The efficacy and safety of apremilast, etanercept and placebo in patients with moderate-to-severe plaque psoriasis: 52-week results from a phase IIIb, randomized, placebo-controlled trial (LIBERATE)

K. Reich; M. Gooderham; L. Green; A. Bewley; Z. Zhang; I. Khanskaya; R.M. Day; J. Goncalves; K. Shah; V. Piguet; J. Soung

doi:10.1111/jdv.14015

The efficacy and safety of apremilast, etanercept and placebo in patients with moderate-to-severe plaque psoriasis: 52-week results from a phase IIIb, randomized, placebo-controlled trial (LIBERATE)

Journal of the European Academy of Dermatology and Venereology ◽

10.1111/jdv.14015 ◽

2016 ◽

Vol 31 (3) ◽

pp. 507-517 ◽

Cited By ~ 62

Author(s):

K. Reich ◽

M. Gooderham ◽

L. Green ◽

A. Bewley ◽

Z. Zhang ◽

...

Keyword(s):

Plaque Psoriasis ◽

Controlled Trial ◽

Efficacy And Safety ◽

Severe Plaque Psoriasis ◽

Phase Iiib

Download Full-text

Efficacy and safety of total glucosides of paeony combined with acitretin in the treatment of moderate-to-severe plaque psoriasis: a double-blind, randomised, placebo-controlled trial

European Journal of Dermatology ◽

10.1684/ejd.2016.2946 ◽

2017 ◽

Vol 27 (2) ◽

pp. 150-154 ◽

Cited By ~ 5

Author(s):

Chen Yu ◽

Xueli Fan ◽

Zhenlu Li ◽

Xiaoming Liu ◽

Gang Wang

Keyword(s):

Plaque Psoriasis ◽

Controlled Trial ◽

Efficacy And Safety ◽

Double Blind ◽

Severe Plaque Psoriasis ◽

Total Glucosides Of Paeony

Download Full-text

Efficacy and safety of apremilast, an oral phosphodiesterase 4 inhibitor, in patients with moderate‐to‐severe plaque psoriasis over 52 weeks: a phase III, randomized controlled trial (ESTEEM 2)

British Journal of Dermatology ◽

10.1111/bjd.14164 ◽

2015 ◽

Vol 173 (6) ◽

pp. 1387-1399 ◽

Cited By ~ 201

Author(s):

C. Paul ◽

J. Cather ◽

M. Gooderham ◽

Y. Poulin ◽

U. Mrowietz ◽

...

Keyword(s):

Randomized Controlled Trial ◽

Plaque Psoriasis ◽

Controlled Trial ◽

Phase Iii ◽

Efficacy And Safety ◽

Severe Plaque Psoriasis ◽

Phosphodiesterase 4 ◽

Randomized Controlled ◽

Phosphodiesterase 4 Inhibitor

Download Full-text

Efficacy and safety of apremilast with or without topical or phototherapy: Subanalysis of the population with < PASI-75 in the ESTEEM 1 phase 3, randomized, controlled trial in patients with moderate to severe plaque psoriasis

Journal of the American Academy of Dermatology ◽

10.1016/j.jaad.2016.02.963 ◽

2016 ◽

Vol 74 (5) ◽

pp. AB246 ◽

Cited By ~ 1

Keyword(s):

Randomized Controlled Trial ◽

Plaque Psoriasis ◽

Controlled Trial ◽

Efficacy And Safety ◽

Phase 3 ◽

Severe Plaque Psoriasis ◽

Randomized Controlled

Download Full-text

Efficacy and safety of efalizumab in adults with moderate to severe plaque psoriasis and hand and foot involvement: A prospective, 24-week, open-label phase IIIb/IV clinical trial in patients from Latin America

Journal of the American Academy of Dermatology ◽

10.1016/j.jaad.2007.10.578 ◽

2008 ◽

Vol 58 (2) ◽

pp. AB131

Keyword(s):

Clinical Trial ◽

Latin America ◽

Plaque Psoriasis ◽

Efficacy And Safety ◽

Open Label ◽

Severe Plaque Psoriasis ◽

Phase Iiib ◽

Open Label Phase

Download Full-text

Safety of efalizumab in adults with chronic moderate to severe plaque psoriasis: A phase IIIb, randomized, controlled trial

International Journal of Dermatology ◽

10.1111/j.1365-4632.2006.02777.x ◽

2006 ◽

Vol 45 (5) ◽

pp. 605-614 ◽

Cited By ~ 53

Author(s):

Kim A. Papp ◽

Reni Bressinck ◽

Scott Fretzin ◽

Bernard Goffe ◽

Steven Kempers ◽

...

Keyword(s):

Randomized Controlled Trial ◽

Plaque Psoriasis ◽

Controlled Trial ◽

Severe Plaque Psoriasis ◽

Randomized Controlled ◽

Phase Iiib

Download Full-text

Apremilast, an oral phosphodiesterase 4 (PDE4) inhibitor, in patients with moderate to severe plaque psoriasis: Results of a phase III, randomized, controlled trial (Efficacy and Safety Trial Evaluating the Effects of Apremilast in Psoriasis [ESTEEM] 1)

Journal of the American Academy of Dermatology ◽

10.1016/j.jaad.2015.03.049 ◽

2015 ◽

Vol 73 (1) ◽

pp. 37-49 ◽

Cited By ~ 273

Author(s):

Kim Papp ◽

Kristian Reich ◽

Craig L. Leonardi ◽

Leon Kircik ◽

Sergio Chimenti ◽

...

Keyword(s):

Randomized Controlled Trial ◽

Plaque Psoriasis ◽

Controlled Trial ◽

Phase Iii ◽

Pde4 Inhibitor ◽

Efficacy And Safety ◽

Severe Plaque Psoriasis ◽

Phosphodiesterase 4 ◽

Randomized Controlled

Download Full-text

Faculty Opinions recommendation of Efficacy and safety of apremilast, an oral phosphodiesterase 4 inhibitor, in patients with moderate-to-severe plaque psoriasis over 52 weeks: a phase III, randomized controlled trial (ESTEEM 2).

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.725781037.793521633 ◽

2016 ◽

Author(s):

Gil Yosipovitch ◽

Leigh Nattkemper

Keyword(s):

Randomized Controlled Trial ◽

Plaque Psoriasis ◽

Controlled Trial ◽

Phase Iii ◽

Efficacy And Safety ◽

Severe Plaque Psoriasis ◽

Phosphodiesterase 4 ◽

Randomized Controlled ◽

Phosphodiesterase 4 Inhibitor

Download Full-text

Efficacy and safety of efalizumab in patients with chronic moderate to severe plaque psoriasis: Results from a postapproval phase IIIb/IV study (control II)

Journal of the American Academy of Dermatology ◽

10.1016/j.jaad.2008.11.777 ◽

2009 ◽

Vol 60 (3) ◽

pp. AB179

Keyword(s):

Plaque Psoriasis ◽

Efficacy And Safety ◽

Severe Plaque Psoriasis ◽

Phase Iiib

Download Full-text

Efficacy and safety of fumaric acid esters in young patients aged 10 to 17 years with moderate‐to‐severe plaque psoriasis – A randomised, double‐blinded, placebo‐controlled trial

British Journal of Dermatology ◽

10.1111/bjd.19747 ◽

2020 ◽

Author(s):

H. Hamm ◽

D. Wilsmann‐Theis ◽

A. Tsianakas ◽

T. Gambichler ◽

K. Taipale ◽

...

Keyword(s):

Fumaric Acid ◽

Plaque Psoriasis ◽

Controlled Trial ◽

Young Patients ◽

Efficacy And Safety ◽

Severe Plaque Psoriasis ◽

Fumaric Acid Esters ◽

Double Blinded ◽

Acid Esters

Download Full-text

Efficacy and Safety of Efalizumab in Patients with Moderate-to-Severe Plaque Psoriasis Resistant to Previous Anti-Psoriatic Treatment: Results of a Multicentre, Open-label, Phase IIIb/IV Trial

Archives of Drug Information ◽

10.1111/j.1753-5174.2009.00026.x ◽

2010 ◽

Vol 3 (1) ◽

pp. 9-18 ◽

Cited By ~ 7

Author(s):

Torello Lotti ◽

Sergio Chimenti ◽

Andreas Katsambas ◽

Jean-Paul Ortonne ◽

Louis Dubertret ◽

...

Keyword(s):

Plaque Psoriasis ◽

Efficacy And Safety ◽

Treatment Results ◽

Open Label ◽

Severe Plaque Psoriasis ◽

Phase Iiib ◽

Open Label Phase

Download Full-text