Expression of PD‐1 and Tim‐3 is increased in skin of patients with bullous pemphigoid and pemphigus vulgaris

2020 ◽  
Author(s):  
N. Ernst ◽  
M. Friedrich ◽  
K. Bieber ◽  
M. Kasperkiewicz ◽  
N. Gross ◽  
...  
Keyword(s):  
Bullous Pemphigoid ◽  
Pemphigus Vulgaris

Statistical Study of Patients with pemphigus Vulgaris and Bullous Pemphigoid at Saga Medical School Hospital.

1993 ◽  
Vol 55 (6) ◽  
pp. 1092-1095 ◽  
Author(s):  
Tatsurou TANAKA ◽  
Kiyohisa MOTOKI ◽  
Takahisa NISHI ◽  
Yutaka NARISAWA ◽  
Hiromu KOHDA
Keyword(s):  
Medical School ◽  
Bullous Pemphigoid ◽  
Statistical Study ◽  
Pemphigus Vulgaris

AI-Provided Instant Differential Diagnosis of Pemphigus Vulgaris and Bullous Pemphigoid: Qualitative Study (Preprint)

2020 ◽  
Author(s):  
Xiaoyu He ◽  
Juan Su ◽  
Guangyu Wang ◽  
Kang Zhang ◽  
Navarini Alexander ◽  
...  
Keyword(s):  
Artificial Intelligence ◽  
Early Diagnosis ◽  
Image Classification ◽  
Bullous Pemphigoid ◽  
Skin Diseases ◽  
Pemphigus Vulgaris ◽  
Classification Model ◽  
Clinical Image ◽  
Clinical Images ◽  
Multimodal Classification

BACKGROUND Pemphigus vulgaris (PV) and bullous pemphigoid (BP) are two rare but severe inflammatory dermatoses. Due to the regional lack of trained dermatologists, many patients with these two diseases are misdiagnosed and therefore incorrectly treated. An artificial intelligence diagnosis framework would be highly adaptable for the early diagnosis of these two diseases. OBJECTIVE Design and evaluate an artificial intelligence diagnosis framework for PV and BP. METHODS The work was conducted on a dermatological dataset consisting of 17,735 clinical images and 346 patient metadata of bullous dermatoses. A two-stage diagnosis framework was designed, where the first stage trained a clinical image classification model to classify bullous dermatoses from five common skin diseases and normal skin and the second stage developed a multimodal classification model of clinical images and patient metadata to further differentiate PV and BP. RESULTS The clinical image classification model and the multimodal classification model achieved an area under the receiver operating characteristic curve (AUROC) of 0.998 and 0.942, respectively. On the independent test set of 20 PV and 20 BP cases, our multimodal classification model (sensitivity: 0.85, specificity: 0.95) performed better than the average of 27 junior dermatologists (sensitivity: 0.68, specificity: 0.78) and comparable to the average of 69 senior dermatologists (sensitivity: 0.80, specificity: 0.87). CONCLUSIONS Our diagnosis framework based on clinical images and patient metadata achieved expert-level identification of PV and BP, and is potential to be an effective tool for dermatologists in remote areas in the early diagnosis of these two diseases.

A Case of Autoimmune Bullous Dermatosis with Features of Pemphigus Vulgaris and Bullous Pemphigoid

1995 ◽  
Vol 17 (5) ◽  
pp. 511-516 ◽  
Author(s):  
Satoshi Kore-eda ◽  
Yuji Horiguchi ◽  
Eriko Ohtoshi ◽  
Toshihiro Tanaka ◽  
Kimio Fujii ◽  
...  
Keyword(s):  
Bullous Pemphigoid ◽  
Pemphigus Vulgaris ◽  
Bullous Dermatosis

Bullous pemphigoid, cicatricial pemphigoid, and pemphigus vulgaris

1982 ◽  
Vol 54 (6) ◽  
pp. 656-662 ◽  
Author(s):  
George Laskaris ◽  
Alexandra Sklavounou ◽  
John Stratigos
Keyword(s):  
Bullous Pemphigoid ◽  
Pemphigus Vulgaris ◽  
Cicatricial Pemphigoid

Serum levels of BAFF are increased in bullous pemphigoid but not in pemphigus vulgaris

2006 ◽  
Vol 155 (2) ◽  
pp. 330-336 ◽  
Author(s):  
N. Asashima ◽  
M. Fujimoto ◽  
R. Watanabe ◽  
H. Nakashima ◽  
N. Yazawa ◽  
...  
Keyword(s):  
Bullous Pemphigoid ◽  
Pemphigus Vulgaris ◽  
Serum Levels

S2k guidelines for the treatment of pemphigus vulgaris/foliaceus and bullous pemphigoid

2015 ◽  
Vol 13 (8) ◽  
pp. 833-844 ◽  
Author(s):  
Rüdiger Eming ◽  
Michael Sticherling ◽  
Silke C. Hofmann ◽  
Nicolas Hunzelmann ◽  
Johannes S. Kern ◽  
...  
Keyword(s):  
Bullous Pemphigoid ◽  
Pemphigus Vulgaris ◽  
S2k Guidelines

Coexistence of pemphigus vulgaris and bullous pemphigoid in the upper aerodigestive tract

2006 ◽  
Vol 33 (2) ◽  
pp. 231-233 ◽  
Author(s):  
Keiji Tabuchi ◽  
Masatake Nomura ◽  
Hidekazu Murashita ◽  
Yasuhiro Fujisawa ◽  
Shigeki Tsuji ◽  
...  
Keyword(s):  
Bullous Pemphigoid ◽  
Pemphigus Vulgaris ◽  
Aerodigestive Tract ◽  
Upper Aerodigestive Tract
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