Sentinel lymph node status is the strongest independent predictor for disease free and overall survival in patients with thick melanoma

2012 ◽  
Vol 27 (11) ◽  
pp. 1454-1456 ◽  
Author(s):  
T. Gambichler ◽  
L. Scholl
Keyword(s):  
Overall Survival ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Independent Predictor ◽  
Lymph Node Status ◽  
Node Status ◽  
Disease Free ◽  
Thick Melanoma ◽  
Sentinel Lymph Node Status

scholarly journals Excision margins and sentinel lymph node status as prognostic factors in thick melanoma of the head and neck: A retrospective analysis

Head & Neck ◽  
2016 ◽  
Vol 38 (9) ◽  
pp. 1373-1379 ◽  
Author(s):  
Olivia Ruskin ◽  
Alexandra Sanelli ◽  
Alan Herschtal ◽  
Angela Webb ◽  
Ben Dixon ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Head And Neck ◽  
Retrospective Analysis ◽  
Lymph Node Status ◽  
Node Status ◽  
Excision Margins ◽  
Thick Melanoma ◽  
Sentinel Lymph Node Status

scholarly journals Prognostic factors of primary cutaneus melanoma

2014 ◽  
Vol 67 (11-12) ◽  
pp. 392-398
Author(s):  
Lazo Noveski ◽  
Julija Zhivadinovik ◽  
Niki Matveeva
Keyword(s):  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Disease Free Survival ◽  
Lymph Node Status ◽  
Free Survival ◽  
Node Status ◽  
Melanoma Patients ◽  
Lymph Node Positive ◽  
Disease Free ◽  
Sentinel Lymph Node Status

Introduction. The purpose of this study was to identify tumor characteristics of primary malignant melanoma predictive of sentinel lymph node positive status, and then to determine whether sentinel lymph node status has an impact on recurrence and survival. Material and Methods. A total of 100 patients with primary malignant skin melanoma were analyzed. The prospective melanoma database identified patients with histologically confirmed cutaneus melanoma, clinically negative and clinically positive regional lymph nodes with no evidence of distant disease, who had undergone surgery between April 2001 and May 2012. Univariate and multivariate analyses were performed to assess factors that predict sentinel lymph node positive status, recurrence and survival. Results. We identified Breslow?s thickness and lymphocytic response as independent predictors of sentinel lymph node status in cutaneous melanoma patients. Sentinel lymph node status was a significant predictor of disease free survival. Conclusion. Despite the limitation, this study confirms Breslow?s thickness and tumor lymphocytic infiltration as two factors predictive of sentinel lymph node metastasis in cutaneous melanoma patients. We also found sentinel lymph node status to be the most significant independent predictor of disease free survival and identified sentinel lymph node status as an important variable to consider when estimating the risk of regional recurrence.

The Prognostic Significance of Sentinel Lymph Node Status for Patients with Thick Melanoma

2016 ◽  
Vol 23 (S5) ◽  
pp. 938-945 ◽  
Author(s):  
Danielle M. Bello ◽  
Gang Han ◽  
Laura Jackson ◽  
Kaleigh Bulloch ◽  
Stephan Ariyan ◽  
...  
Keyword(s):  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Prognostic Significance ◽  
Lymph Node Status ◽  
Node Status ◽  
Thick Melanoma ◽  
Sentinel Lymph Node Status

scholarly journals P234 The role of pre-operative CT staging in predicting the sentinel lymph node status

The Breast ◽  
2011 ◽  
Vol 20 ◽  
pp. S55
Author(s):  
S. Khawaja ◽  
A. Huws ◽  
R. Kannan ◽  
H. Sumrien ◽  
Y. Sharaiha ◽  
...  
Keyword(s):  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Lymph Node Status ◽  
Node Status ◽  
Sentinel Lymph Node Status

scholarly journals Regression and Sentinel Lymph Node Status in Melanoma Progression

2018 ◽  
Vol 24 ◽  
pp. 1359-1365 ◽  
Author(s):  
Alina Florentina Letca ◽  
Loredana Ungureanu ◽  
Simona Corina Şenilă ◽  
Lavinia Elena Grigore ◽  
Ştefan Pop ◽  
...  
Keyword(s):  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Lymph Node Status ◽  
Melanoma Progression ◽  
Node Status ◽  
Sentinel Lymph Node Status

scholarly journals Dermoscopic Features as Predictors of BRAF Mutational Status and Sentinel Lymph Node Positivity in Primary Cutaneous Melanoma

2021 ◽  
pp. e2021040
Author(s):  
Nika Filipović ◽  
Mirna Šitum ◽  
Marija Buljan
Keyword(s):  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Kinase Inhibitors ◽  
Lymph Node Status ◽  
Short Article ◽  
Primary Cutaneous Melanoma ◽  
Mutation Status ◽  
Node Status ◽  
Mutational Status ◽  
Sentinel Lymph Node Status

Dermoscopy is a diagnostic tool widely used in clinical practice for the detection of skin tumors, especially early stages of melanoma. Recent studies have shown that different dermoscopic features are associated with important prognostic parameters of melanoma, such as BRAF mutational status and sentinel lymph node status. More than half of all melanomas harbor a mutation in the BRAF oncogene. The current management of advanced-stage melanomas is greatly determined by the presence or absence of a mutation in this gene, as targeted therapy with BRAF kinase inhibitors is one of the first therapeutic choices for these patients. Sentinel lymph node status is one of the most significant predictors of a melanoma patient’s survival. Recent studies have shown that different dermoscopic patterns are also associated with sentinel lymph node status. This short article reviews studies that investigated correlations between dermoscopic features, BRAF mutation status and sentinel lymph node status.

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