Alleviation of chronic venous leg ulcers with a hand-held dielectric barrier discharge plasma generator (PlasmaDerm® VU-2010): results of a monocentric, two-armed, open, prospective, randomized and controlled trial (NCT01415622)

2014 ◽  
Vol 29 (1) ◽  
pp. 148-155 ◽  
Author(s):  
F. Brehmer ◽  
H.A. Haenssle ◽  
G. Daeschlein ◽  
R. Ahmed ◽  
S. Pfeiffer ◽  
...  
Keyword(s):  
Dielectric Barrier Discharge ◽  
Discharge Plasma ◽  
Barrier Discharge ◽  
Controlled Trial ◽  
Plasma Generator ◽  
Leg Ulcers ◽  
Dielectric Barrier Discharge Plasma ◽  
Dielectric Barrier ◽  
Venous Leg Ulcers ◽  
Barrier Discharge Plasma

scholarly journals Fast and easy disinfection of coronavirus-contaminated face masks using ozone gas produced by a dielectric barrier discharge plasma generator

2020 ◽  
Author(s):  
Jinyeop Lee ◽  
Cheolwoo Bong ◽  
Pan K. Bae ◽  
Abdurhaman T. Abafogi ◽  
Seung H. Baek ◽  
...  
Keyword(s):  
Dielectric Barrier Discharge ◽  
Discharge Plasma ◽  
Barrier Discharge ◽  
Plasma Generator ◽  
Dielectric Barrier Discharge Plasma ◽  
Easy Method ◽  
Dielectric Barrier ◽  
Short Period ◽  
Barrier Discharge Plasma ◽  
Viral Envelopes

AbstractFace masks are one of the currently available options for preventing the transmission of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which has caused the 2019 pandemic. However, with the increasing demand for protection, face masks are becoming limited in stock, and the concerned individuals and healthcare workers from many countries are now facing the issue of the reuse of potentially contaminated masks. Although various technologies already exist for the sterilization of medical equipment, most of them are not applicable for eliminating virus from face masks. Thus, there is an urgent need to develop a fast and easy method of disinfecting contaminated face masks. In this study, using a human coronavirus (HCoV-229E) as a surrogate for SARS-CoV-2 contamination on face masks, we show that the virus loses its infectivity to a human cell line (MRC-5) when exposed for a short period of time (1 min) to ozone gas produced by a dielectric barrier discharge plasma generator. Scanning electron microscopy and particulate filtration efficiency (PFE) tests revealed that there was no structural or functional deterioration observed in the face masks even after they underwent excessive exposure to ozone (five 1-minute exposures). Interestingly, for face masks exposed to ozone gas for 5 min, the amplification of HCoV-229E RNA by reverse transcription polymerase chain reaction suggested a loss of infectivity under the effect of ozone, primarily owing to the damage caused to viral envelopes or envelope proteins. Ozone gas is a strong oxidizing agent with the ability to kill viruses on hard-to-reach surfaces, including the fabric structure of face masks. These results suggest that it may be possible to rapidly disinfect contaminated face masks using a plasma generator in a well-ventilated place.

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