyword(s):  
Drosophila Melanogaster ◽  
Local Environment ◽  
European Population ◽  
Sub Saharan Africa ◽  
Adaptive Divergence ◽  
Transcriptional Enhancer ◽  
Enhancer Activity ◽  
Expression Difference ◽  
The Difference ◽  
Sub Saharan

As species colonize new habitats they must adapt to the local environment. Much of this adaptation is thought to occur at the regulatory level; however, the relationships among genetic polymorphism, expression variation and adaptation are poorly understood. Drosophila melanogaster , which expanded from an ancestral range in sub-Saharan Africa around 15 000 years ago, represents an excellent model system for studying regulatory evolution. Here, we focus on the gene CG9509 , which differs in expression between an African and a European population of D. melanogaster . The expression difference is caused by variation within a transcriptional enhancer adjacent to the CG9509 coding sequence. Patterns of sequence variation indicate that this enhancer was the target of recent positive selection, suggesting that the expression difference is adaptive. Analysis of the CG9509 enhancer in new population samples from Europe, Asia, northern Africa and sub-Saharan Africa revealed that sequence polymorphism is greatly reduced outside the ancestral range. A derived haplotype absent in sub-Saharan Africa is at high frequency in all other populations. These observations are consistent with a selective sweep accompanying the range expansion of the species. The new data help identify the sequence changes responsible for the difference in enhancer activity.

scholarly journals Genome-wide patterns of local adaptation in Drosophila melanogaster: adding intra European variability to the map

2018 ◽  
Author(s):  
Lidia Mateo ◽  
Gabriel E. Rech ◽  
Josefa González
Keyword(s):  
Drosophila Melanogaster ◽  
Population Structure ◽  
Local Adaptation ◽  
Population Differentiation ◽  
Nucleotide Polymorphisms ◽  
Low Levels ◽  
Spatially Varying ◽  
Spatially Varying Selection ◽  
Two Populations ◽  
European Populations

ABSTRACTSignatures of spatially varying selection have been investigated both at the genomic and transcriptomic level in several organisms. In Drosophila melanogaster, the majority of these studies have analyzed North American and Australian populations, leading to the identification of several loci and traits under selection. However, populations in these two continents showed evidence of admixture that likely contributed to the observed population differentiation patterns. Thus, disentangling demography from selection is challenging when analyzing these populations. European populations could be a suitable system to identify loci under spatially varying selection provided that no recent admixture from African populations would have occurred. In this work, we individually sequence the genome of 42 European strains collected in populations from contrasting environments: Stockholm (Sweden), and Castellana Grotte, (Southern Italy). We found low levels of population structure and no evidence of recent African admixture in these two populations. We thus look for patterns of spatially varying selection affecting individual genes and gene sets. Besides single nucleotide polymorphisms, we also investigate the role of transposable elements in local adaptation. We concluded that European populations are a good dataset to identify loci under spatially varying selection. The analysis of the two populations sequenced in this work in the context of all the available D. melanogaster data allowed us to pinpoint genes and biological processes relevant for local adaptation. Identifying and analyzing populations with low levels of population structure and admixture should help to disentangle selective from non-selective forces underlying patterns of population differentiation in other species as well.

scholarly journals Functional Analysis of a Putative Target of Spatially Varying Selection in the Menin1 Gene of Drosophila melanogaster

2018 ◽  
Vol 9 (1) ◽  
pp. 73-80 ◽  
Author(s):  
Nicolas Svetec ◽  
Perot Saelao ◽  
Julie M. Cridland ◽  
Ary A. Hoffmann ◽  
David J. Begun
Keyword(s):  
Functional Analysis ◽  
Drosophila Melanogaster ◽  
Putative Target ◽  
Spatially Varying ◽  
Spatially Varying Selection

scholarly journals Ancient hybridization and introgression of an invadolysin gene in schistosome parasites

2019 ◽  
Author(s):  
Roy N. Platt ◽  
Marina McDew-White ◽  
Winka Le Clec’h ◽  
Frederic D. Chevalier ◽  
Fiona Allan ◽  
...  
Keyword(s):  
Life History ◽  
Schistosoma Haematobium ◽  
Life History Traits ◽  
Single Gene ◽  
Sub Saharan Africa ◽  
Urogenital Schistosomiasis ◽  
Introgression Event ◽  
Sub Saharan ◽  
Hybridization And Introgression ◽  
Ancient Hybridization

The parasitic blood fluke Schistosoma haematobium causes urogenital schistosomiasis in humans and is a major cause of morbidity and mortality across sub-Saharan Africa. S. haematobium hybridizes with livestock schistosomes, including S. bovis, however the frequency, direction, age and genomic consequences of hybridization are unknown. We sequenced 96 S. haematobium exomes from Niger and the Zanzibar archipelago. and found evidence of an ancient, introgression event between Nigerien S. haematobium and S. bovis occurring 108-613 generations ago. Between 3.3-8.2% of Nigerien S. haematobium genomes are derived from S. bovis alleles, some of which show signatures of directional selection; the strongest signal spans a single gene in the invadolysin gene family, an M8 metalloprotease associated with parasitic life-history traits.

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