scholarly journals Physician severity scores correlate poorly with health‐related quality of life in patients with Hidradenitis Suppurativa

2020 ◽  
Vol 34 (11) ◽  
Author(s):  
K.R. van Straalen ◽  
I. van Trigt ◽  
E.P. Prens ◽  
H.H. van der Zee
Keyword(s):  
Quality Of Life ◽  
Hidradenitis Suppurativa ◽  
Health Related Quality ◽  
Severity Scores ◽  
Related Quality ◽  
Health Related

scholarly journals Quality of Life in Hidradenitis Suppurativa: An Update

2021 ◽  
Vol 18 (11) ◽  
pp. 6131
Author(s):  
Pavel V. Chernyshov ◽  
Andrew Y. Finlay ◽  
Lucia Tomas-Aragones ◽  
Francoise Poot ◽  
Francesca Sampogna ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Hidradenitis Suppurativa ◽  
Acne Inversa ◽  
Health Related Quality ◽  
Number Of Patients ◽  
Related Quality ◽  
Health Related ◽  
Positive Effect ◽  
Specific Health

Knowledge on hidradenitis suppurativa/acne inversa (HS) is rapidly increasing. HS has a profound impact on patients and their family life. Several factors, such as comorbidities, unemployment and HS severity, make this impact even more severe. The most widely used instrument to measure this impact is the dermatology-specific DLQI. We also identified six HS-specific health-related quality of life (HRQoL) instruments. Of them, HIDRAdisk, HSIA, HiSQOL and HSQoL-24 are better validated but there is still lack of experience of its use. Several treatment methods showed positive effect on patients’ HRQoL. Surgery remains a method with a substantial positive effect on HRQoL. Several studies confirming a positive effect of adalimumab on the HRQoL of patients with HS were published during the last three years. Data on the influence of several other biologics on HRQoL of HS patients are controversial or based on studies with a small number of patients.

The Effect of Sport-Related Concussion Injuries on Concussion Symptoms and Health-Related Quality of Life in Male and Female Adolescent Athletes: A Prospective Study

2019 ◽  
Vol 47 (14) ◽  
pp. 3514-3520
Author(s):  
Timothy A. McGuine ◽  
Adam Pfaller ◽  
Stephanie Kliethermes ◽  
Allison Schwarz ◽  
Scott Hetzel ◽  
...  
Keyword(s):  
Quality Of Life ◽  
High School ◽  
Health Related Quality ◽  
High School Athletes ◽  
Short Term ◽  
Female Patients ◽  
Severity Scores ◽  
Related Quality ◽  
Health Related

Background: Sport-related concussions (SRCs) are associated with short-term disablement, characterized as increased concussion symptoms and lower health-related quality of life (HRQoL). However, there are limited longitudinal data detailing how an SRC affects disablement beyond short-term injury recovery. Purpose: To longitudinally assess the effect of SRCs on symptoms and HRQoL in high school athletes through the 12 months after injury. Study Design: Cohort study; Level of evidence, 2. Methods: The 125 participants included high school athletes who sustained an SRC (female patients, 36%; mean ± SD age, 15.9 ± 1.1 years). The Post-concussion Symptom Scale (PCSS) from the Sport Concussion Assessment Tool–3 and the Pediatric Quality of Life Inventory 4.0 (PedsQL) were completed at enrollment and repeated at 24 to 72 hours (onset) and at 7 days (D7) after the SRC; on the date of return to play (RTP); and at 3, 6, and 12 months (M12) after the SRC. Scores at each time point were compared with the athletes’ own baseline via linear mixed models for repeated measures, controlling for age, sex, and history of previous SRC and with patient as a random effect. Results: Relative to baseline, female patients reported higher PCSS symptom and severity scores at onset ( P < .001) and D7 ( P < .001), while scores were not higher ( P > .05) for RTP through M12. As compared with baseline, male patients reported higher PCSS scores at onset ( P < .001) and D7 ( P = .003) and severity scores at onset ( P < .001) and D7 ( P = .016), while the symptom and severity scores were not higher ( P > .05) at RTP through M12. Female participants reported lower PedsQL physical scores at onset ( P = .006), while scores were not lower ( P > .05) from D7 through M12. Female psychosocial scores were not lower ( P > .05) at any time after the SRC, while the total PedsQL score was lower at onset ( P = .05) but not from D7 through M12. Male physical scores were lower at onset ( P < .001) and D7 ( P = .001) but not lower ( P > .05) from RTP through M12. Male psychosocial and PedsQL scores were unchanged ( P > .05) from baseline at onset through M12. Conclusion: After an SRC, high school athletes reported initial disablement (increased symptoms and lower HRQoL) through their RTP. However, after RTP, no similar disablement was detected through 12 months after injury.

27174 Health-related quality of life (HRQoL) in patients with hidradenitis suppurativa: A single center analysis

2021 ◽  
Vol 85 (3) ◽  
pp. AB30
Author(s):  
David A. Castillo Molina ◽  
Paula A. Chacón Jaramillo ◽  
Marcela Duran-Torres ◽  
Jesus D. Fierro Lozada ◽  
Daniela M. Molina Dorado ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Hidradenitis Suppurativa ◽  
Health Related Quality ◽  
Single Center ◽  
Related Quality ◽  
Health Related

Symptoms and health related quality of life in patients receiving matched therapy.

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. e21648-e21648
Author(s):  
Kirstin Anne Williams ◽  
Casey B. Williams ◽  
Luis Rojas ◽  
David Starks ◽  
Amy K. Krie ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Gynecologic Cancer ◽  
Health Related Quality ◽  
Symptom Experience ◽  
Self Assessment ◽  
Molecular Alterations ◽  
Severity Scores ◽  
Related Quality ◽  
Health Related

e21648 Background: Genomic sequencing is increasingly being used to select targeted agents that are matched to molecular alterations. Potential differences in symptom occurrence and severity as well as health related quality of life (HRQOL) between patients who receive matched therapy and those who do not receive matched therapy have not been previously explored. Methods: Existing data from the records of patients with breast or gynecologic cancer receiving outpatient care were used for this descriptive correlational research study. Descriptive statistics and multiple linear regression analyses were performed to address the study aims. Symptom occurrence and severity and HRQOL were measured with the previously validated Therapy-Related Symptom Checklist (TRSC) and HRQOL – Linear Analogue Self Assessment (HRQOL-LASA) respectively. A higher total TRSC score indicated high symptom occurrence and severity; a higher total HRQOL-LASA score indicated a high quality of life. Results: Patients receiving matched therapy had lower mean TRSC scores ( M= 14.7, SD= 10.1) compared to patients receiving not matched therapy ( M= 16.1, SD= 11.6). Patients receiving matched therapy had higher mean HRQOL-LASA scores ( M= 48.1, SD = 7.5), compared to patients receiving not matched therapy ( M= 45.4, SD= 9.1). Mean ratings were higher for patients receiving matched therapy on each individual HRQOL domain. Therapy type (matched, not matched) was not significantly associated with TRSC scores (B = -3.0, p= 0.18) or HRQOL scores (B = 2.0, p= 0.18) after controlling for person and disease factors. Conclusions: On average, patients receiving matched therapy had lower symptom occurrence and severity scores and higher HRQOL scores when compared to patients who were not receiving matched therapy. Type of therapy (matched, not matched) was not significantly associated with symptom or HRQOL scores. Study findings provide initial data about the symptom experience and HRQOL and for patients receiving matched therapy.

scholarly journals INFLUENCE OF NUTRITION ON DISEASE SEVERITY AND HEALTH-RELATED QUALITY OF LIFE IN ADULTS WITH SICKLE CELL DISEASE

2020 ◽  
Vol 13 (1) ◽  
pp. e2021007
Author(s):  
Sanaa Kamal ◽  
Moheyeldeen Mohamed Naghib ◽  
Jamaan Al Zahrani ◽  
Huda Hassan ◽  
Karim Abdel Aziz Moawado ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Sickle Cell Disease ◽  
Sickle Cell ◽  
Micronutrient Deficiencies ◽  
Health Related Quality ◽  
Cell Disease ◽  
Severity Scores ◽  
Related Quality ◽  
Health Related

Background & Aims: Sickle cell disease (SCD has a worldwide distribution and causes significant morbidity and mortality in children and adults. Few studies addressed the determinants of SCD severity in adults; therefore, we investigated the impact of nutrition on the outcome of SCD and health-related quality of life (HRQoL) in adult patients, Methods: In this longitudinal study, we recruited and prospectively followed 62 adults with SCD  (aged ?18 years) for a  median of 93 months. At entry and follow-up, patients provided medical and dietary history,  had a physical examination and anthropometric measurements, assessment of protein-energy intake, measurement of micronutrient levels, estimation of  SCD severity score, and determination of the HRQoL  (SF-26v2). The study outcome was a composite of hospitalization due to SCD crises or death. Results: At baseline, 42 (67.74%) patients had macro and, or micro-undernutrition (Group A), and 20 (32.26%) were well nourished. (Group B).  The   BMI and most anthropometric measurements were significantly lower in SCD patients compared to control subjects.  In several SCD patients, undernutrition resulted from reduced food intake and reduced absorption due to concomitant gastrointestinal disorders. Seventy percent of  SCD patients had vitamin D,  vitamin B12, and zinc deficiencies. Under-nourished patients had significantly higher SCD severity scores, frequent SCD related hospitalizations, higher mortality rates, and reduced HRQoL compared to well-nourished patients.  Protein-energy and micronutrient deficiencies were independent predictors of severe SCD and mortality. Correction of undernutrition and hydroxyurea therapy improved SCD severity scores and HRQoL. Conclusion: Patients with sickle cell disease have various degrees of macro and micro deficiencies, which increase SCD severity and hospitalizations and reduce the health-related quality of life. Early diagnosis and prompt correction of macro and micronutrient deficiencies need to be incorporated in the standard of care of SCD patients to improve the disease outcomes. 

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