Evaluation of the appropriate surgical margin for pigmented basal cell carcinoma according to the risk factors for recurrence: a single-institute retrospective study in Japan

2018 ◽  
Vol 32 (12) ◽  
pp. e453-e455 ◽  
Author(s):  
Y. Nakamura ◽  
K. Tanese ◽  
I. Hirai ◽  
K. Kameyama ◽  
Y. Kawakami ◽  
...  
Keyword(s):  
Risk Factors ◽  
Retrospective Study ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Surgical Margin ◽  
Risk Factors For Recurrence

scholarly journals Clinicopathological analysis of basal cell carcinoma – A retrospective study

2020 ◽  
Vol 0 ◽  
pp. 1-5
Author(s):  
Roshan Mary George ◽  
Mohamed Nazeer ◽  
Sebastian Criton ◽  
Usha Mary Abraham ◽  
Abel Francis
Keyword(s):  
Risk Factors ◽  
Retrospective Study ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Sun Exposure ◽  
Superficial Spreading ◽  
Histopathological Features ◽  
History Of ◽  
Superficial Spreading Type

Objectives: The objective of the study was to analyze the demographic profile, histopathological features, risk factors, and recurrence rates in patients with basal cell carcinoma. Materials and Methods: A retrospective study was conducted from 2012 to October 2018 in 29 patients with histopathologically confirmed basal cell carcinoma. All the patients had undergone either excision or cryotherapy as per the institution protocol. Information on the history of the disease, occupation, history of sun exposure and clinical and histopathological features were collected and analyzed. Results: A female preponderance was found (n = 18, 62.1%), majority of the patients were unemployed (44.8%), 19 patients (65.5%) gave a history of sun exposure, and the nose was the most common site of disease. Ten females (34.5%) did not have any excessive exposure to the sun, but gave a history of exposure to heat and fumes in the kitchen. Six patients (20.7%) had a preexisting nevus at the same site and superficial spreading type was the most common histopathological type (n = 24, 82.8%). Excision gave the best result. Four patients (13.8%) had recurrence of the disease. Limitations: Small sample size was the major limitation. The risk factors and occupation could not be analyzed objectively. Conclusion: This is a pioneer study from Kerala. A female preponderance (62.1%) was observed. The role of heat, fumes, type of oven, and use of reheated oil in cooking as risk factors for the development of BCC needs analysis in future studies. Superficial spreading type was the most common pattern observed in histopathology slides (82.8%). Excision gives near-complete clearance and a good cosmetic result with less risk of recurrence.

Risk factors associated with relapse of eyelid basal cell carcinoma: results from a retrospective study of 142 patients

2017 ◽  
Vol 27 (4) ◽  
pp. 363-368 ◽  
Author(s):  
Giusy Fatigato ◽  
Silvano Capitani ◽  
Daniela Milani ◽  
Silvia Grassilli ◽  
Ayman AM Alameen ◽  
...  
Keyword(s):  
Risk Factors ◽  
Retrospective Study ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Factors Associated

scholarly journals Dermoscopic Features of Basal Cell Carcinoma

2018 ◽  
Vol 35 (4) ◽  
pp. 273-281
Author(s):  
Danica Tiodorović ◽  
Andrija Jović ◽  
Danijela Popović ◽  
Hristina Kocić ◽  
Aleksandra Ignjatović ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Basal Cell ◽  
Skin Tumors ◽  
Clinical Type ◽  
Reliable Diagnosis ◽  
The Moment

Abstract The aim of this study was to analyze the dermoscopic features in patients with pathohistologically confirmed basal cell carcinoma (BCC). Our retrospective study included 54 patients with 76 BCCs in total, diagnosed in 2016 and 2017. All lesions were classified into four clinical types: nodular, pigmented, superficial and infiltrative. Digital dermoscopic images were evaluated by three observers. We selected five dermoscopic features for analysis, including: the absence of pigment network, the presence of arborizing vessels, blue-gray globules and ovoid nests, leaf-like areas and ulcerations. In the total of 54 patients, there were 22 females and 32 males. At the moment of establishing the diagnosis, the patients’ age was in the range from 31 to 84 years (median age 67 years). The most frequent clinical type was the nodular type with 28 confirmed diagnoses. Nodular BCC was more frequently localized on the head and neck areas compared to the trunk and limbs (p < 0.01). Dermoscopically, the absence of pigmented network was verified in all cases. Arborizing vessels were present in 71 (93.4%) lesions, blue-gray globules and ovoid nests in 33 (42.1%), ulcerations in 44 (57.9%), and leaf-like areas in 5 (6.6%) lesions. Blue-gray globules and ovoid nests were significantly frequent in pigmented BCC in comparison to other clinical types of BCC (p < 0.01). In conclusion, using dermoscopy, it is entirely possible to make a reliable diagnosis of BCC as well as to differentiate it from others skin tumors.

scholarly journals Single versus Multiple Level Sectioning for the Subtyping of Basal-Cell Carcinoma: A Retrospective Study

Dermatology ◽  
2019 ◽  
Vol 236 (3) ◽  
pp. 237-240 ◽  
Author(s):  
Lieke C.J. van Delft ◽  
Patty J. Nelemans ◽  
Myrurgia Abdul Hamid ◽  
Nicole W.J. Kelleners-Smeets
Keyword(s):  
Retrospective Study ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Primary Outcome ◽  
Punch Biopsy ◽  
Appropriate Treatment ◽  
Treatment Objective ◽  
Optimal Approach ◽  
Single Versus

Background: The histological subtype of basal-cell carcinoma (BCC) is often based on a punch biopsy; only a small part is evaluated, possibly leading to misclassification. Consensus on the optimal approach to process punch biopsies is lacking, though accurate subtyping is important for appropriate treatment. Objective: The aim is to investigate whether evaluating 4 levels of a punch biopsy instead of 1 or 2 levels leads to more accurate subtyping of BCC. Methods: In a retrospective study we evaluated 87 punch biopsies of histologically confirmed BCCs. The primary outcome was the proportion of “more aggressive” BCCs (nonsuperficial vs. superficial, infiltrative vs. nodular subtype) that was missed by evaluation on 1 or 2 levels, using 4-level diagnosis as reference standard. Results: Eighty-five cases were available for analysis. Subtyping based on 1 level resulted in discrepancies with 4-level diagnosis in 16.5% of all cases. Underdiagnosis occurred in 14 of 58 nonsuperficial BCCs (24.1%, 95% CI: 13.9–37.2). Seven of 38 nodular BCCs (18.4%, 95% CI: 7.74–34.3) were diagnosed as superficial in 1 level, and 7 of 20 infiltrative BCCs (35%, 95% CI: 15.4–59.2) were diagnosed as superficial (n = 2) or nodular (n = 5) in 1 level. Conclusion: In order to maximize correct subtyping and plan appropriate treatment, we advise to evaluate at least 2, but preferably more, levels of a punch biopsy to determine the BCC subtype.

scholarly journals Basal-Cell Carcinoma Incidence and Associated Risk Factors in US Women and Men

2013 ◽  
Vol 178 (6) ◽  
pp. 890-897 ◽  
Author(s):  
S. Wu ◽  
J. Han ◽  
W.-Q. Li ◽  
T. Li ◽  
A. A. Qureshi
Keyword(s):  
Risk Factors ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Associated Risk Factors

scholarly journals Use of Cytology in the Diagnosis of Basal Cell Carcinoma Subtypes

2020 ◽  
Vol 9 (3) ◽  
pp. 612
Author(s):  
Paola Pasquali ◽  
Gonzalo Segurado-Miravalles ◽  
Mar Castillo ◽  
Ángeles Fortuño ◽  
Susana Puig ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Inverse Correlation ◽  
Basal Cells ◽  
White Population ◽  
First Line ◽  
Common Skin ◽  
Cytological Features

Background: Basal cell carcinoma (BCC) is the most common skin cancer in the white population. Nonsurgical treatments are first-line alternatives in superficial BCC (sBCC); therefore, differentiating between sBCC and non-sBCC is of major relevance for the clinician. Scraping cytology possesses several advantages, such as an earlier diagnosis and scarring absence, in comparison to a biopsy. Nevertheless, previous studies reported difficulties in differentiating the different BCC subtypes. The objective of this study was to determine the capability and accuracy of scraping cytology to differentiate between sBCC and non-sBCC. Methods: In this retrospective study, cytological samples of histologically confirmed BCC were examined. Select cytological features were correlated to BCC subtypes (sBCC or non-sBCC). Results: A total of 84 BCC samples were included (29 sBCC; 55 non-sBCC). An inverse correlation between the diagnosis of sBCC and the presence of mucin, dehiscence, and grade of atypia in the basal cells was observed. The presence of medium and large basal cell clusters correlated directly to a sBCC diagnosis. The presence of clear cells is strongly associated with sBCC. Therefore, Conclusion: Scraping cytology is reliable in differentiating sBCC from other BCC subtypes.

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