scholarly journals Complete clearance and psoriasis area and severity index response for brodalumab and ustekinumab in AMAGINE‐2 and ‐3

2020 ◽  
Author(s):  
R.B. Warren ◽  
J.B. Hansen ◽  
K. Reich ◽  
C. Paul ◽  
L. Puig
Keyword(s):  
Severity Index ◽  
Complete Clearance

Teen Addiction Severity Index

1991 ◽  
Author(s):  
Yifrah Kaminer ◽  
Oscar Bukstein ◽  
Ralph E. Tarter
Keyword(s):  
Severity Index ◽  
Addiction Severity Index ◽  
Addiction Severity

ANALISIS RISIKO PELAKSANAAN PROYEK PEMBANGUNAN PRASARANA PENGENDALI BANJIR TUKAD SUNGI YANG BERPENGARUH TERHADAP KINERJA BIAYA DAN WAKTU

2020 ◽  
Vol 8 (2) ◽  
pp. 77-88
Author(s):  
Ni Putu Indah Yuliana ◽  
Ni Made Sintya Rani
Keyword(s):  
Severity Index

Proyek pembangunan prasarana pengendali banjir Tukad Sungi memiliki risiko yang cukup tinggi. Tujuan penelitian untuk mengidentifikasi, menilai dan memberikan respons terhadap risiko yang berpengaruh terhadap kinerja biaya dan waktu proyek. Penelitian dilakukan dengan metode penelitian campuran antara metode deskriptif kuantitatif dengan deskriptif kualitatif. Pengumpulan data dengan wawancara dan analisis data dengan Severity Index (SI). Hasil penelitian menunjukkan risiko yang teridentifikasi sebanyak 25 (dua puluh lima) risiko yang bersumber dari 8 (delapan) sumber risiko. Risiko yang memiliki nilai ekstrim dan berpengaruh terhadap kinerja biaya adalah adanya addendum saat pelaksanaan pekerjaan, cuaca yang berubah-ubah atau tidak menentu sehingga menghambat pekerjaan dan adanya penyesuaian dengan kondisi lapangan sehingga terjadi perubahan desain pekerjaan. Risiko yang memiliki nilai ekstrim dan berpengaruh terhadap kinerja waktu adalah adanya kekurangan pada pendanaan untuk melaksanakan pekerjaan dan adanya kesalahan dalam pengukuran lapangan untuk menentukan titik pekerjaan sehingga tidak sesuai gambar. Respon terhadap risiko diantaranya penyedia jasa menyediakan dana awal, melaksanakan addendum dengan segera, memakai data ramalan cuaca dari pihak BMKG, melakukan pengukuran ulang dan melakukan perubahan dengan segera dan meminta persetujuan pemilik pekerjaan. 

Evaluation of anti-psoriatic activity of selected phytochemicals on UV-induced psoriasis in mouse tail model

2020 ◽  
Vol 64 ◽  
pp. 123-128
Author(s):  
Jada Naga Lakshmi ◽  
A. Narendra Babu ◽  
Rama Rao Nadendla
Keyword(s):  
Disease Control ◽  
Ellagic Acid ◽  
Uv Light ◽  
Severity Index ◽  
Treated Group ◽  
Control Group ◽  
Standard Group ◽  
Significant Activity ◽  
Epidermal Thickness ◽  
Psoriasis Severity

Objectives: To evaluate anti-psoriatic activity of Phytochemicals on UV-Induced psoriasis in mouse tail model. Materials and Methods: Anti-psoriatic activity of selected phytochemicals on UV-Induced psoriasis in mouse tail model. The animals were dividing into 05 groups and each group contain 5 animals. Disease control group did not receive any treatment only exposure to UV-light, vehicle control treated with simple ointment, standard group treated with salicylic acid (1%w/w) ointment, remaining group are treated 1% and 2% selective phytochemical at two concentrations of ointment to topically on the tail skin. And the data were analysed using one way ANOVA followed by two-way ANOVA (Dunnett’s multiple comparisons test). Results: There was significant decrease in epidermal thickness (P < 0.05) as compared with control group. In 2% phytoconstituents has shown a significant reduction in the total epidermal thickness 8.4****±0.748, 7.6**±0.6781 and 8*±0.8366 in geraniol, glycyrrhizic acid and ellagic acid treated group, when compare to the disease induced animal, there was no lesion of Munro’s microabscess, capillary loop dilation along with elongation of rete ridges in the section of skin of rats. Psoriasis Severity Index was reduced in test treated groups as compared with that of disease control group. It was slowly reduced to 2nd week, totally (55-70%) reduction in PSI is observed at the time of third week of treatment period. Conclusion: The result of the study showed that the 2% of geraniol, ellagic acid, glycyrrhizicacid and hesperidin, exhibited significant activity on UV-induced psoriasis in rodents. The study implies that selected phytoconstituents are a promising research for further investigations to prove its anti-psoriatic activity.

Modified CT severity index for evaluation of acute pancreatitis and correlation with patient outcome

2020 ◽  
Vol 13 (3) ◽  
pp. 154-161
Author(s):  
Polysetty Obuleswar Prasad ◽  
◽  
N S Vidya ◽  
G V. Prasad ◽  
D R Anand ◽  
...  
Keyword(s):  
Patient Outcome ◽  
Acute Pancreatitis ◽  
Severity Index

Clinical Profile and Outcomes in Patients with Acute Pancreatitis attending a Teaching Hospital at Gandaki Province, Nepal

2020 ◽  
Vol 16 (3) ◽  
Author(s):  
Subash Bhattarai ◽  
Merina Gyawali
Keyword(s):  
Acute Pancreatitis ◽  
Severe Acute Pancreatitis ◽  
Age Groups ◽  
Data Entry ◽  
Kidney Injury ◽  
Severity Index ◽  
Clinical Profile ◽  
Cross Sectional ◽  
Systemic Complications ◽  
Keywords Alcohol

Background: Acute pancreatitis (AP) is inflammatory process of pancreas presenting with acute abdominal pain.The majority of patients have mild disease. Some patients develop local and systemic complications with increased morbidity and mortality. This study was undertaken to describe the clinical profile and outcomes in patients with acute pancreatitis.   Methods:  A cross-sectional hospital based study comprising of 62 consecutive patients with acute pancreatitis were enrolled between Jan 2019 to August 2020. Clinical profile at admission, complications and clinical outcomes including mortality were studied. Patients were classified into mild, moderately severe and severe acute pancreatitis based on revised Atlanta classification and modified CT severity index.  Data entry was done in Statistical Packages for the Social Sciences version 20. Results: The mean age of study subjects was 44±10.87 years with 43 (56%) males and 19 (44%) females (M:F=2.1:1). The commonest etiology of pancreatitis was alcohol (53.2%) followed by biliary pancreatitis (37.1%)  The most common presentation was abdominal pain (100%). The most common complication was pancreatic necrosis (21%) followed by acute kidney injury (19.4%) and pleural effusion (17.3%). Majority( 72.6%) was mild and 17.7% had severe acute pancreatitis. Mortality was seen in 6.5% patients. Mortality was observed in patients with persistent complications, organ failure, low serum calcium and high modified CT severity index.   Conclusions: Alcohol and gallstones were the two main etiologies of acute pancreatitis and were common in males, and in middle age groups. Majority presented with mild severity. Mortality was observed in some patients with severe acute pancreatitis.   Keywords: alcohol; biliary; CT severity index; mortality; outcome; pancreatitis          

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