scholarly journals Ageing research: rethinking primary prevention of skin cancer

2021 ◽  
Vol 35 (11) ◽  
pp. 2216-2218
Author(s):  
C. Posch
Keyword(s):  
Primary Prevention ◽  
Skin Cancer ◽  
Ageing Research

Skin cancer prevention: a link between primary prevention and early detection?

2010 ◽  
Vol 18 (4) ◽  
pp. 417-420 ◽  
Author(s):  
Peter J. Anderson ◽  
John B. Lowe ◽  
Warren R. Stanton ◽  
Kevin P. Balanda
Keyword(s):  
Primary Prevention ◽  
Skin Cancer ◽  
Early Detection ◽  
Cancer Prevention ◽  
Skin Cancer Prevention ◽  
Prevention And Early Detection

Primary Prevention of Skin Cancer

2014 ◽  
pp. 223-230
Author(s):  
Monika Janda ◽  
Adèle C. Green
Keyword(s):  
Primary Prevention ◽  
Skin Cancer

A randomized trial of selenium and vitamin E for primary prevention of non-melanoma skin cancer: Trial results and experience from a low-resource setting.

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. 1511-1511 ◽  
Author(s):  
Maria Argos ◽  
James J. Dignam ◽  
Faruque Parvez ◽  
Mahfuzar Rahman ◽  
Samar K Hore ◽  
...  
Keyword(s):  
Vitamin E ◽  
Primary Prevention ◽  
Skin Cancer ◽  
Beneficial Effect ◽  
Population Based ◽  
Cancer Trial ◽  
Low Resource ◽  
Non Melanoma Skin Cancer ◽  
Related Mortality ◽  
Melanoma Skin

1511 Background: Selenium and vitamin E supplementation previously have shown some evidence of a beneficial effect in the secondary prevention of non-melanoma skin cancer (NMSC). More than 100 million people worldwide are at increased risk of NMSC and other cancers due to arsenic exposure from drinking water and diet – a risk that persists for several decades even after the exposure has terminated. Here, we report on the design, methods and main results of the Bangladesh Vitamin E and Selenium Trial (BEST) – a population-based chemoprevention study conducted among 7,000 adults with visible arsenic toxicity. Methods: BEST is a 2 × 2 full factorial, double-blind, randomized placebo controlled trial of 7,000 adults having manifest arsenical skin lesions evaluating the efficacy of 6-year supplementation with alpha-tocopherol (100 mg daily) and L-selenomethionine (200 μg daily) for the prevention of NMSC incidence. Results: Excellent compliance was maintained through the course of the trial, based on data from pill counts, self-reported compliance, and bioadherence. Among participants on treatment through the end of the 6-year intervention period, > 85% were adherent to at least 80% of study supplements. More than 500 new NMSC cases were ascertained using a three-tiered biopsy protocol. No significant beneficial effects were observed on NMSC incidence during the study period for selenium or vitamin E. Among more than 500 observed deaths (including 182 cancer-related deaths), there were also no significant treatment effects on total mortality, cancer-related mortality or arsenical cancer-related mortality. Conclusions: This large population-based trial does not support any beneficial effect of vitamin E or selenium supplementation for the primary prevention of NMSC or mortality in an arsenic-exposed population. With the rapidly increasing burden of preventable cancers in low- and middle-income countries, efficient and feasible chemoprevention study designs and approaches, such as employed in Bangladesh, may prove impactful in conceiving large scale cancer chemoprevention trials in low-resource settings. Clinical trial information: NCT00392561.

Generating political priority for skin cancer primary prevention: A case study from Aotearoa New Zealand

2021 ◽  
Author(s):  
Ryan Gage ◽  
William Leung ◽  
Marcus Gurtner ◽  
Anthony I. Reeder ◽  
Bronwen M. McNoe ◽  
...  
Keyword(s):  
New Zealand ◽  
Primary Prevention ◽  
Skin Cancer ◽  
Aotearoa New Zealand ◽  
Political Priority

Promoting Sun Protection in Children: Rationale and Challenges

1999 ◽  
Vol 26 (3) ◽  
pp. 409-417 ◽  
Author(s):  
David Hill ◽  
Helen Dixon
Keyword(s):  
Cost Effectiveness ◽  
Primary Prevention ◽  
Skin Cancer ◽  
Sun Protection ◽  
Skin Cancer Prevention ◽  
Special Issue ◽  
Behavioral Outcome ◽  
Behavioral Studies ◽  
The Cost ◽  
And Behavior

This article outlines the epidemiological and educational arguments for promoting sun protection during childhood and highlights factors that may facilitate or hinder achievement of this behavioral outcome. A model describing behavioral factors in the causation of skin cancer is presented. Summary results from previous behavioral studies and interventions relating to primary prevention of skin cancer are described, and recent data on the cost-effectiveness of sun protection in Australia and its implications for health insurers are discussed. This article also includes a commentary on the demonstration projects promoting skin cancer prevention among children and their caregivers featured in this special issue of Health Education and Behavior.

Sign in / Sign up

Export Citation Format

Share Document