The importance of dermoscopy for the diagnosis of acquired bilateral telangiectatic macules: the angioid streak pattern reveals underlying chronic liver disease

2017 ◽  
Vol 32 (9) ◽  
pp. 1597-1601
Author(s):  
G.-W. Kim ◽  
K. Shin ◽  
T.-W. Kim ◽  
H.-S. You ◽  
H.-J. Jin ◽  
...  
1999 ◽  
Vol 229 (2) ◽  
pp. 210-215 ◽  
Author(s):  
Olivier Farges ◽  
Benoit Malassagne ◽  
Jean François Flejou ◽  
Silvio Balzan ◽  
Alain Sauvanet ◽  
...  

2013 ◽  
Vol 50 (2) ◽  
pp. 97-100 ◽  
Author(s):  
Fernanda Maria Farage OSÓRIO ◽  
Gabriel Martin LAUAR ◽  
Agnaldo Soares LIMA ◽  
Paula Vieira Teixeira VIDIGAL ◽  
Teresa Cristina Abreu FERRARI ◽  
...  

Context Studies on epidemiology of hepatocellular carcinoma and modalities of therapy used to treat this condition are scarce in Brazil. Our aim was to characterize hepatocellular carcinoma according to etiology of the underlying chronic liver disease, and treatment modalities, in a referral center in Brazil. Methods All cases of hepatocellular carcinoma registered in the Department of Pathology during a 12-year period (1998-2010) were included. Demographic data, etiology of the underlying liver disease and treatment performed were collected. Results This case series included 215 patients, mean age 57.3 (± 14.1) years, 164 (76.2 %) male. Virus C and virus B infection were detected in 88 (43%) and 47 (23%) patients, respectively. Ethanol abuse alone or combined with other etiologies was identified in 64 (32%) individuals. Schistosomiasis was found in 18 (9%) patients. Liver transplantation was the treatment of choice in 112 (51%) patients. This procedure was more frequently performed in hepatitis C virus-related hepatocellular carcinoma (70%) than B virus-related hepatocellular carcinoma (17%). Tumor resection was performed in 40 (18%) individuals, ethanol injection or thermo ablation in 18 (14%), and chemoembolization in 14 (7%). In 40 (19.4%) patients no treatment was performed and this percentage remained constant over the years. Conclusions Chronic hepatitis C, followed by ethanol abuse and chronic hepatitis B were the leading causes of underlying chronic liver disease associated with hepatocellular carcinoma. The results show a trend of increasing incidence of hepatocellular carcinoma; however, the proportion of untreated patients remained constant over the analyzed period.


2021 ◽  
Vol 2021 ◽  
pp. 1-5
Author(s):  
Samrat Ray ◽  
Suvendu S. Jena ◽  
Amitabh Yadav ◽  
Sri Aurobindo Prasad Das ◽  
Naimish N. Mehta ◽  
...  

Introduction. Whipple’s pancreatoduodenectomy (PD) is a formidable operation, associated with a high risk of morbidity and mortality. In the setting of an underlying chronic liver disease, the incidence of complications and mortality increases manifold. Patients and Outcomes. Of the 112 Whipple’s PD performed between 2018 to 2020 at a high-volume HPB and liver transplant centre, 4 patients underwent the surgery in the background of an underlying chronic liver disease (CLD). All except one were performed in Child’s A cirrhotics. There was a single 30-day mortality in this series of 4 patients that occurred in the background of Child’s B cirrhosis. On follow-up at 1 year, there was one more mortality in the series, owing to liver decompensation following chemotherapy. Conclusion. Judicious preoperative selection criteria, adequate preoperative nutritional and physiological optimisation, and prudent weighing of risk vs. benefit of undergoing Whipple’s PD in periampullary malignancies in the setting of CLD are the major determinants of the surgical outcome.


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