Transposition cutaneous flap and split skin mesh graft as combined optimal treatment approach for giant neglected multicentric BCC of the shoulder

Author(s):  
G. Tchernev ◽  
I. Pidakev
1998 ◽  
Vol 79 (01) ◽  
pp. 1-7 ◽  
Author(s):  
Theodore Warkentin ◽  
Beng Chong ◽  
Andreas Greinacher

SummaryHeparin-induced thrombocytopenia (HIT) is a drug-induced, immunoglobulin-mediated thrombocytopenic disorder that is important for at least three reasons. First, it is a relatively common drug-induced immunohematologic adverse reaction. Second, it is frequently complicated by life- and limb-threatening thrombotic complications. And third, there remains uncertainty about the optimal treatment approach for these patients. Recently, there has emerged increasing consensus on such important issues as the frequency, pathogenesis, and diagnostic testing, which we will summarize here. Further, a greater appreciation of the activation of the coagulation pathways in this syndrome indicate a rationale to treatment approaches that emphasize thrombin inhibition (eg. danaparoid sodium; hirudin and its analogues).


1979 ◽  
Vol 2 (4) ◽  
pp. 269-275 ◽  
Author(s):  
Gary B. Cox ◽  
Stephen J. Carmichael ◽  
Cameron R. Dightman

Tumor Biology ◽  
2015 ◽  
Vol 36 (8) ◽  
pp. 6409-6416 ◽  
Author(s):  
Liang Wang ◽  
Zhong-jun Xia ◽  
Yu-jing Zhang ◽  
Hui-qiang Huang ◽  
Tong-yu Lin ◽  
...  

HPB ◽  
2020 ◽  
Vol 22 (1) ◽  
pp. 129-135 ◽  
Author(s):  
Sean P. Martin ◽  
Justin Drake ◽  
Michael M. Wach ◽  
Samantha M. Ruff ◽  
Laurence P. Diggs ◽  
...  

Author(s):  
S.V. Kolesnik ◽  
◽  
A.S. Zhuravlev ◽  
A.I. Kolesnik ◽  
S.A. Kakunina ◽  
...  

Introduction. Age-related macular degeneration (AMD) is one of the leading causes of irreversible vision loss among older patients. Since the introduction of anti-VEGF therapy, retinal specialists have been able to maintain or improve vision in patients with AMD. However, anti-VEGF therapy is ineffective in a certain percentage of patients. In 25-35% of cases of wet AMD, secondary epiretinal membranes (ERM) in the macular region are found. Anti-VEGF therapy has been found to be less effective in the treatment of wet AMD with ERM. Optimal treatment tactics for this combined pathology remains a matter of debate. Purpose. To evaluate the efficacy of different combined treatment approaches to patients with wet AMD and ERM. Methods. Study was performed on 2 eyes of 2 patients with ERM and AMD, wet form. Patients were divided in two groups. First patient received one loading dose of anti-VEGF drug (ranibizumab) and after that underwent standart pars plana vitrectomy (PPV) with removal of epiretinal and inner limiting membrane (ILM). Anti-VEGF therapy than was continued according to pro re nata regimen. Second patient underwent standart PPV with removal of ERM and ILM first. After the surgery, loading dose of anti-VEGF drug was injected. Anti-VEGF therapy than was continued according to pro re nata regimen. Results. After treatment, there was a decrease in central retinal thickness in both patients, but an increase in maximum corrected visual acuity was observed only in first patient. Conclusions. Based on the results of the performed study, the most optimal treatment approach to patients with wet AMD and ERM consisted of a single loading dose of anti-VEGF drug injection followed by PPV with removal of ERM and ILM and further continuation of anti-VEGF therapy for wet AMD. However, further research is needed to form a final conclusion about the effectiveness of the chosen treatment tactic. Key words: epiretinal fibrosis, AMD, CNVM, anti-VEGF


2015 ◽  
Vol 17 (4) ◽  
Author(s):  
Xuguang Chen ◽  
Jennifer R. Eads ◽  
John B. Ammori ◽  
Aryavarta M. Kumar ◽  
Tithi Biswas ◽  
...  

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