scholarly journals Sinecatechins ointment 10% (Veregen®) for genital warts: percutaneous penetration of epigallocatechin gallate concentrations in the stratum corneum collected by adhesive tape stripping method

2018 ◽  
Vol 32 (9) ◽  
pp. e357-e358
Author(s):  
H.J.C. de Vries ◽  
M. Soltanipoor ◽  
S. Kezic ◽  
C.E. Vergunst
Keyword(s):  
Stratum Corneum ◽  
Epigallocatechin Gallate ◽  
Genital Warts ◽  
Percutaneous Penetration ◽  
Tape Stripping ◽  
Adhesive Tape ◽  
Stripping Method

Tape Stripping Method and Stratum Corneum

2004 ◽  
pp. 531-547 ◽  
Author(s):  
Hongbo Zhai ◽  
Howard Maibach ◽  
Myeong Jun Choi
Keyword(s):  
Stratum Corneum ◽  
Tape Stripping ◽  
Stripping Method

scholarly journals Evaluation of the Stratum Corneum Exfoliated by Tape Stripping Method (No. 1)

1997 ◽  
Vol 32 (1) ◽  
pp. 33-42 ◽  
Author(s):  
Masayuki Matsumoto ◽  
Shoji Hayashi ◽  
Seiichi Arai
Keyword(s):  
Stratum Corneum ◽  
Tape Stripping ◽  
Stripping Method

scholarly journals Tape stripping method is useful for the quantification of antimicrobial peptides on the human skin surface including the stratum corneum

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Shigeyuki Ono ◽  
Nobuhiko Eda ◽  
Takuya Mori ◽  
Atsuko Otsuka ◽  
Nobuhiro Nakamura ◽  
...  
Keyword(s):  
Antimicrobial Peptides ◽  
Stratum Corneum ◽  
Human Skin ◽  
Significant Positive Correlation ◽  
Skin Surface ◽  
Tape Stripping ◽  
Established Method ◽  
Positive Correlation ◽  
Physiological Importance ◽  
Stripping Method

Abstract Antimicrobial peptides (AMPs) play an important role in innate immunity in human skin. It is known that AMPs mainly function in the stratum corneum. Therefore, AMP concentrations in the stratum corneum need to be precisely measured to clarify functional and physiological importance of AMPs in cutaneous defence. Tape stripping (TS) is a well-established method by which components in the stratum corneum can be collected. However, the usefulness of the TS method for measuring AMP concentration in human skin remains unclear. Therefore, we compared it with another popular method, skin rinsing, which had been established as a method for measuring AMP concentration in human skin. When investigated on healthy medial forearm using RNase 7, which is one of the typical AMPs, as an index, there was a significant positive correlation between RNase 7 concentrations measured by the TS method at adjacent forearm sites, demonstrating the reproducibility of the TS method. Next, a significant positive correlation was detected in RNase 7 concentrations measured using the TS and the skin rinsing method, indicating that the TS method is comparable to the skin rinsing method. Thus, we speculate that the TS method is useful for measuring AMP concentration in human skin.

scholarly journals Solvent effects on the harvesting of stratum corneum from hairless mouse skin through adhesive tape stripping in vitro

1991 ◽  
Vol 68 (1-3) ◽  
pp. 127-133 ◽  
Author(s):  
Tsai Jui-Chen ◽  
Markus J. Cappel ◽  
Norman D. Weiner ◽  
Gordon L. Flynn ◽  
James Ferry
Keyword(s):  
Stratum Corneum ◽  
Solvent Effects ◽  
Mouse Skin ◽  
Hairless Mouse ◽  
Tape Stripping ◽  
Adhesive Tape ◽  
Hairless Mouse Skin

scholarly journals Assessment of dermal bioavailability: predicting the input function for topical glucocorticoids using stratum corneum sampling

2021 ◽  
Author(s):  
Andrea Pensado ◽  
Anita McGrogan ◽  
K. A. Jane White ◽  
Annette L. Bunge ◽  
Richard H. Guy ◽  
...  
Keyword(s):  
Stratum Corneum ◽  
Elimination Rate ◽  
Input Function ◽  
Tape Stripping ◽  
Viable Epidermis ◽  
Quantitative Metrics ◽  
Topical Glucocorticoids ◽  
Stripping Method ◽  
Drug Flux ◽  
Larger Sample

AbstractPredicting the dermal bioavailability of topically delivered drugs is challenging. In this work, minimally invasive stratum corneum (SC) sampling was used to quantify the delivery of betamethasone valerate (BMV) into the viable skin. Betnovate® cream (0.1% w/w BMV) was applied at three doses (2, 5, and 10 mg cm−2) to the ventral forearms of 12 healthy volunteers. The mass of drug in the SC was measured using a validated tape-stripping method (a) after a 4-h “uptake” period, and (b) following a 6-h “clearance” period subsequent to cream removal. Concomitantly, the skin blanching responses to the same doses were assessed with a chromameter over 22 h post-application. BMV uptake into the SC was significantly higher for the 5 mg cm−2 dose compared to those of 2 and 10 mg cm−2. In all cases, ~30% of the drug in the SC at the end of the uptake period was cleared in the subsequent 6 h. From the SC sampling data, the average drug flux into the viable epidermis and its first-order elimination rate constant from the SC were estimated as 4 ng cm−2 h−1 and 0.07 h−1, respectively. In contrast, skin blanching results were highly variable and insensitive to the dose of cream applied. The SC sampling method was able to detect a 50% difference between two applied doses with 80% power; detection of a 20% difference would require a larger sample size. SC sampling enabled quantitative metrics describing corticosteroid delivery to the viable epidermis to be determined. Graphical abstract

Adhesive tape stripping reveals differences in stratum corneum cohesion between Caucasians, Blacks, and Hispanics as a function of age

2012 ◽  
pp. 262-267
Author(s):  
Kaley A. Myer ◽  
Frank Dreher ◽  
Alessandra Pelosi ◽  
Kazuhiro Mio ◽  
Enzo Berardesca ◽  
...  
Keyword(s):  
Stratum Corneum ◽  
Tape Stripping ◽  
Adhesive Tape
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