Decreased melanocyte counts in the upper hair follicle in frontal fibrosing alopecia compared to lichen planopilaris: a retrospective histopathologic study

2020 ◽  
Author(s):  
A.C. Katoulis ◽  
K. Diamanti ◽  
V. Damaskou ◽  
A. Pouliakis ◽  
E. Bozi ◽  
...  
Keyword(s):  
Hair Follicle ◽  
Lichen Planopilaris ◽  
Histopathologic Study

Lichen Planopilaris-Like Changes Arising within an Epidermal Nevus: Does This Case Suggest Clues to the Etiology of Lichen Planopilaris?

2000 ◽  
Vol 4 (1) ◽  
pp. 30-35 ◽  
Author(s):  
Kathleen J. Smith ◽  
Jacob Crittenden ◽  
Henry Skelton
Keyword(s):  
Hair Follicle ◽  
Hair Loss ◽  
Black Male ◽  
Central Area ◽  
Lymphocytic Infiltrate ◽  
Epidermal Nevus ◽  
Lichen Planopilaris ◽  
The Past ◽  
History Of ◽  
Initiating Factors

Background: Lichen planopilaris shows a perifollicular lymphocytic infiltrate at the level of infundibulum and the isthmus of the hair bulge resulting in necrotic changes within keratinocytes and eventually hair loss. Objective: We present a 14-year-old black male with a history of a raised epidermal lesion on the scalp that was present at birth. Over the past few years, the patient developed gradual hair loss and increased verrucous changes of the skin within the original lesion. Histologic sections of the area showed features consistent with an epidermal nevus peripherally, with a central area showing some features characteristic of those seen in lichen planopilaris. In addition, there was marked hyperkeratosis with increased yeast and bacteria within the follicles. Conclusions: Initiating factors in lichen planopilaris are not well defined. Overgrowth of microorganisms with hyperkeratosis results in factors that disrupt the immune privilege of the hair follicle, leading to an immunologic reaction that is limited to the follicle and spares surrounding eccrine structures. This case suggests possible mechanisms involved in the induction of lichen planopilaris.

scholarly journals Does mitochondrial dysfunction of hair follicle epithelial stem cells play a role in the pathobiology of lichen planopilaris?

2020 ◽  
Vol 183 (5) ◽  
pp. 964-966
Author(s):  
J.A. Hardman‐Smart ◽  
T.S. Purba ◽  
S. Panicker ◽  
B. Farjo ◽  
N. Farjo ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mitochondrial Dysfunction ◽  
Hair Follicle ◽  
Epithelial Stem Cells ◽  
Lichen Planopilaris

A method for culturing human hair follicle cells. (II). Plucked human hair follicles.

1988 ◽  
Vol 50 (2) ◽  
pp. 271-276 ◽  
Author(s):  
Ryuichiro KUWANA ◽  
Seiji ARASE ◽  
Yasushi SADAMOTO ◽  
Hideki NAKANISHI ◽  
Katsuyuki TAKEDA
Keyword(s):  
Hair Follicle ◽  
Human Hair ◽  
Hair Follicles ◽  
Follicle Cells ◽  
Human Hair Follicle
Sign in / Sign up

Export Citation Format

Share Document