Mycoplasma pneumoniae ‐associated Stevens–Johnson syndrome: characteristic histological features of mucosal lesion

2020 ◽  
Author(s):  
T. Katsumi ◽  
N. Hama ◽  
Y. Iwai ◽  
K. Kimura ◽  
O. Ansai ◽  
...  
Keyword(s):  
Mycoplasma Pneumoniae ◽  
Mucosal Lesion ◽  
Stevens Johnson Syndrome ◽  
Histological Features ◽  
Johnson Syndrome

scholarly journals Mycoplasma pneumoniae-induced rash and mucositis: A new entity

2021 ◽  
Vol 0 ◽  
pp. 1-5
Author(s):  
Mohamed Ben Rejeb ◽  
Mouna Ben Hammouda ◽  
Mouna Korbi ◽  
Hichem Belhadjali ◽  
Adnene Toumi ◽  
...  
Keyword(s):  
Mycoplasma Pneumoniae ◽  
Erythema Multiforme ◽  
Community Acquired Pneumonia ◽  
Stevens Johnson Syndrome ◽  
Cutaneous Lesions ◽  
Drug Induced ◽  
Histological Features ◽  
Johnson Syndrome ◽  
Mucosal Involvement ◽  
Epidermal Necrosis

Mycoplasma pneumoniae is a well-known cause of community-acquired pneumonia, mostly associated with dermatological manifestations especially with mucosal involvement and targetoid cutaneous lesions. For many years, it was considered among the spectrum of erythema multiforme. Recently, some authors have recommended the creation of a new syndrome called “mycoplasma-induced rash and mucositis.” This new syndrome has distinct epidemiological, clinical and histological features making it different from drug-induced Stevens-Johnson syndrome, toxic epidermal necrosis and erythema multiforme. Herein, we report two patients with acute Mycoplasma pneumoniae respiratory tract infection presenting severe mucocutaneous lesions in accordance with this new syndrome.

scholarly journals 504 Mycoplasma pneumoniae-associated Stevens-Johnson syndrome; clinical and histological features

2017 ◽  
Vol 137 (10) ◽  
pp. S278
Author(s):  
T. Katsumi ◽  
N. Hama ◽  
Y. Iwai ◽  
K. Kimura ◽  
T. Suzuki ◽  
...  
Keyword(s):  
Mycoplasma Pneumoniae ◽  
Stevens Johnson Syndrome ◽  
Histological Features ◽  
Johnson Syndrome

Rash and Mucositis Associated With Mycoplasma pneumoniae and Chlamydophila pneumoniae: A Recurrence of MIRM?

2020 ◽  
Author(s):  
Danielle Brazel ◽  
Brooke Kulp ◽  
Geoanna Bautista ◽  
Andrew Bonwit
Keyword(s):  
Mycoplasma Pneumoniae ◽  
Treatment Options ◽  
Specific Treatment ◽  
Corticosteroid Treatment ◽  
Stevens Johnson Syndrome ◽  
First Case ◽  
Johnson Syndrome ◽  
Vesicular Rash ◽  
Recurrent Aphthous Ulcers ◽  
Definition Of

Abstract Introduction A new concept has come to light recently, that is, Mycoplasma-induced rash and mucositis (MIRM). Here, we report the first case of recurrent rash, mucositis, and conjunctivitis involving Mycoplasma pneumoniae and C. pneumoniae that fits under the criteria of what is currently defined as MIRM. Case Presentation A patient aged 12 years with a history of recurrent aphthous ulcers presented in 2013 with worsening oral lesions, conjunctivitis, and vesicular rash. Her respiratory polymerase chain reaction (PCR) panel was positive for M. pneumoniae. She was diagnosed with Stevens-Johnson syndrome (SJS) secondary to M. pneumoniae and treated with a macrolide, acyclovir, and intravenous immunoglobulin (IVIG). The same patient returned 3 years later with an identical constellation of symptoms, at which time her PCR was positive for C. pneumoniae. In addition to IVIG and a macrolide, a corticosteroid treatment was administered. Discussion Here, we present the case of a pediatric patient with a recurrence of mucocutaneous disease that is more consistent with MIRM than the proposed SJS or erythema multiforme (EM) documented via histology. Our patient’s symptoms were controlled with azithromycin and IVIG and, in the second episode, with corticosteroids as well. This case adds to that of Mayor-Ibarguren et al, providing further evidence that C. pneumonia may also be a trigger for MIRM. Patients will benefit from expanding the definition of MIRM, as the pathogenesis differs from SJS and EM and could result in more specific treatment options.

Mycoplasma pneumoniae‑induced pneumonia with Stevens‑Johnson syndrome of acute atypical course

2008 ◽  
Vol 118 (7-8) ◽  
pp. 449-453
Author(s):  
Magdalena Walicka ◽  
Magdalena Majsterek ◽  
Adriana Rakowska ◽  
Monika Słowińska ◽  
Justyna Sicińska ◽  
...  
Keyword(s):  
Mycoplasma Pneumoniae ◽  
Stevens Johnson Syndrome ◽  
Johnson Syndrome

Stevens-Johnson Syndrome in a Boy With Macrolide-Resistant Mycoplasma pneumoniae Pneumonia

PEDIATRICS ◽  
2011 ◽  
Vol 127 (6) ◽  
pp. e1605-e1609 ◽  
Author(s):  
T. P. Atkinson ◽  
S. Boppana ◽  
A. Theos ◽  
L. S. Clements ◽  
L. Xiao ◽  
...  
Keyword(s):  
Mycoplasma Pneumoniae ◽  
Stevens Johnson Syndrome ◽  
Johnson Syndrome ◽  
Mycoplasma Pneumoniae Pneumonia

Mycoplasma pneumoniae and Stevens-Johnson Syndrome

2017 ◽  
Vol 25 (1) ◽  
pp. 43-47
Author(s):  
Nelly Álvarez Álvarez ◽  
Sheila Fernández-Luis ◽  
Claudia Sánchez-Villares Lorenzo ◽  
Mónica Lilian Roncero Toscano ◽  
María del Carmen Mendoza Sánchez
Keyword(s):  
Mycoplasma Pneumoniae ◽  
Stevens Johnson Syndrome ◽  
Johnson Syndrome

Stevens-Johnson syndrome due to mycoplasma pneumoniae in an adult

1985 ◽  
Vol 79 (4) ◽  
pp. 541-544 ◽  
Author(s):  
Robert E. Kalb ◽  
Marc E. Grossman ◽  
Harold C. Neu
Keyword(s):  
Mycoplasma Pneumoniae ◽  
Stevens Johnson Syndrome ◽  
Johnson Syndrome
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