A case of inflammatory myofibroblastic tumour of the right labium majus

2015 ◽  
Vol 30 (7) ◽  
pp. 1250-1252
Author(s):  
M. Pellegrino ◽  
L. Feci ◽  
P. Taddeucci ◽  
V. Mancini ◽  
E. Trovato ◽  
...  
Keyword(s):  
Inflammatory Myofibroblastic Tumour ◽  
The Right ◽  
Labium Majus

Inflammatory myofibroblastic tumour of the conjunctiva masquerading as ocular surface squamous neoplasia

2020 ◽  
pp. 112067212097361
Author(s):  
Manpreet Singh ◽  
Manu Saini ◽  
Debajyoti Chatterjee ◽  
Aditi Mehta ◽  
Manpreet Kaur ◽  
...  
Keyword(s):  
Amniotic Membrane ◽  
Ocular Surface ◽  
Surgical Excision ◽  
Excision Biopsy ◽  
Inflammatory Myofibroblastic Tumour ◽  
Complete Surgical Excision ◽  
Oral Steroids ◽  
Rare Site ◽  
The Right

A 63-year-male had painless, progressive, yellowish-pink, immobile conjunctival mass with prominent feeder vessels in the right eye of 1-year duration. The rest of the ophthalmic examination was unremarkable. MRI showed no extension into orbit or extraocular muscles. An excision biopsy with the amniotic membrane patch was performed. Histopathology confirmed inflammatory myofibroblastic tumour (IMT) with SMA and calponin positivity on immunohistochemistry. Complete surgical excision, amniotic membrane, and oral steroids provided long-term relief from recurrence. The conjunctiva is a rare site for IMT, and IMT should be kept in the differentials for atypical cases of ocular surface neoplasia.

Inflammatory myofibroblastic tumour of the tonsil: case report and literature review

2010 ◽  
Vol 124 (10) ◽  
pp. 1123-1125 ◽  
Author(s):  
J C Magill ◽  
M S Ferguson ◽  
C R Butler ◽  
A Sandison ◽  
W E Grant
Keyword(s):  
Case Report ◽  
Pregnant Woman ◽  
English Language ◽  
Spindle Cell Carcinoma ◽  
Inflammatory Myofibroblastic Tumour ◽  
Complete Excision ◽  
Recommended Treatment ◽  
History Of ◽  
High Grade Carcinoma ◽  
The Right

AbstractObjective:We present the first reported case in the English language literature of an inflammatory myofibroblastic tumour of the right tonsil in a young, pregnant woman, and we report a management strategy for this enigmatic entity.Case report:A 28-year-old, pregnant woman presented with a 10-day history of odynophagia despite a course of antibiotics. Examination revealed a grade II, erythematous right tonsil with ulceration on the upper pole. A biopsy was arranged, and initial evaluation was suggestive of spindle cell carcinoma. However, this diagnosis was reviewed after immunohistochemical staining confirmed an inflammatory myofibroblastic tumour. Subsequent complete excision was undertaken using CO2laser.Conclusion:Clinically, inflammatory myofibroblastic tumour of the tonsil is known to be locally aggressive and can present in a manner not dissimilar to a high grade carcinoma of the tonsil. As a result, the recommended treatment is complete local excision with careful follow up.

scholarly journals Spontaneous vulvar hematoma as a rare manifestation of congenital hypofibrinogenemia. Case report

Case reports ◽  
2019 ◽  
Vol 5 (2) ◽  
pp. 155-161
Author(s):  
Sebastián Felipe Sierra-Umaña ◽  
Rafael García-Sanchez ◽  
Laura Camila Urrutia-Corredor ◽  
Jessica Tatiana Olarte-Luis ◽  
Dolli Yineth Cáceres-Galíndez
Keyword(s):  
Factor I ◽  
Total Absence ◽  
Quantitative Factor ◽  
First Case ◽  
Target Values ◽  
Rare Manifestation ◽  
History Of ◽  
Congenital Hypofibrinogenemia ◽  
The Right ◽  
Labium Majus

Introduction: Congenital fibrinogen disorders are rare conditions in which there are quantitative and qualitative alterations of factor I; the vast majority of patients are asymptomatic.Case presentation: A 19-year-old female patient with a history of congenital hypofibrinogenemia presented with spontaneous vulvar hematoma along with hypotension, tachycardia, stupor and hematoma of 20cm in the right labium majus. On admission, the young woman had hemoglobin 6.6 g/dL, fibrinogen 74 mg/dL and prolonged clotting times. She received red blood cells transfusion and cryoprecipitates, followed by surgical drainage and intravenous fibrinogen replacement, adjusting the dose according to fibrinogen levels in plasma. The patient presented progressive improvement without hemorrhagic recurrence and fibrinogen levels within the target values until hospital discharge.Discussion: Afibrinogenemia and hypofibrin­ogenemia are part of the quantitative factor I disorders; in the first case, there is total absence of circulating fibrinogen, and in the second case the levels are below 150 mg/dL. Sponta­neous vulvar hematoma as a severe hemorrhagic manifestation is not frequent in symptomatic patients; its treatment is based on fibrinogen replacement in an individualized manner and surgical management when required.Conclusion: Hypofibrinogenemia is a rare dis­ease, and fibrinogen replacement is one of the mainstays of treatment.

scholarly journals Inflammatory myofibroblastic tumour in the right ventricle of a 66-year-old man

2019 ◽  
Vol 29 (6) ◽  
pp. 967-968
Author(s):  
Diego Monzón Díaz ◽  
Gregorio Cuerpo Caballero ◽  
Angela Irabien Ortiz ◽  
Ángel Gonzalez Pinto
Keyword(s):  
Surgical Technique ◽  
Right Ventricle ◽  
Surgical Resection ◽  
Rare Entity ◽  
Inflammatory Myofibroblastic Tumour ◽  
Review Of The Literature ◽  
First Case ◽  
The Right

Abstract Herein, we present the case of a 66-year-old man with an inflammatory myofibroblastic tumour. An inflammatory myofibroblastic tumour is an extremely rare entity, with only 60 cases having been reported to date in the literature. The origin of this type of tumour is unknown and the treatment of choice is surgical resection. We present the surgical technique of our case and a review of the literature regarding this tumour. This is the first case described in a man above 60 years of age with a tumour located in the right ventricle.

scholarly journals Aggressive angiomyxoma of the vulva - An Enigma in Clinical Practice

2016 ◽  
Vol 29 (1) ◽  
pp. 46-48
Author(s):  
Farhana Dewan ◽  
Fahmida Khan ◽  
Fahmida Sharmin Joty ◽  
Mariha Alam Chowdhury ◽  
Sanjukta Chowdhury ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Surgical Treatment ◽  
Benign Tumor ◽  
Benign Lesion ◽  
Vascular Tumor ◽  
Aggressive Angiomyxoma ◽  
The World ◽  
The Right ◽  
Slow Growing ◽  
Labium Majus

A 25 years old nulliparous regularly menstruating woman presented inShSMC Hospital with the complaints of swelling in the right side of vulva and Dysparunia for 4 months. The swelling was initially small and painless but later on it became painful. The swelling recurred after surgical treatment. Examination revealed a swelling in the right Labium majus which was about 4x3 cm, bulging into right side of vagina. It was diagnosed as a case of recurrent bartholin cyst but during surgical procedure it was apparent that the swelling was not bartholin cyst but some other fleshy structure. The removed mass was 7x4 cm. Histopathology revealed benign lesion containing hypocellular structure with large blood vessels and no malignancy. It was diagnosed as Aggressive angoimyxoma. Aggressive Angoimyxoma is a very rare mesenchymal tumor, uptil now only 200 case have been reported in the world. It is a slow growing benign tumor which is typically located in the pelvis and perineum. It often presents with asymptomatic perineal or vulval mass and may be confused with Bartholin’s cyst, lipoma or hernia. Local recurrence is upto 70%; metastasis is very rare. Treatment is surgical resection Histology reveals a mass of mixed mesenchymal origin with low mitotic activity.It is a hypocellular and highly vascular tumor with myxoid stroma.Bangladesh J Obstet Gynaecol, 2014; Vol. 29(1) : 46-48

scholarly journals A Case Report of Aggressive Angiomyxoma in Pregnancy: Do Hormones Play a Role?

2016 ◽  
Vol 2016 ◽  
pp. 1-4
Author(s):  
Theofano Orfanelli ◽  
Chi-Son Kim ◽  
Sally F. Vitez ◽  
James Van Gurp ◽  
Neeti Misra
Keyword(s):  
Case Report ◽  
Case Reports ◽  
Rare Condition ◽  
Final Diagnosis ◽  
Reproductive Age ◽  
Aggressive Angiomyxoma ◽  
The Right ◽  
Labium Majus ◽  
Growing Mass ◽  
In Pregnancy

Aggressive angiomyxoma is a rare, locally invasive tumor that generally affects the perineum and pelvis of reproductive age females. Aggressive angiomyxoma is often misdiagnosed, resulting in the delay of the treatment. Case reports show increased growth of the tumor during pregnancy, thus suggesting a hormonal dependency. We report this rare condition in a 29-year-old primigravid female with a growing mass on the right labium majus at 20 weeks’ gestation. The patient also developed a smaller mass on the left labium majus at 37 weeks’ gestation. The patient underwent a primary cesarean section with resection of the right labial mass, with a final diagnosis of aggressive angiomyxoma. The lesion on her left labium majus resolved spontaneously postpartum. This case report supports a hormonal involvement in this tumor.

scholarly journals Recurrent transperineal aggressive angiomyxoma: a case report

2021 ◽  
Author(s):  
Xiaoli Li ◽  
Chunxia Zhou ◽  
Jun Lin
Keyword(s):  
Rare Disease ◽  
Clinical Work ◽  
Large Mass ◽  
Aggressive Angiomyxoma ◽  
Mri Scan ◽  
Case Presentation ◽  
Vulvar Disease ◽  
Recurrent Case ◽  
The Right ◽  
Labium Majus

Abstract Background: aggressive angiomyxoma is a rare disease that may cause misdiagnosed in the clinical work and the characteristic of this disease is low potential malignancy. This case show a recurrent case of aggressive angiomyxoma 7 years after the surgery which was mistakenly diagnosed at that time.Case presentation: the patient presented a large mass in the right labium majus without any pain. This mass was recurrent 7 years after she received a surgery about the mass occurred at the same place which was diagnosed as vulvar angiomyofibroblastoma. She took the ultrasound scan and MRI scan and underwent the surgery again. This mass was excision completely. At this time, pathologist checked the HE stained slides and immunohistochemistry staining slides, then come the conclusion that this mass was aggressive angiomyxoma. We rechecked the pathological slides 7 tears ago and found out it was misdiagnosed at that time.Conclusions: Aggressive angiomyxoma is a rare tumor. This case presents a rare disease that may be misdiagnosed as other benign vulvar disease even after the surgery which get pathologic evidence. So we need to know more abou this disease.

scholarly journals Hydrocele of the Canal of Nuck with Endometriosis: Right-Side Dominance Confirmed by Literature Review and Statistical Analysis

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Shunsuke Nagase ◽  
Kanako Ogura ◽  
Karin Ashizawa ◽  
Asumi Sakaguchi ◽  
Ryo Wada ◽  
...  
Keyword(s):  
Cystic Mass ◽  
Serous Fluid ◽  
Case Presentation ◽  
Retrograde Menstruation ◽  
Canal Of Nuck ◽  
Magnetic Resonance Imaging Mri ◽  
The Right ◽  
Side Dominance ◽  
First Time ◽  
Labium Majus

Introduction. The canal of Nuck is an embryological remnant of the peritoneal pouch that extends into the labium majus of women. Hydrocele is the most common presentation, but only a small number of cases are reported in association with endometriosis. Case Presentation. The patient is a 45-year-old woman who presented with left inguinal mass with persistent pain. Computed tomography (CT) and magnetic resonance imaging (MRI) revealed a 30 mm cystic mass, and a hydrocele of the canal of Nuck (HCN) was suspected. The excised mass was a cyst containing yellow-tan serous fluid, and the cyst wall was lined by mesothelium. The morphology was consistent with conventional HCN. However, since several foci of endometrial-like epithelium and stroma were identified beneath the mesothelium, the mass was diagnosed with HCN with endometriosis (EM-HCN). Discussion. Right-side dominance of EM-HCN is suggested by several authors, but a thorough review has never been performed. For the first time, we reviewed the literature and statistically confirmed that EM-HCNs dominantly occur on the right side compared to those without endometriosis. We consider that this supports the theory that endometriosis derives from retrograde menstruation of endometrial tissue through fallopian tubes. When endometriosis is discovered in HCN, the clinician should be aware of the possibility of pelvic endometriosis.

scholarly journals Mammary gland in vulva (rare clinical case)

2012 ◽  
Vol 93 (5) ◽  
pp. 838-840
Author(s):  
L A Kozlov ◽  
V I Zhuravleva
Keyword(s):  
Mammary Gland ◽  
Breast Milk ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Histological Examination ◽  
Basal Cell ◽  
Clinical Case ◽  
The Right ◽  
Labium Majus

A rare clinical case of a patient with fibroadenoma of the vulva’s right labium majus with a typical hystological structure of mammary grand is described. The patient noticed a tumor of the right labium majus approximately 10 years before admission. After the childbirth while breastfeeding patient noticed a whitish discharge form the tumor which looked like breast milk. At the oncologic dispensary biopsy was performed after the tumor punction, atypical basal epithelium was found, and the basal cell carcinoma was suspected. Histological examination revealed fibroadenoma with a typical hystological structure of mammary grand.

Squamous cell carcinoma of the Bartholin Gland: A rare genital cancer managed at the JFK Liberian-Japanese Friendship Maternity Hospital Monrovia, Liberia

2021 ◽  
Vol 3 (2) ◽  
Author(s):  
Oghenefegor E. Olokor ◽  
Etedafe P. Gharoro ◽  
Ayyuba Rabiu ◽  
Ehigha Enabudoso ◽  
Daniel Kofa
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Fine Needle Biopsy ◽  
Maternity Hospital ◽  
Vaginal Wall ◽  
Invasive Squamous Cell Carcinoma ◽  
Gland Carcinoma ◽  
The Right ◽  
Labium Majus

Bartholin gland carcinoma is a rare tumor that constitutes 2-7% of all vulvar cancers. We presented a 40-years-old multipara who presented to the outpatient Gynecologic clinic of the JFK Maternity Hospital with a complaint of painful vulvar swelling of 3 years duration. The swelling began as a small lump on the left labium majus and grew overtime becoming increasingly painful, ulcerated with associated bleeding and malodorous discharge. Her last sexual activity was 2 years ago, of which she experienced dyspareunia but no post coital bleeding. Vulva examination revealed an ulcerated fungating lesion involving the left labium majus and minus, firm, tender, extending 2 cm into left vaginal wall and lower aspect of the right labium minus. The diagnosis of Bartholin gland carcinoma was made with Bartholin gland abscess and Vulvar cancer as differentials. Preoperative Fine Needle biopsy (FNA) showed acute on chronic inflammation of the Bartholin gland. A left hemivulvectomy was done and specimen was sent for histology, which revealed locally invasive squamous cell carcinoma of the Bartholin gland. Patient recovery was uneventful and she was discharged home 2 weeks post operatively on supplements and advised to follow up for chemotherapy.

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