Reflectance confocal microscopy: non-invasive distinction between actinic keratosis and squamous cell carcinoma

2014 ◽  
Vol 29 (7) ◽  
pp. 1302-1309 ◽  
Author(s):  
M. Peppelman ◽  
K.P. Nguyen ◽  
L. Hoogedoorn ◽  
P.E.J. van Erp ◽  
M.-J.P. Gerritsen
Keyword(s):  
Squamous Cell Carcinoma ◽  
Confocal Microscopy ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Actinic Keratosis ◽  
Reflectance Confocal Microscopy ◽  
Non Invasive

scholarly journals In Vivo Reflectance Confocal Microscopy-Diagnostic Criteria for Actinic Cheilitis and Squamous Cell Carcinoma of the Lip

2020 ◽  
Vol 9 (6) ◽  
pp. 1987
Author(s):  
Mihai Lupu ◽  
Ana Caruntu ◽  
Daniel Boda ◽  
Constantin Caruntu
Keyword(s):  
Squamous Cell Carcinoma ◽  
Confocal Microscopy ◽  
Blood Vessel ◽  
Cell Carcinoma ◽  
Diagnostic Criteria ◽  
Squamous Cell ◽  
Reflectance Confocal Microscopy ◽  
Target Cells ◽  
Actinic Cheilitis

Actinic cheilitis (AC) is one of the most frequent pathologies to affect the lips. Studies show that the most commonplace oral malignancy, squamous cell carcinoma (SCC), often emerges from AC lesions. Invasive diagnostic techniques performed on the lips carry a high risk of complications, but reflectance confocal microscopy (RCM), a non-invasive skin imaging technique, may change the current diagnostic pathway. This retrospective study was aimed at consolidating the RCM diagnostic criteria for AC and lip SCC. The study was conducted in two tertiary care centers in Bucharest, Romania. We included adults with histopathologically confirmed AC and SCC who also underwent RCM examination. Of the twelve lesions included in the study, four were AC and eight were SCC. An atypical honeycomb pattern and the presence of target cells in the epidermis were RCM features associated with AC. SCC was typified by the presence of complete disruption of the epidermal architecture and dermal inflammatory infiltrates. The mean blood vessel diameter in SCC was 18.55 µm larger than that in AC (p = 0.006) and there was no significant difference (p = 0.64) in blood vessel density, as measured by RCM, between SCC and AC. These data confirm that RCM can be useful for the in vivo distinction between AC and lip SCC.

Reflectance Confocal Microscopy Criteria of Pigmented Squamous Cell Carcinoma In Situ

2018 ◽  
Vol 40 (3) ◽  
pp. 173-179 ◽  
Author(s):  
Neda Shahriari ◽  
Jane M. Grant-Kels ◽  
Harold S. Rabinovitz ◽  
Margaret Oliviero ◽  
Alon Scope
Keyword(s):  
Squamous Cell Carcinoma ◽  
Confocal Microscopy ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Carcinoma In Situ ◽  
Reflectance Confocal Microscopy

scholarly journals Reflectance confocal microscopy of an inverted follicular keratosis mimicking a squamous cell carcinoma

2017 ◽  
Vol 7 (4) ◽  
pp. 39-42
Author(s):  
Sarah Hocker ◽  
Harold Rabinovitz ◽  
Margaret Oliviero ◽  
Jane Grant-Kels ◽  
Alon Scope
Keyword(s):  
Squamous Cell Carcinoma ◽  
Confocal Microscopy ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Reflectance Confocal Microscopy

Reflectance confocal microscopy (RCM)-based criteria for progression of lower-lip squamous cell carcinoma: A prospective study

Oral Oncology ◽  
2022 ◽  
Vol 125 ◽  
pp. 105674
Author(s):  
Paula Silva Ferreira ◽  
Lilian Rocha ◽  
Ana Patricia Carneiro Bezerra ◽  
Marcello Menta Simonsen Nico ◽  
Silvia Vanessa Lourenço
Keyword(s):  
Squamous Cell Carcinoma ◽  
Confocal Microscopy ◽  
Prospective Study ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Reflectance Confocal Microscopy ◽  
Lower Lip ◽  
A Prospective Study
Sign in / Sign up

Export Citation Format

Share Document